Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bianca, Crifo"'
Autor:
Robbe Saesen, Matilde Machado, Bianca Crifo, Lifang Liu, Corinne de Vries, Ralf Herold, Jordi Llinares Garcia, Isabelle Huys
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundThe European Medicines Agency (EMA) interacts with many different stakeholders involved in the development of drugs, including academic researchers. In recent years, EMA has collaborated more closely with academia, inter alia by taking part
Externí odkaz:
https://doaj.org/article/ec20d80ae9b94c39b26358493e16d82c
Autor:
Bianca Crifo, Wallace K. MacNaughton
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 322:G169-G182
Mucosal and histological healing have become the gold standards for assessing the efficacy of therapy in patients living with inflammatory bowel diseases (IBD). Despite these being the accepted goals in therapy, the mechanisms that underlie the heali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5837ce73d37cd4f3c46a5900022d07
https://doi.org/10.1152/ajpgi.00194.2021
https://doi.org/10.1152/ajpgi.00194.2021
Autor:
Caitríona Hickey, Bettina Schaible, Scott Nguyen, Daniel Hurley, Shabarinath Srikumar, Séamus Fanning, Eric Brown, Bianca Crifo, David Matallanas, Siobhán McClean, Cormac T. Taylor, Kirsten Schaffer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
The factors influencing the virulence of P. aeruginosa in the development of invasive infection remain poorly understood. Here, we investigated the role of the host microenvironment in shaping pathogen virulence and investigated the mechanisms involv
Externí odkaz:
https://doaj.org/article/adcaf4dce143402196a01b3f82dae03e
Autor:
Carsten C Scholz, Javier Rodriguez, Christina Pickel, Stephen Burr, Jacqueline-Alba Fabrizio, Karen A Nolan, Patrick Spielmann, Miguel A S Cavadas, Bianca Crifo, Doug N Halligan, James A Nathan, Daniel J Peet, Roland H Wenger, Alex Von Kriegsheim, Eoin P Cummins, Cormac T Taylor
Publikováno v:
PLoS Biology, Vol 14, Iss 1, p e1002347 (2016)
The asparagine hydroxylase, factor inhibiting HIF (FIH), confers oxygen-dependence upon the hypoxia-inducible factor (HIF), a master regulator of the cellular adaptive response to hypoxia. Studies investigating whether asparagine hydroxylation is a g
Externí odkaz:
https://doaj.org/article/195eb6b4e4534a8d981fea77cbdb36dd
Publikováno v:
Journal of Biological Chemistry. 295:1195-1201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6ef4837c981bbd896e5a82f38d94780
https://doi.org/10.1016/s0021-9258(17)49879-6
https://doi.org/10.1016/s0021-9258(17)49879-6
Publikováno v:
Journal of Biological Chemistry. 295:1195-1201
Pseudomonas aeruginosa is an extracellular opportunistic bacterial pathogen commonly associated with infectious complications in susceptible individuals, such as those with underlying diseases including HIV/AIDS and cystic fibrosis. Antibiotic resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd8c1371f5dca28d824544da4762fdb1
https://doi.org/10.1074/jbc.ra119.010033
https://doi.org/10.1074/jbc.ra119.010033
Publikováno v:
J Biol Chem
Pseudomonas aeruginosa is an extracellular opportunistic bacterial pathogen commonly associated with infectious complications in susceptible individuals, such as those with underlying diseases including HIV/AIDS and cystic fibrosis. Antibiotic resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7870648114a814352002576f106e982
https://pubmed.ncbi.nlm.nih.gov/31826919
https://pubmed.ncbi.nlm.nih.gov/31826919
Autor:
Domiziana De Tommaso, Cosima T. Baldari, Mattia Criscuoli, Bianca Crifo, Sara Monaci, Fabio Carraro, Cormac T. Taylor, Irene Filippi, Antonella Naldini, Giuditta Guerrini, Giuliana Pelicci, Cristina Ulivieri
Publikováno v:
Journal of cellular physiologyREFERENCES. 235(11)
Hypoxia occurs in physiological and pathological conditions. T cells experience hypoxia in pathological and physiological conditions as well as in lymphoid organs. Indeed, hypoxia-inducible factor 1α (HIF-1α) affects T cell survival and functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d001843b624cac48246b85eb5e5a375
https://pubmed.ncbi.nlm.nih.gov/31944299
https://pubmed.ncbi.nlm.nih.gov/31944299
Autor:
Daniel Crean, Antonella Naldini, Carsten C. Scholz, Bettina Schaible, Zsolt Fábián, Helen M. Roche, Susan F. Fitzpatrick, Hugh E. Giffney, Doug N. Halligan, Bianca Crifo, Alfonso Blanco, Anna M. Kirwan, Miguel Cavadas, Mattia Criscuoli, Eoin P. Cummins, Eric Brown, Cormac T. Taylor
Hypoxia is a common and prominent feature of the microenvironment at sites of bacteria-associated inflammation in inflammatory bowel disease. The prolyl-hydroxylases (PHD1/2/3) and the asparaginyl-hydroxylase factor-inhibiting HIF are oxygen-sensing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d39b33c612dbb0718e36ea61dfc5a5
https://www.zora.uzh.ch/id/eprint/169137/
https://www.zora.uzh.ch/id/eprint/169137/
Autor:
Praveen Radhakrishnan, Laura Casals-Diaz, Moritz J. Strowitzki, Martin Schneider, Eric Brown, Cormac T. Taylor, Leila Smith, Bianca Crifo, Stephen J.E. Murphy, Martin Steinhoff, Ellen H. van den Bogaard, Raphael R. Fagundes, Doug N. Halligan, Hanna Niehues, Mario C. Manresa
Publikováno v:
Allergy, 74, 753-766
Allergy, 74(4), 753-766. Wiley-Blackwell
Allergy, 74, 4, pp. 753-766
Allergy, 74(4), 753-766. Wiley-Blackwell
Allergy, 74, 4, pp. 753-766
Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. The hypoxia‐inducible factor‐1α (HIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4f9ae7f987c73233c85b75f12db898
http://hdl.handle.net/2066/202595
http://hdl.handle.net/2066/202595