Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bianca Yaghoobi"'
Autor:
Bianca Yaghoobi, Galen W. Miller, Erika B. Holland, Xueshu Li, Danielle Harvey, Shuyang Li, Hans-Joachim Lehmler, Isaac N. Pessah, Pamela J. Lein
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Although their production was banned in the United States in 1977, polychlorinated biphenyls (PCBs) continue to pose significant risks to the developing nervous system. Perinatal exposure to PCBs is associated with increased risk of neuropsychiatric
Externí odkaz:
https://doaj.org/article/e52f53cbe31a4059bdf797f0a82eda23
Autor:
Anne E. Thessen, Skylar Marvel, J. C. Achenbach, Stephan Fischer, Melissa A. Haendel, Kimberly Hayward, Nils Klüver, Sarah Könemann, Jessica Legradi, Pamela Lein, Connor Leong, J. Erik Mylroie, Stephanie Padilla, Dante Perone, Antonio Planchart, Rafael Miñana Prieto, Arantza Muriana, Celia Quevedo, David Reif, Kristen Ryan, Evelyn Stinckens, Lisa Truong, Lucia Vergauwen, Colette Vom Berg, Mitch Wilbanks, Bianca Yaghoobi, Jon Hamm
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Toxicological evaluation of chemicals using early-life stage zebrafish (Danio rerio) involves the observation and recording of altered phenotypes. Substantial variability has been observed among researchers in phenotypes reported from similar studies
Externí odkaz:
https://doaj.org/article/aa31689544a84557af841ca42ae42ad4
Autor:
Bianca, Yaghoobi, Galen W, Miller, Erika B, Holland, Xueshu, Li, Danielle, Harvey, Shuyang, Li, Hans-Joachim, Lehmler, Isaac N, Pessah, Pamela J, Lein
Although their production was banned in the United States in 1977, polychlorinated biphenyls (PCBs) continue to pose significant risks to the developing nervous system. Perinatal exposure to PCBs is associated with increased risk of neuropsychiatric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5bf59800aa2ffad5bf5e6bb937cf61
https://escholarship.org/uc/item/8rn9x6zp
https://escholarship.org/uc/item/8rn9x6zp
Autor:
Paige C, Mundy, Brandon, Pressly, Dennis R, Carty, Bianca, Yaghoobi, Heike, Wulff, Pamela J, Lein
Publikováno v:
Toxicology and applied pharmacology
The chemical threat agent tetramethylenedisulfotetramine (TETS) is a γ-aminobutyric acid type A receptor (GABA AR) antagonist that causes life threatening seizures. Currently, there is no specific antidote for TETS intoxication. TETS-induced seizure
Autor:
Lindsay P. Cameron, Douglas Myers-Turnbull, Jayashri Viswanathan, Oliver Fiehn, Zachary Rabow, Guoliang Zhang, David E. Olson, Bianca Yaghoobi, Zefan Q. Hurley, Brandon M. Brown, Jamie Peters, David Kokel, Maxemiliano V. Vargas, Robert J. Tombari, Lauren J. Laskowski, Matthew N. McCarroll, John D. McCorvy, Alexander J. Pell, Taohui Liu, Pamela J. Lein, Jack C. Taylor, Yi Zuo, Ju Lu, Yann Ehinger, Michelle Tjia, Heike Wulff, Emilie I. Anderson, Lee E. Dunlap, Dorit Ron
Publikováno v:
Nature, vol 589, iss 7842
Nature
Nature
The psychedelic alkaloid ibogaine has anti-addictive properties in both humans and animals1. Unlike most medications for the treatment of substance use disorders, anecdotal reports suggest that ibogaine has the potential to treat addiction to various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac37c443462daef2d948da379f29fb96
https://escholarship.org/uc/item/5pp1d1vm
https://escholarship.org/uc/item/5pp1d1vm
Publikováno v:
Curr Opin Toxicol
A major goal of translational toxicology is to identify adverse chemical effects and determine whether they are conserved or divergent across experimental systems. Translational toxicology encompasses assessment of chemical toxicity across multiple l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d56643d819613be49a3cdf25e448102
https://escholarship.org/uc/item/1vh3q9qc
https://escholarship.org/uc/item/1vh3q9qc
Autor:
Kelly M Morales, Dennis R. Carty, Katharina Dach, Bianca Yaghoobi, Pamela J. Lein, Martin Schmuck
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology, vol 167, iss 1
To screen the tens of thousands of chemicals for which no toxicity data currently exists, it is necessary to move from in vivo rodent models to alternative models, such as zebrafish. Here, we used dechorionated Tropical 5D wild-type zebrafish embryos
Autor:
Xiaopeng Chen, Birgit Puschner, Galen W. Miller, Kyla M. Walter, Pamela J. Lein, Bianca Yaghoobi
Thyroid hormones (THs) regulate neurodevelopment, thus TH disruption is widely posited as a mechanism of developmental neurotoxicity for diverse environmental chemicals. Zebrafish have been proposed as an alternative model for studying the role of TH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c833d0372d4b8bac746bbe72eb9b16
https://escholarship.org/uc/item/23r0s95v
https://escholarship.org/uc/item/23r0s95v
Publikováno v:
Miller, Galen W; Chandrasekaran, Vidya; Yaghoobi, Bianca; & Lein, Pamela J. (2018). Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity.. Neurotoxicology, 67, 102-111. doi: 10.1016/j.neuro.2018.04.016. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/05b707r0
Chemical exposures have been implicated as environmental risk factors that interact with genetic susceptibilities to influence individual risk for complex neurodevelopmental disorders, including autism spectrum disorder, schizophrenia, attention defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb7ad52ac7f5d3e022704a46b0bc645
https://escholarship.org/uc/item/05b707r0
https://escholarship.org/uc/item/05b707r0