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pro vyhledávání: '"Bianka Haro"'
Autor:
Jasleen K. Sodhi, Bianka Haro, Khadjia A Lobo, Amit Kapadia, Mary A. Schleiff, Bernice Matusow, Christina Tantoy, Nikhilesh V Dhuria
Publikováno v:
Drug metabolism reviews. 53(2)
As lead optimization efforts have successfully reduced metabolic liabilities due to cytochrome P450 (CYP)-mediated metabolism, there has been an increase in the frequency of involvement of non-CYP enzymes in the metabolism of investigational compound