Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bianca Schrul"'
Autor:
Ravi Dhiman, Rehani S. Perera, Chetan S. Poojari, Haakon T. A. Wiedemann, Reinhard Kappl, Christopher W. M. Kay, Jochen S. Hub, Bianca Schrul
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Lipid droplet (LD) function relies on proteins partitioning between the endoplasmic reticulum (ER) phospholipid bilayer and the LD monolayer membrane to control cellular adaptation to metabolic changes. It has been proposed that these hairpi
Externí odkaz:
https://doaj.org/article/7f10e2741b6a4d20b44a744b27205537
Autor:
Anna A. Lauer, Daniel Janitschke, Malena dos Santos Guilherme, Vu Thu Thuy Nguyen, Cornel M. Bachmann, Sen Qiao, Bianca Schrul, Ulrich Boehm, Heike S. Grimm, Tobias Hartmann, Kristina Endres, Marcus O. W. Grimm
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Alzheimer’s disease (AD) is a very frequent neurodegenerative disorder characterized by an accumulation of amyloid-β (Aβ). Acitretin, a retinoid-derivative and approved treatment for Psoriasis vulgaris, increases non-amyloidogenic Amyloi
Externí odkaz:
https://doaj.org/article/5639c0b6d26b424195703800c12d0d3c
Autor:
Sven Lyschik, Anna A. Lauer, Tanja Roth, Daniel Janitschke, Markus Hollander, Thorsten Will, Tobias Hartmann, Ron R. Kopito, Volkhard Helms, Marcus O. W. Grimm, Bianca Schrul
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cellular lipid metabolism is tightly regulated and requires a sophisticated interplay of multiple subcellular organelles to adapt to changing nutrient supply. PEX19 was originally described as an essential peroxisome biogenesis factor that selectivel
Externí odkaz:
https://doaj.org/article/973e0dd8de814098ba1e3f71dcb7244d
Autor:
Richard Zimmermann, Sven Lang, Monika Lerner, Friedrich Förster, Duy Nguyen, Volkhard Helms, Bianca Schrul
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13028 (2021)
Protein import into the endoplasmic reticulum (ER) is the first step in the biogenesis of around 10,000 different soluble and membrane proteins in humans. It involves the co- or post-translational targeting of precursor polypeptides to the ER, and th
Externí odkaz:
https://doaj.org/article/9b1f93f5a7de44f5b3d167e6572976a4
Autor:
Wendelin Wolf, Annett Kilic, Bianca Schrul, Holger Lorenz, Blanche Schwappach, Matthias Seedorf
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39703 (2012)
The endoplasmic reticulum (ER) forms contacts with the plasma membrane. These contacts are known to function in non-vesicular lipid transport and signaling. Ist2 resides in specific domains of the ER in Saccharomyces cerevisiae where it binds phospho
Externí odkaz:
https://doaj.org/article/cc7200945eac4e79b79e27fa36b00035
Autor:
Sevde Puza, Stefanie Caesar, Chetan Poojari, Michael Jung, Ralf Seemann, Jochen S. Hub, Bianca Schrul, Jean‐Baptiste Fleury
Lipid droplets (LDs) are ubiquitous, cytoplasmic fat storage organelles that originate from the endoplasmic reticulum (ER) membrane. They are composed of a core of neutral lipids surrounded by a phospholipid monolayer. Proteins embedded into this mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8e1e4ce024da618270b384a3b6508b
Autor:
Sven A. Lang, Volkard Helms, Friedrich Förster, Richard Zimmermann, Monika Lerner, Duy Chinh Nguyen, Bianca Schrul
Protein import into the endoplasmic reticulum (ER) is the first step in the biogenesis of about 10,000 different soluble and membrane proteins in humans. It involves co- or post-translational targeting of precursor polypeptides to the ER and their su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f6cae2b38d458bde42c33ae0075200
Autor:
Janine Mett, Marcus O. W. Grimm, Anna A. Lauer, Matthias Riemenschneider, Heike S. Grimm, Ulrike Müller, Bianca Schrul, Christoph P Stahlmann, Tobias Hartmann, Cornel M Bachmann, Daniel Janitschke, Andrea Thiel, Felix Ritzmann, Reuven Stein
Publikováno v:
Aging Cell
One of the major pathological hallmarks of Alzheimer´s disease (AD) is an accumulation of amyloid‐β (Aβ) in brain tissue leading to formation of toxic oligomers and senile plaques. Under physiological conditions, a tightly balanced equilibrium b
Autor:
Wolfgang Schliebs, Bianca Schrul
Publikováno v:
Biological Chemistry. 399:741-749
In order to adapt to environmental changes, such as nutrient availability, cells have to orchestrate multiple metabolic pathways, which are catalyzed in distinct specialized organelles. Lipid droplets (LDs) and peroxisomes are both endoplasmic reticu
Autor:
Bianca Schrul, Ron R. Kopito
Publikováno v:
Nature cell biology
SUMMARY Lipid droplets (LDs) are endoplasmic reticulum (ER)-derived lipid storage organelles uniquely encapsulated by phospholipid monolayers. LD membrane proteins are embedded into the monolayer in a monotopic hairpin-topology and therefore likely h