Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Biaoyan Du"'
Autor:
Jiawei Chen, Shan Hu, Huiqi Wang, Tingxiu Zhao, Yue Song, Xueying Zhong, Qingling Luo, Mansi Xu, Lina He, Qiugu Chen, Biaoyan Du, Jianyong Xiao, Kun Wang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Melanoma is the most lethal type of skin cancer. Despite the breakthroughs in the clinical treatment of melanoma using tumor immunotherapy, many patients do not benefit from these immunotherapies because of multiple immunosuppressive mechani
Externí odkaz:
https://doaj.org/article/3da8feea66864383a3e74f4c5c8c1023
Autor:
Wenbo Zhang, Lingyun Lin, Yujian Zhang, Tingxiu Zhao, Yujuan Zhan, Huiqi Wang, Junfeng Fang, Biaoyan Du
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 150, Iss , Pp 112973- (2022)
Dioscin (Dio), steroid saponin, exists in several medicinal herbs with potent anticancer efficacy. This study aimed to explore the effect of Dio on the immune-related modulation and synergistic therapeutic effects of the herpes simplex virus thymidin
Externí odkaz:
https://doaj.org/article/c2da2a364eb646cb8429741a23773dd1
Autor:
Zhiying Huang, Shu Gan, Xuerong Zhuang, Yao Chen, Linlin Lu, Ying Wang, Xiaoxiao Qi, Qian Feng, Qiuju Huang, Biaoyan Du, Rong Zhang, Zhongqiu Liu
Publikováno v:
Cells, Vol 11, Iss 16, p 2472 (2022)
Although artesunate has been reported to be a promising candidate for colorectal cancer (CRC) treatment, the underlying mechanisms and molecular targets of artesunate are yet to be explored. Here, we report that artesunate acts as a senescence and au
Externí odkaz:
https://doaj.org/article/9ee91bbe8b9f4cdca49494c4991ee51a
Autor:
Kun Wang, Qing Gong, Yujuan Zhan, Bonan Chen, Ting Yin, Yuhua Lu, Yilin Zhang, Huiqi Wang, Junzi Ke, Biaoyan Du, Xiaodong Liu, Jianyong Xiao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
Cancer cells are characterized by malignant proliferation and aberrant metabolism and are thereby liable to the depletion of nutrients and accumulation of metabolic waste. To maintain cellular homeostasis, cancer cells are prone to upregulating the c
Externí odkaz:
https://doaj.org/article/a5618f34f1954baaa21ad540f065c6ea
Autor:
Hong Li, Haiyan Du, Guangxian Zhang, Yingya Wu, Pengxiang Qiu, Jingjing Liu, Jing Guo, Xijuan Liu, Lingling Sun, Biaoyan Du, Yuhui Tan
Publikováno v:
PeerJ, Vol 7, p e7760 (2019)
Melanoma is a global concern and accounts for the major mortality of skin cancers. Herpes simplex virus thymidine kinase gene with ganciclovir (HSV-TK/GCV) is a promising gene therapy for melanoma. Despite its low efficiency, it is well known for its
Externí odkaz:
https://doaj.org/article/680e701854334a31b06f22e418fc44ab
Autor:
Kun Wang, Bonan Chen, Ting Yin, Yujuan Zhan, Yuhua Lu, Yilin Zhang, Jiawei Chen, Weijie Wu, Shikun Zhou, Wenli Mao, Yuhui Tan, Biaoyan Du, Xiaodong Liu, Hiuting Idy HO, Jianyong Xiao
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3415 (2019)
The main mechanistic function of most chemotherapeutic drugs is mediated by inducing mitochondria-dependent apoptosis. Tumor cells usually respond to upregulate autophagy to eliminate impaired mitochondria for survival. Hypothetically, inhibiting aut
Externí odkaz:
https://doaj.org/article/e40d1ae0640e4f148bdc55d6e8a6b7ff
Autor:
Yingyi Luo, Zhiyao Ren, Biaoyan Du, Shangping Xing, Shaowei Huang, Yunrong Li, Zhouxi Lei, Dan Li, Huanhuan Chen, Yuechun Huang, Gang Wei
Publikováno v:
Molecules, Vol 24, Iss 1, p 144 (2019)
ViceninII is a naturally flavonoid glycoside extracted from Dendrobium officinale, a precious Chinese traditional herb, has been proven to be valuable for cancer treatment. Transforming growth factor-β1 (TGF-β1), promotes the induction of epithelia
Externí odkaz:
https://doaj.org/article/6c1071708e8d4428afb1eca57e299989
Autor:
Yujuan Zhan, Kun Wang, Qiao Li, Yidan Zou, Bonan Chen, Qing Gong, Hiuting Idy HO, Ting Yin, Fangyuan Zhang, Yuhua Lu, Weijie Wu, Yilin Zhang, Yuhui Tan, Biaoyan Du, Xiaodong Liu, Jianyong Xiao
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3221 (2018)
Chemoresistance is a major limiting factor that impairs the outcome of non-small cell lung cancer (NSCLC) chemotherapy. Paclitaxel (Tax) induces protective autophagy in NSCLC cells, leading to the development of drug resistance. We recently identifie
Externí odkaz:
https://doaj.org/article/5922fb3832ec4e3dad6d8d676582d27d
Autor:
Hua Yi, Kun Wang, Biaoyan Du, Lina He, Hiuting HO, Maosong Qiu, Yidan Zou, Qiao Li, Junfeng Jin, Yujuan Zhan, Zhongxiang Zhao, Xiaodong Liu
Publikováno v:
Molecules, Vol 23, Iss 6, p 1338 (2018)
Aleuritolic acid (AA) is a triterpene that is isolated from the root of Croton crassifolius Geisel. In the present study, the cytotoxic effects of AA on hepatocellular carcinoma cells were evaluated. AA exerted dose- and time-dependent cytotoxicity b
Externí odkaz:
https://doaj.org/article/c780717e299a4674ad851cd82fd4ce2a
Autor:
Jianyong Xiao, Guangxian Zhang, Pengxiang Qiu, Xijuan Liu, Yingya Wu, Biaoyan Du, Jiefen Li, Jing Zhou, Jingjing Li, Yuhui Tan
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67662 (2013)
The bystander effect is an intriguing phenomenon by which adjacent cells become sensitized to drug treatment during gene therapy with herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV). This effect is reported to be mediated by gap juncti
Externí odkaz:
https://doaj.org/article/6cda1c4bc87b4b6b8677e9d068a13d0b