Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Bianca Derrer"'
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Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins
Autor: Barbara Kappes, Joerg Seidler, Dominic Winter, Wolf D. Lehmann, Bianca Derrer, Dominik Kugelstadt
Publikováno v: PROTEOMICS. 10:1510-1514
A novel type of isobaric internal peptide standard for quantitative proteomics is described. The standard is a synthetic peptide derived from the target peptide by positional permutation of two amino acids. This type of internal standard is denominat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fb19be15212a181d617f94206be616
https://doi.org/10.1002/pmic.200900695
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3
The shikimate pathway in apicomplexan parasites: implications for drug development
Autor: Barbara Kappes, Peter Macheroux, Bianca Derrer
Publikováno v: Frontiers in bioscience (Landmark edition). 18(3)
The shikimate pathway provides basic building blocks for a variety of aromatic compounds including aromatic amino acids, ubiquinone, folate and compounds of the secondary metabolism. The seven enzymatic reactions of the pathway lead to the generation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d25824debbd6562065f82a97f15364e
https://pubmed.ncbi.nlm.nih.gov/23747859
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4
From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum
Autor: Barbara Kappes, Shaheen Ahmed, Werner Seebacher, Tai Wang, Leonardo Scapozza, Bianca Derrer, Remo Perozzo, Leonardo Lauciello
Publikováno v: Malaria Journal, Vol 11, Iss Suppl 1, p P60 (2012)
Malaria Journal
Background For several years now, Plasmodium falciparum is developing resistance to drugs in use. There is hence an urgent need for new treatments as well as new targets. By identifying the targets of novel or known active molecules with unknown mech
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907d64c5a811b5ca378217e7d5b11bc4
https://doaj.org/article/9822ca0ed2734a0ca43d1bf0a82bfeb9
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5
Molecular characterisation of a second structurally unusual AR-Smad without an MH1 domain and a Smad4 orthologue from Echinococcus multilocularis
Autor: Ricardo Zavala-Góngora, Petra Knaus, Bianca Derrer, Klaus Brehm, Verena Gelmedin
Publikováno v: International journal for parasitology. 38(2)
Members of the transforming growth factor-beta/bone morphogenetic protein (TGF-beta/BMP) family of cytokines play crucial roles in animal development and are candidate molecules for host-parasite cross-communication in helminth diseases. TGF-beta/BMP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a9457da55c023024e3e2809167da98
https://pubmed.ncbi.nlm.nih.gov/17845804
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6
Assembly of the Eukaryotic PLP-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme
Autor: Bettina Böttcher, Gabriela Guédez, Martin Gengenbacher, Volker Windeisen, Bianca Derrer, Irmgard Sinning, Katharina Hipp, Barbara Kappes, Ivo Tews
Publikováno v: Structure. (1):172-184
SUMMARY Biosynthesis of vitamins is fundamental to malaria parasites. Plasmodia synthesize the active form of vitamin B6 (pyridoxal 5 0 -phosphate, PLP) using a PLP synthase complex. The EM analysis shown here reveals a random association pattern of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6853789f6edcc957712f25d4d11736f
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