Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Bianca N Islam"'
Autor:
Huabin Zhu, Henrique Lemos, Brinda Bhatt, Bianca N Islam, Abhijit Singh, Ashish Gurav, Lei Huang, Darren D Browning, Andrew Mellor, Sadanand Fulzele, Nagendra Singh
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183484 (2017)
Carbidopa is a drug that blocks conversion of levodopa to dopamine outside of central nervous system (CNS) and thus inhibits unwanted side effects of levodopa on organs located outside of CNS during management of Parkinson's Disease (PD). PD is assoc
Externí odkaz:
https://doaj.org/article/d0b131e0a8a048bdbe4051bc3e813bf3
Autor:
Sarah K Sharman, Bianca N Islam, Yali Hou, Margaux Usry, Allison Bridges, Nagendra Singh, Subbaramiah Sridhar, Satish Rao, Darren D Browning
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176673 (2017)
Guanylyl cyclase-C (GC-C) agonists increase cGMP levels in the intestinal epithelium to promote secretion. This process underlies the utility of exogenous GC-C agonists such as linaclotide for the treatment of chronic idiopathic constipation (CIC) an
Externí odkaz:
https://doaj.org/article/a56200b61a654704ae158505d1d4c3c7
Autor:
Darren D. Browning, Wonsuk Yoo, Subbaramiah Sridhar, Franklin G. Berger, Nagendra Singh, Yali Hou, Bianca N. Islam, Sarah K. Sharman
S1. Non-polyp tissues from Apc Min/+ mice have increased levels of proliferation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c870d147901707a2a2be4b7eec86092
https://doi.org/10.1158/1940-6207.22533401.v1
https://doi.org/10.1158/1940-6207.22533401.v1
Autor:
Darren D. Browning, Wonsuk Yoo, Subbaramiah Sridhar, Franklin G. Berger, Nagendra Singh, Yali Hou, Bianca N. Islam, Sarah K. Sharman
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7f176c52c03511adafef44008a349d
https://doi.org/10.1158/1940-6207.22533395.v1
https://doi.org/10.1158/1940-6207.22533395.v1
Autor:
Darren D. Browning, Subbaramiah Sridhar, Franklin G. Berger, Paulo C. Rodriguez, Jimena Trillo-Tinoco, Ravindra Kolhe, Sangmi Kim, Nagendra Singh, Allison E. Bridges, Yali Hou, Sarah K. Sharman, Bianca N. Islam
There are two supplementary figures. Figure S1 shows Western blot analysis of polyps from control and sildenafil treated mice, for cGMP signaling pathways (VASP, beta-catenin, AKT). Figure S2 shows RT-qPCR analysis of the mucosa and polyps from contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2618ac4db3630a5c307014a45937b926
https://doi.org/10.1158/1940-6207.22533029
https://doi.org/10.1158/1940-6207.22533029
Autor:
Darren D. Browning, Wonsuk Yoo, Subbaramiah Sridhar, Franklin G. Berger, Nagendra Singh, Yali Hou, Bianca N. Islam, Sarah K. Sharman
The cGMP signaling axis has been implicated in the suppression of intestinal cancers, but the inhibitory mechanism and the extent to which this pathway can be targeted remains poorly understood. This study has tested the effect of cGMP-elevating agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0f3adc1748724c741292a223cdd81e
https://doi.org/10.1158/1940-6207.c.6547064.v1
https://doi.org/10.1158/1940-6207.c.6547064.v1
Autor:
Bianca N Islam, Sarah K Sharman, Yali Hou, Rui Wang, Justin Ashby, Honglin Li, Kebin Liu, Kenneth J Vega, Darren D Browning
Publikováno v:
Carcinogenesis
A large body of evidence has demonstrated that cyclic-guanosine monophosphate (cGMP), signaling has anti-tumor effects that might be used for colon cancer prevention. The tumor-suppressive mechanism and the signaling components downstream of cGMP rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64561a8fe8d540909a0c71aad1b77318
https://doi.org/10.1093/carcin/bgac022
https://doi.org/10.1093/carcin/bgac022
Autor:
Yali Hou, Alexis Wren, Namratha Mylarapu, Kaylin Browning, Bianca N. Islam, Rui Wang, Kenneth J. Vega, Darren D. Browning
Publikováno v:
J Pharmacol Exp Ther
There is growing interest in the potential use of phosphodiesterase (PDE) inhibitors for colorectal cancer (CRC) prevention and treatment. The present study has tested the idea that PDE inhibitors inhibit growth and viability of CRC cell lines by inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71e0d6ad7bf54a2ff641cd0123731ff
https://doi.org/10.1124/jpet.121.001075
https://doi.org/10.1124/jpet.121.001075
Publikováno v:
American Journal of Gastroenterology. 117:e2078-e2078
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2559a7bd7e0f7fefd53687d2b7323d70
https://doi.org/10.14309/01.ajg.0000869692.87046.f6
https://doi.org/10.14309/01.ajg.0000869692.87046.f6
Autor:
Yafei Cai, Richard S. Blumberg, Nagendra Singh, Kebin Liu, Huabin Zhu, Guangxun Zhu, Siyang Liu, Zezheng Pan, Darren D Browning, Chunwan Lu, Candace J. Poole, Jan van Riggelen, Honglin Li, Bianca N. Islam, Michaela Quintero
Publikováno v:
Cell Discovery, Vol 5, Iss 1, Pp 1-16 (2019)
Cell Discovery
Cell Discovery
Intestinal exocrine secretory cells, including Paneth and goblet cells, have a pivotal role in intestinal barrier function and mucosal immunity. Dysfunction of these cells may lead to the pathogenesis of human diseases such as inflammatory bowel dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c68ddf4c2ff9fcf0fd6f92018135efe
http://link.springer.com/article/10.1038/s41421-018-0070-x
http://link.springer.com/article/10.1038/s41421-018-0070-x