Autosomal recessive hyposegmentation of granulocytes in Australian Shepherd Dogs indicates a role for LMBR1L in myeloid leukocytes.

Autor: Bianca Lourdes Frehner, Matthias Christen, Iris M Reichler, Vidhya Jagannathan, Marilisa Novacco, Barbara Riond, Laureen M Peters, José Suárez Sánchez-Andrade, Aldona Pieńkowska-Schelling, Claude Schelling, Anja Kipar, Tosso Leeb, Orsolya Balogh

Publikováno v: PLoS Genetics, Vol 19, Iss 6, p e1010805 (2023)

Pelger-Huët anomaly (PHA) in humans is an autosomal dominant hematological phenotype without major clinical consequences. PHA involves a characteristic hyposegmentation of granulocytes (HG). Human PHA is caused by heterozygous loss of function varia

Externí odkaz: https://doaj.org/article/e76e1fdb15e941ba9bb0d40f59f0e4a2

Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog

Autor: Iris M Reichler, Sandra Goericke-Pesch, Aykut Gram, Orsolya Balogh, Mariusz P. Kowalewski, Stefanie Keller, Bianca Lourdes Frehner

Publikováno v: Frehner, B L, Reichler, I M, Kowalewski, M P, Gram, A, Keller, S, Goericke-Pesch, S & Balogh, O 2021, ' Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog ', The Journal of reproduction and development, vol. 67, no. 3, pp. 207-215 . https://doi.org/10.1262/jrd.2020-141
The Journal of Reproduction and Development

The underlying functional and molecular changes in canine primary uterine inertia (PUI) are still not clarified. Leptin (Lep) and obesity negatively affect uterine contractility in women, partly mediated by the RhoA/Rho associated kinase pathway, aff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729e43e473a32c98b8264691e8acbcbf
https://avesis.erciyes.edu.tr/publication/details/662b1ec7-2270-4b81-993f-52be694007bb/oai