Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.

Autor: Bachmann M; Department of Biology, University of Padova, Padova, Italy. magdalena.bachmann@unipd.it., Rossa A; Department of Chemical Sciences, University of Padova, Padova, Italy., Varanita T; Department of Biology, University of Padova, Padova, Italy., Fioretti B; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy., Biasutto L; CNR Institute of Neuroscience, Padova, Italy., Milenkovic S; CNR Institute of Materials, Cagliari, Italy., Checchetto V; Department of Biology, University of Padova, Padova, Italy., Peruzzo R; Department of Biology, University of Padova, Padova, Italy., Ahmad SA; Department of Surgery, University of Cincinnati, Cincinnati, USA., Patel SH; Department of Surgery, University of Cincinnati, Cincinnati, USA., Lukowski R; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany., Edwards MJ; Department of Surgery, University of Cincinnati, Cincinnati, USA., Ceccarelli M; CNR Institute of Materials, Cagliari, Italy.; Department of Physics, University of Cagliari, Monserrato, Italy., Gulbins E; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany., Zoratti M; CNR Institute of Neuroscience, Padova, Italy., Mattarei A; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. andrea.mattarei@unipd.it., Szabo I; Department of Biology, University of Padova, Padova, Italy. ildiko.szabo@unipd.it.

Publikováno v: Cell death & disease [Cell Death Dis] 2022 Dec 20; Vol. 13 (12), pp. 1055. Date of Electronic Publication: 2022 Dec 20.

DA7R: A 7-Letter Zip Code to Target PDAC.

Autor: Parrasia S; Department of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy., Rossa A; Department of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy., Roncaglia N; Department of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy.; CNR Institute of Biomolecular Chemistry, Padua Unit, Via F. Marzolo 1, 35131 Padova, Italy., Mattarei A; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131 Padova, Italy., Honisch C; CNR Institute of Biomolecular Chemistry, Padua Unit, Via F. Marzolo 1, 35131 Padova, Italy., Szabò I; Department of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy., Ruzza P; CNR Institute of Biomolecular Chemistry, Padua Unit, Via F. Marzolo 1, 35131 Padova, Italy., Biasutto L; CNR Neuroscience Institute, Padua Unit, Viale G. Colombo 3, 35131 Padova, Italy.

Publikováno v: Pharmaceutics [Pharmaceutics] 2023 May 16; Vol. 15 (5). Date of Electronic Publication: 2023 May 16.

Corrigendum to 'Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family' [Redox Biol. 37 (2020 Sep 6) 101705–101721](S2213231720309101)(10.1016/j.redox.2020.101705)

Autor: Peruzzo, R., Mattarei, A., Azzolini, M., Becker-Flegler, K. A., Romio, M., Rigoni, G., Carrer, A., Biasutto, L., Parrasia, S., Kadow, S., Manago, A., Urbani, A., Rossa, A., Semenzato, G., Soriano, M. E., Trentin, L., Ahmad, S., Edwards, M., Gulbins, E., Paradisi, C., Zoratti, M., Leanza, L., Szabo, I.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3657::7ba512c246d10bf29880e6b8a6a81e48
http://hdl.handle.net/11577/3439456

Peptides as Pharmacological Carriers to the Brain: Promises, Shortcomings and Challenges.

Autor: Parrasia S; Department of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy., Szabò I; Department of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy., Zoratti M; CNR Neuroscience Institute, Viale G. Colombo 3, 35131 Padova, Italy.; Department of Biomedical Sciences, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy., Biasutto L; CNR Neuroscience Institute, Viale G. Colombo 3, 35131 Padova, Italy.; Department of Biomedical Sciences, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2022 Nov 07; Vol. 19 (11), pp. 3700-3729. Date of Electronic Publication: 2022 Sep 29.

Corrigendum to "Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family" [Redox Biol. 37 (2020 Sep 6) 101705-101721].

Autor: Peruzzo R; Department of Biology, University of Padua, Italy., Mattarei A; Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Italy., Azzolini M; Department of Biomedical Sciences, University of Padua, Italy., Becker-Flegler KA; Department of Molecular Biology, University of Duisburg-Essen, Germany., Romio M; Department of Chemical Sciences, University of Padua, Italy., Rigoni G; Department of Biology, University of Padua, Italy., Carrer A; Department of Biology, University of Padua, Italy; Department of Biomedical Sciences, University of Padua, Italy., Biasutto L; Department of Biomedical Sciences, University of Padua, Italy; CNR Institute of Neuroscience, Padua, Italy., Parrasia S; Department of Biomedical Sciences, University of Padua, Italy., Kadow S; Department of Molecular Biology, University of Duisburg-Essen, Germany., Managò A; Department of Biology, University of Padua, Italy., Urbani A; Department of Biology, University of Padua, Italy; Department of Biomedical Sciences, University of Padua, Italy., Rossa A; Department of Chemical Sciences, University of Padua, Italy., Semenzato G; Department of Medicine, University of Padua, Italy., Soriano ME; Department of Biology, University of Padua, Italy., Trentin L; Department of Medicine, University of Padua, Italy., Ahmad S; Department of Surgery, Medical School, University of Cincinnati, USA., Edwards M; Department of Surgery, Medical School, University of Cincinnati, USA., Gulbins E; Department of Molecular Biology, University of Duisburg-Essen, Germany., Paradisi C; Department of Chemical Sciences, University of Padua, Italy., Zoratti M; Department of Biomedical Sciences, University of Padua, Italy; CNR Institute of Neuroscience, Padua, Italy., Leanza L; Department of Biology, University of Padua, Italy., Szabò I; Department of Biology, University of Padua, Italy; CNR Institute of Neuroscience, Padua, Italy. Electronic address: ildiko.szabo@unipd.it.

Publikováno v: Redox biology [Redox Biol] 2021 Sep; Vol. 45, pp. 102036. Date of Electronic Publication: 2021 Jun 29.