Ndufs4 knockout mice with isolated complex I deficiency engage a futile adaptive brain response.

Autor: van de Wal MAE; Department of Pediatrics, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, the Netherlands; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen, the Netherlands., Doornbos C; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, the Netherlands., Bibbe JM; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, the Netherlands., Homberg JR; Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands., van Karnebeek C; Departments of Pediatrics and Human Genetics, Emma Center for Personalized Medicine, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, the Netherlands; United for Metabolic Diseases, the Netherlands., Huynen MA; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, the Netherlands., Keijer J; Human and Animal Physiology, Wageningen University, Wageningen, the Netherlands., van Schothorst EM; Human and Animal Physiology, Wageningen University, Wageningen, the Netherlands., 't Hoen PAC; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, the Netherlands., Janssen MCH; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands., Adjobo-Hermans MJW; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, the Netherlands., Wieckowski MR; Laboratory of Mitochondrial Biology and Metabolism, Nencki Institute of Experimental Biology, Warsaw, Poland., Koopman WJH; Department of Pediatrics, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, the Netherlands; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Human and Animal Physiology, Wageningen University, Wageningen, the Netherlands. Electronic address: Werner.Koopman@radboudumc.nl.

Publikováno v: Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2025 Jan 01; Vol. 1873 (1), pp. 141055. Date of Electronic Publication: 2024 Oct 11.

An online resource for GPCR structure determination and analysis.

Autor: Munk C; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. christian.munk@sund.ku.dk., Mutt E; Paul Scherrer Institute, Villigen, Switzerland., Isberg V; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Novozymes A/S, Copenhagen, Denmark., Nikolajsen LF; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Bibbe JM; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Flock T; Paul Scherrer Institute, Villigen, Switzerland., Hanson MA; GPCR Consortium, San Marcos, CA, USA., Stevens RC; Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA.; iHuman Institute, ShanghaiTech University, Shanghai, China., Deupi X; Paul Scherrer Institute, Villigen, Switzerland., Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. david.gloriam@sund.ku.dk.

Publikováno v: Nature methods [Nat Methods] 2019 Feb; Vol. 16 (2), pp. 151-162. Date of Electronic Publication: 2019 Jan 21.