Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Biaoyang Lin"'
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5681-5695 (2021)
Abstract In patients with prostate cancer (PCa), there is a high rate of overdiagnosis and frequent overtreatment. Therefore, there is an urgent need for more accurate prediction of biochemical recurrence (BCR). DNA methylation regulation patterns pl
Externí odkaz:
https://doaj.org/article/de8c5cb662d24121b32e18def75855fa
Autor:
Waqas Azeem, Margrete Reime Hellem, Jan Roger Olsen, Yaping Hua, Kristo Marvyin, Yi Qu, Biaoyang Lin, Xisong Ke, Anne Margrete Øyan, Karl-Henning Kalland
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177861 (2017)
The androgen receptor (AR) transcription factor plays a key role in the development and progression of prostate cancer, as is evident from the efficacy of androgen-deprivation therapy, AR is also the most frequently mutated gene, in castration resist
Externí odkaz:
https://doaj.org/article/3a63f1dfd7674a55960d2cc38fba377f
Autor:
Jan Roger Olsen, Anne Margrete Oyan, Kari Rostad, Margrete R Hellem, Jie Liu, Lisha Li, David R Micklem, Hallvard Haugen, James B Lorens, Varda Rotter, Xi-Song Ke, Biaoyang Lin, Karl-Henning Kalland
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62547 (2013)
The transcription factor p63 is central for epithelial homeostasis and development. In our model of epithelial to mesenchymal transition (EMT) in human prostate cells, p63 was one of the most down-regulated transcription factors during EMT. We theref
Externí odkaz:
https://doaj.org/article/d7fd1bb4aff245c3a9fcd44b2011fe53
Autor:
Jiaofang Shao, Xiaoyan Lou, Jun Wang, Jing Zhang, Chen Chen, Dasong Hua, Fan Mo, Xu Han, Shu Zheng, Biaoyang Lin
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70307 (2013)
Recent studies have demonstrated the power of deep re-sequencing of the whole genome or exome in understanding cancer genomes. However, targeted capture of selected genomic whole gene-body regions, rather than the whole exome, have several advantages
Externí odkaz:
https://doaj.org/article/4476115592de4002ac362ee49be3970d
Autor:
Dong Ding, Xiaoyan Lou, Dasong Hua, Wei Yu, Lisha Li, Jun Wang, Feng Gao, Na Zhao, Guoping Ren, Lanjuan Li, Biaoyang Lin
Publikováno v:
PLoS Genetics, Vol 8, Iss 12, p e1003065 (2012)
Integration of the viral DNA into host chromosomes was found in most of the hepatitis B virus (HBV)-related hepatocellular carcinomas (HCCs). Here we devised a massive anchored parallel sequencing (MAPS) method using next-generation sequencing to iso
Externí odkaz:
https://doaj.org/article/1222e2cb822e42cb8a1ba9d3cb4b2558
Autor:
Xu Han, Xuefeng Fang, Xiaoyan Lou, Dasong Hua, Wenchao Ding, Gregory Foltz, Leroy Hood, Ying Yuan, Biaoyang Lin
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41335 (2012)
SOX2 is an important stem cell marker and plays important roles in development and carcinogenesis. However, the role of SOX2 in Epithelial-Mesenchymal Transition has not been investigated. We demonstrated, for the first time, that SOX2 is involved in
Externí odkaz:
https://doaj.org/article/903577549fe54d6e8fc464de68b776ed
Autor:
Wei Yu, Chengmeng Jin, Xiaoyan Lou, Xu Han, Lisha Li, Yinghua He, Hongyu Zhang, Kelong Ma, Jingde Zhu, Lihua Cheng, Biaoyang Lin
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29450 (2011)
Cisplatin resistance is one of the major reasons leading to the high death rate of ovarian cancer. Methyl-Capture sequencing (MethylCap-seq), which combines precipitation of methylated DNA by recombinant methyl-CpG binding domain of MBD2 protein with
Externí odkaz:
https://doaj.org/article/db164ad08b184f3dbdc0e53b0a7064b6
Autor:
Qichao Huang, Biaoyang Lin, Hanqiang Liu, Xi Ma, Fan Mo, Wei Yu, Lisha Li, Hongwei Li, Tian Tian, Dong Wu, Feng Shen, Jinliang Xing, Zhi-Nan Chen
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26168 (2011)
RNA-seq is a powerful tool for comprehensive characterization of whole transcriptome at both gene and exon levels and with a unique ability of identifying novel splicing variants. To date, RNA-seq analysis of HBV-related hepatocellular carcinoma (HCC
Externí odkaz:
https://doaj.org/article/c746533e235f4c27b518af4bb3ccdf43
Autor:
Nameeta Shah, Biaoyang Lin, Zita Sibenaller, Timothy Ryken, Hwahyung Lee, Jae-Geun Yoon, Steven Rostad, Greg Foltz
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16146 (2011)
O⁶-methylguanine DNA-methyltransferase (MGMT) promoter methylation has been identified as a potential prognostic marker for glioblastoma patients. The relationship between the exact site of promoter methylation and its effect on gene silencing, and
Externí odkaz:
https://doaj.org/article/489dd831b59b41de84b3b108795264e2
Autor:
Gregory J Hather, Winston Haynes, Roger Higdon, Natali Kolker, Elizabeth A Stewart, Peter Arzberger, Patrick Chain, Dawn Field, B Robert Franza, Biaoyang Lin, Folker Meyer, Vural Ozdemir, Charles V Smith, Gerald van Belle, John Wooley, Eugene Kolker
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12203 (2010)
To gauge the current commitment to scientific research in the United States of America (US), we compared federal research funding (FRF) with the US gross domestic product (GDP) and industry research spending during the past six decades. In order to a
Externí odkaz:
https://doaj.org/article/21f5d9b57168445ebaa60c1ea1f9edd0