Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Bianca Fuhrman"'
Autor:
Bianca Fuhrman
Publikováno v:
Journal of Lipids, Vol 2012 (2012)
Serum paraoxonase-1 (PON1) is a member of the paraoxonases family (PON1, PON2, and PON3). PON1 is synthesized and secreted by the liver, and in circulation it is associated with HDL. PON1 has antioxidative properties, which are associated with the en
Externí odkaz:
https://doaj.org/article/ccc162c9e9cc47da93e1de523911c8bd
Autor:
Uwe Jerke, Sergey Tkachuk, Julia Kiyan, Victoria Stepanova, Angelika Kusch, Michael Hinz, Rainer Dietz, Hermann Haller, Bianca Fuhrman, Inna Dumler
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8302 (2009)
BACKGROUND:Members of the signal transducer and activator of transcription (Stat) family of transcription factors traverse the nuclear membrane through a specialized structure, called the nuclear pore complex (NPC), which represents a selective filte
Externí odkaz:
https://doaj.org/article/faa4eeef3dbd431c8303e80f4f9f83fc
Publikováno v:
BioFactors. 41:44-51
It was documented that pomegranate has anti-inflammatory effects. In this study, we investigated a direct effect of pomegranate juice (PJ) and its polyphenols on macrophage inflammatory phenotype. In vitro, PJ and its major polyphenols dose-dependent
Publikováno v:
Atherosclerosis. 231:29-38
Objective Monocyte-to-macrophage differentiation and macrophage death play a pivotal role in atherogenesis. uPA and its receptor uPAR are expressed in atherosclerotic lesion macrophages and contribute to atherosclerosis progression. In the present st
Autor:
Bianca Fuhrman
Publikováno v:
Atherosclerosis. 222:8-14
Atherogenesis refers to the development of atheromatous plaques in the inner lining of the arteries. These atherosclerotic lesions are characterized by accumulation of monocyte-derived macrophage-foam cells loaded with cholesterol, which eventually u
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:449-458
Objective— The atherosclerotic lesion is characterized by lipid peroxide accumulation. Paraoxonase 1 (PON1) reduces atherosclerotic lesion oxidative stress, whereas urokinase-type plasminogen activator (uPA) increases oxidative stress in atheroscle
Publikováno v:
Nutrition. 26:359-366
Objective The high-density lipoprotein (HDL)-associated paraoxonase-1 (PON1)/free PON1 ratio is lower in diabetic patients in comparison with healthy controls. Because diabetes is associated with increased oxidative stress, we hypothesized that a lab
Publikováno v:
Biochemical and Biophysical Research Communications. 391:523-528
Aims Diabetes is associated with atherogenesis and macrophage-foam cell formation, due in part to a decrease in HDL-mediated cholesterol efflux from macrophages. This study examined the expression of proteins involved in cholesterol transport, i.e. A
Autor:
Nirit Hanin-Avraham, Angel Porgador, Sofiya Kolusheva, Michael Aviram, Agnieszka Mech-Dorosz, Bianca Fuhrman, Raz Jelinek
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1788(11):2436-2443
Changes in the abundance and properties of blood lipoproteins are generally considered major causes for varied pathological conditions and diseases. Using novel chromatic biomimetic vesicle and cell assays, we present here for the first time evidence
Autor:
Michael Aviram, Anna Gantman, Sven Horke, Bianca Fuhrman, Nina Volkova, Jasmin Khateeb, Julia Kiyan, Inna Dumler
Publikováno v:
Cardiovascular Research. 84:145-154
Aims We have recently shown that urokinase plasminogen activator (uPA) increases oxidative stress (OS), cholesterol biosynthesis, and paraoxonase 2 (PON2) expression in macrophages via binding to its receptor, the uPAR. Since PON2 is regulated by bot