Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Biao Cai"'
Publikováno v:
NeuroImage, Vol 297, Iss , Pp 120739- (2024)
Heritability and genetic covariance/correlation quantify the marginal and shared genetic effects across traits. They offer insights on the genetic architecture of complex traits and diseases. To explore how genetic variations contribute to brain func
Externí odkaz:
https://doaj.org/article/a3b746206ce34c39ac160256dfbfb55f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In this era of information explosion, recommendation systems play a key role in helping users to uncover content of interest among massive amounts of information. Pursuing a breadth of recall while maintaining accuracy is a core challenge fo
Externí odkaz:
https://doaj.org/article/6abb7fe982264ffda742117db78d8b3a
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 9, Pp 15999-16014 (2023)
The spine is one of the most important structures in the human body, serving to support the body, organs, protect nerves, etc. Medical image segmentation for the spine can help doctors in their clinical practice for rapid decision making, surgery pla
Externí odkaz:
https://doaj.org/article/8cbd99c951f341e885fa7bf3afc26ad0
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The advancement of single cell RNA-sequencing (scRNA-seq) technology has enabled the direct inference of co-expressions in specific cell types, facilitating our understanding of cell-type-specific biological functions. For this task, the hig
Externí odkaz:
https://doaj.org/article/3af3595e59a34cce8e7d77eb18523ec0
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Wilson's disease (WD) is an autosomal recessive disorder with a genetic basis. The predominant non-motor symptom of WD is cognitive dysfunction, although the specific genetic regulatory mechanism remains unclear. Tx-J mice, with an 82% seque
Externí odkaz:
https://doaj.org/article/2faa9e7082a947f79b559fc1a3e88824
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 4, Pp 6174-6190 (2023)
With the development of next-generation protein sequencing technologies, sequence assembly algorithm has become a key technology for de novo sequencing process. At present, the existing methods can address the assembly of an unknown single protein ch
Externí odkaz:
https://doaj.org/article/95ca97d5bc2349a0a11c6e1bcef22222
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 11, Pp 1561-1571 (2022)
Objectives: Huangpu Tongqiao Capsule (HPTQC) is a traditional Chinese medicine (TCM) that has been used to treat Alzheimer's disease (AD). This study was to explore the pharmacological action and molecular mechanism of HPTQC in the treatment of AD. M
Externí odkaz:
https://doaj.org/article/abccf9c442724e76be24aba2d115aa81
Autor:
Dennis May, Sangwon Yun, David G Gonzalez, Sangbum Park, Yanbo Chen, Elizabeth Lathrop, Biao Cai, Tianchi Xin, Hongyu Zhao, Siyuan Wang, Lauren E Gonzalez, Katie Cockburn, Valentina Greco
Publikováno v:
eLife, Vol 12 (2023)
Stem cell differentiation requires dramatic changes in gene expression and global remodeling of chromatin architecture. How and when chromatin remodels relative to the transcriptional, behavioral, and morphological changes during differentiation rema
Externí odkaz:
https://doaj.org/article/bad69eed39af49f392b7df15574378b3
Autor:
Hang Song, Jianye Zhang, Bin Liu, Jing Xu, Biao Cai, Hai Yang, Julia Straube, Xiyong Yu, Teng Ma
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Epigenetics including DNA and RNA modifications have always been the hotspot field of life sciences in the post-genome era. Since the first mapping of N6-methyladenosine (m6A) and the discovery of its widespread presence in mRNA, there are a
Externí odkaz:
https://doaj.org/article/2abf04dc27024f74a6701cb11119213f
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background The ratio of fPSA/tPSA in the "grey zone" of tPSA with the concentration range between 4 ng/ml and 10 ng/ml is significant for diagnosis of prostate cancer, and highly efficiency quantification of the ratio of fPSA/tPSA remain elu
Externí odkaz:
https://doaj.org/article/7476cc5d24ee4f6cadcc24e77c955b19