Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Bianca J J M Brundel"'
Autor:
Roelien A M Meijering, Marit Wiersma, Denise M S van Marion, Deli Zhang, Femke Hoogstra-Berends, Anne-Jan Dijkhuis, Martina Schmidt, Thomas Wieland, Harm H Kampinga, Robert H Henning, Bianca J J M Brundel
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133553 (2015)
The heat shock response (HSR) is an ancient and highly conserved program of stress-induced gene expression, aimed at reestablishing protein homeostasis to preserve cellular fitness. Cells that fail to activate or maintain this protective response are
Externí odkaz:
https://doaj.org/article/2fbf7db494df495a9a7686a920c847bd
Autor:
Myrthe F. Kuipers, Ronja Laurila, Maurice L. Remy, Michiel van Oudheusden, Nedra Hazlett, Sally Lipsky, Lianna L. Reisner, Debbe McCall, Natasja M. S. de Groot, Bianca J. J. M. Brundel
Publikováno v:
Nutrients, Vol 16, Iss 16, p 2672 (2024)
Atrial fibrillation (AF) is the most common heart rhythm disorder in the Western world. Between the years 2010 and 2019, the global prevalence of AF rose from 33.5 million to 59 million, highlighting the importance of developing equitable treatments
Externí odkaz:
https://doaj.org/article/71c2f98aff454a2390e5d47a1724b462
Autor:
Lei Ke, Roelien A M Meijering, Femke Hoogstra-Berends, Katarina Mackovicova, Michel J Vos, Isabelle C Van Gelder, Robert H Henning, Harm H Kampinga, Bianca J J M Brundel
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20395 (2011)
BackgroundWe previously demonstrated the small heat shock protein, HSPB1, to prevent tachycardia remodeling in in vitro and in vivo models for Atrial Fibrillation (AF). To gain insight into its mechanism of action, we examined the protective effect o
Externí odkaz:
https://doaj.org/article/7ceac7bc851f4a02b6f29f6b85772222
Publikováno v:
Cells, Vol 13, Iss 4, p 311 (2024)
Atrial fibrillation (AF) is the most common progressive cardiac arrhythmia worldwide and entails serious complications including stroke and heart failure. Despite decades of clinical research, the current treatment of AF is suboptimal. This is due to
Externí odkaz:
https://doaj.org/article/7e6e1ff929f94550ba73e2bd2a7195ad
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a3c013d1594947069d315d2c9fe353c5
Publikováno v:
Cells, Vol 12, Iss 18, p 2242 (2023)
Despite many efforts to treat atrial fibrillation (AF), the most common progressive and age-related cardiac tachyarrhythmia in the Western world, the efficacy is still suboptimal. A plausible reason for this is that current treatments are not directe
Externí odkaz:
https://doaj.org/article/8f11ace183704327b92d4fade155a9f4
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 13, p 4352 (2023)
Despite the many attempts to treat atrial fibrillation (AF), the most common cardiac tachyarrhythmia in the Western world, the treatment efficacy of AF is still suboptimal. A plausible reason for the suboptimal efficacy is that the current treatments
Externí odkaz:
https://doaj.org/article/3f5e90e95d4b4225950f12588fd84a54
Autor:
Mariann Gyöngyösi, Pilar Alcaide, Folkert W Asselbergs, Bianca J J M Brundel, Giovanni G Camici, Paula da Costa Martins, Péter Ferdinandy, Marianna Fontana, Henrique Girao, Massimiliano Gnecchi, Can Gollmann-Tepeköylü, Petra Kleinbongard, Thomas Krieg, Rosalinda Madonna, Melanie Paillard, Antonis Pantazis, Cinzia Perrino, Maurizio Pesce, Gabriele G Schiattarella, Joost P G Sluijter, Sabine Steffens, Carsten Tschöpe, Sophie Van Linthout, Sean M Davidson
Publikováno v:
Cardiovascular Research
Cardiovascular Research, 2022, pp.cvac115. ⟨10.1093/cvr/cvac115⟩
Gyöngyösi, M, Alcaide, P, Asselbergs, F W, Brundel, B J J M, Camici, G G, Martins, P D C, Ferdinandy, P T, Fontana, M, Girao, H, Gnecchi, M, Gollmann-Tepeköylü, C, Kleinbongard, P, Krieg, T, Madonna, R, Paillard, M, Pantazis, A, Perrino, C, Pesce, M, Schiattarella, G G, Sluijter, J P G, Steffens, S, Tschöpe, C, van Linthout, S & Davidson, S M 2023, ' Long COVID and the cardiovascular system-elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies : a joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial and Pericardial Diseases ', Cardiovascular Research, vol. 119, no. 2, pp. 336-356 . https://doi.org/10.1093/cvr/cvac115
Cardiovascular Research, 2022, pp.cvac115. ⟨10.1093/cvr/cvac115⟩
Gyöngyösi, M, Alcaide, P, Asselbergs, F W, Brundel, B J J M, Camici, G G, Martins, P D C, Ferdinandy, P T, Fontana, M, Girao, H, Gnecchi, M, Gollmann-Tepeköylü, C, Kleinbongard, P, Krieg, T, Madonna, R, Paillard, M, Pantazis, A, Perrino, C, Pesce, M, Schiattarella, G G, Sluijter, J P G, Steffens, S, Tschöpe, C, van Linthout, S & Davidson, S M 2023, ' Long COVID and the cardiovascular system-elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies : a joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial and Pericardial Diseases ', Cardiovascular Research, vol. 119, no. 2, pp. 336-356 . https://doi.org/10.1093/cvr/cvac115
Long COVID has become a world-wide, non-communicable epidemic, caused by long-lasting multiorgan symptoms that endure for weeks or months after SARS-CoV-2 infection has already subsided. This scientific document aims to provide insight into the possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72ebd91f109b8c18c32f8ea52c04cb0
https://www.ncbi.nlm.nih.gov/pubmed/35875883
https://www.ncbi.nlm.nih.gov/pubmed/35875883
Autor:
Marit Wiersma, Roelien A. M. Meijering, Xiao‐Yan Qi, Deli Zhang, Tao Liu, Femke Hoogstra‐Berends, Ody C. M. Sibon, Robert H. Henning, Stanley Nattel, Bianca J. J. M. Brundel
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundDerailment of proteostasis, the homeostasis of production, function, and breakdown of proteins, contributes importantly to the self‐perpetuating nature of atrial fibrillation (AF), the most common heart rhythm disorder in humans. Autophag
Externí odkaz:
https://doaj.org/article/dfa7a618d78241b4a8ef03cf8bfc2531
Publikováno v:
Frontiers in cell and developmental biology. 10
Desmin (DES) is a classical type III intermediate filament protein encoded by the DES gene. Desmin is abundantly expressed in cardiac, skeletal, and smooth muscle cells. In these cells, desmin interconnects several protein-protein complexes that cove