Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Biao-Xin Chai"'
Autor:
Jarl E. S. Wikberg, Jeffrey B. Tatro, Helgi Schiöth, Colin Pouton, Kathleen G. Mountjoy, Victor J. Hruby, Carrie Haskell-Luevano, Ira Gantz, Tung M. Fong, Sadaf Farooqi, Alex N. Eberle, Roger D. Cone, Adrian J. L. Clark, Biao-Xin Chai, Vanni Caruso
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Melanocortin receptors (provisional nomenclature as recommended by NC-IUPHAR [41]) are activated by members of the melanocortin family (α-MSH, β-MSH and γ-MSH forms; δ form is not found in mammals) and adrenocorticotrophin (ACTH). Endogenous anta
Publikováno v:
Endocrinology. 151:134-142
Ankyrin repeat and suppressor of cytokine signaling box-containing protein 4 (Asb-4) is specifically expressed in the energy homeostasis-related brain areas and colocalizes with proopiomelanocortin (POMC) neurons of the arcuate nucleus (ARC). Injecti
Publikováno v:
Cellular Signalling. 19:1185-1192
Asb-4 is a gene that is specifically expressed in the hypothalamic energy homeostasis-associated areas and is down-regulated in the arcuate nucleus of fasted Sprague Dawley and obese Zucker rats. It has two functional domains, the ankyrin repeat and
Autor:
Biao Xin Chai, Yu Mei Lai, Darren A. Thompson, Gregory S. Barsh, Ira Gantz, Glenn L. Millhauser, Richard R. Neubig, Chris J. Dickinson, Ji Yao Li, Pilgrim J. Jackson
Publikováno v:
Peptides. 24:603-609
Agouti and agouti-related protein (AgRP) are endogenous antagonists of the melanocortin receptors (MCxR). Previous data showed that recombinant full-length agouti and a synthetic fragment of AgRP, AgRP (83-132), are inverse agonists at the MC1R and M
Background The effects of intestinal inflammation on the central neurons projecting to the enteric nervous system are unknown. The dorsal motor nucleus of the vagus signals to the gastrointestinal system. Ghrelin is elevated in patients with inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab42e38949031b0a1b5e4852e152389
https://europepmc.org/articles/PMC2547415/
https://europepmc.org/articles/PMC2547415/
Publikováno v:
Surgery. 144(2)
Background The effects of intestinal inflammation on the central nervous system are unknown. The dorsal motor nucleus of the vagus (DMNV) integrates peripheral and central signals and sends efferent signals to the gastrointestinal system. The purpose
Autor:
Ravi P. Nargund, Ira Gantz, Michael W. Mulholland, Irina D. Pogozheva, Andrei L. Lomize, Biao Xin Chai, Henry I. Mosberg, Tung M. Fong, David H. Weinberg
Publikováno v:
Biochemistry. 44(34)
Specific interactions of human melanocortin-4 receptor (hMC4R) with its nonpeptide and peptide agonists were studied using alanine-scanning mutagenesis. The binding affinities and potencies of two synthetic, small-molecule agonists (THIQ, MB243) were
Autor:
Biao Xin Chai, Richard R. Neubig, Yu Mei Lai, Ira Gantz, Irina D. Pogozheva, Ji Yao Li, Henry I. Mosberg
Publikováno v:
Biochemistry. 44(9)
The molecular interactions between human melanocortin receptor-1 and -4 (hMC1R and hMC4R) and their endogenous antagonists, agouti signaling protein (ASIP) and agouti-related protein (AGRP), were assessed by studying the effects of site-directed muta
Autor:
Yu-guang, Wang, Yue, Gao, Biao-xin, Chai, Peng, Chen, Hong-ling, Tan, Yong-hong, Zhao, Cheng-rong, Xiao, Yuan-yuan, Sun, Li-jun, Zhu
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 29(4)
To study the modulatory effect of Panax gingseng and coadministration with Veratrum nigrum on the activity and mRNA expression of cytochrome P450 isoenzymes in rat liver.Rat liver microsomal cytochrome P450, b5, aminopyrine N-demethylase(APND), p-nit
Autor:
Biao Xin Chai, Pascal A. Lescure, Rork Kuick, David M. Kurnit, Ji Yao Li, Robert C. Thompson, Ira Gantz, George Michailidis, Samir M. Hanash, Rebecca M. Demo, Yu Mei Lai, David E. Misek
Publikováno v:
The Journal of biological chemistry. 277(11)
We used oligonucleotide microarrays to analyze comprehensively hypothalamic gene expression changes that correlate with energy homeostasis. We compared the hypothalamic gene expression profiles of freely fed and 48-h fasted rats using 26,379 oligonuc