Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bianca Bloechl"'
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102809- (2024)
Summary: Here, we present a protocol to perform barcode decay lineage tracing followed by single-cell transcriptome analysis (BdLT-Seq). We describe steps for BdLT-Seq experimental design, building barcoded episome reporters, performing episome trans
Externí odkaz:
https://doaj.org/article/bd6ed260d81147a9b580e810e436c877
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Cellular plasticity is a core biological process; however, observing diversity in non-genetic inheritance and the resulting phenotypic outputs, is challenging. Here the authors develop a non-genetically based tracing technology which can be used to r
Externí odkaz:
https://doaj.org/article/56fdd941f5ec4fe7bc8b400f5cc61b18
Autor:
Tatyana B. Nesterova, Guifeng Wei, Heather Coker, Greta Pintacuda, Joseph S. Bowness, Tianyi Zhang, Mafalda Almeida, Bianca Bloechl, Benoit Moindrot, Emma J. Carter, Ines Alvarez Rodrigo, Qi Pan, Ying Bi, Chun-Xiao Song, Neil Brockdorff
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Xist RNA is the master regulator of X chromosome inactivation. Here the authors describe a systematic analysis of Xist-mediated allelic silencing in mouse ESC models and define the contribution of different pathways that regulate gene silencing.
Externí odkaz:
https://doaj.org/article/1099fcaec9864035a2a87b2701f1ba55
Autor:
Kathy-Ann Secker, Bianca Bloechl, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, Dominik Schneidawind, Johan Jeong, Thomas Hentrich, Julia M. Schulze-Hentrich, Corina Schneidawind
Publikováno v:
Cancers
Volume 12
Issue 5
Cancers, Vol 12, Iss 1342, p 1342 (2020)
Volume 12
Issue 5
Cancers, Vol 12, Iss 1342, p 1342 (2020)
Epigenetic dysregulation plays a pivotal role in mixed-lineage leukemia (MLL) pathogenesis, therefore serving as a suitable therapeutic target. S-adenosylmethionine (SAM) is the universal methyl donor in human cells and is synthesized by methionine a
Autor:
Chun-Xiao Song, Neil Brockdorff, Bianca Bloechl, Benoit Moindrot, Qi Pan, Guifeng Wei, Greta Pintacuda, Ying Bi, Heather Coker, Ines Alvarez Rodrigo, Joseph S Bowness, Emma J. Carter, Tatyana B. Nesterova, Tianyi Zhang, Mafalda Almeida
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Xist RNA, the master regulator of X chromosome inactivation, acts in cis to induce chromosome-wide silencing. Whilst recent studies have defined candidate silencing factors, their relative contribution to repressing different genes, and their relatio