Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bianca F. van Driel"'
Autor:
Marco V. Haselager, Bianca F. van Driel, Eduard Perelaer, Dennis de Rooij, Danial Lashgari, Remco Loos, Arnon P. Kater, Perry D. Moerland, Eric Eldering
Publikováno v:
HemaSphere, Vol 7, Iss 9, p e938 (2023)
Chronic lymphocytic leukemia (CLL) cells are highly dependent on microenvironmental cells and signals. The lymph node (LN) is the critical site of in vivo CLL proliferation and development of resistance to both chemotherapy and targeted agents. We pr
Externí odkaz:
https://doaj.org/article/7bad755cafac4a3baec0ab51f9c88c15
Autor:
Karoline Kielbassa, Marco V. Haselager, Danique J. C. Bax, Bianca F. van Driel, Julie Dubois, Mark-David Levin, Sabina Kersting, Rebecka Svanberg, Carsten U. Niemann, Arnon P. Kater, Eric Eldering
Publikováno v:
Leukemia.
Chronic lymphocytic leukemia (CLL) cells upregulate Bcl-2 proteins within the lymph node (LN) microenvironment. Signaling via B-cell receptor, Toll-like receptors and CD40 collectively reduce sensitivity to the BCL-2 inhibitor venetoclax. Time-limite