Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Bianca, Altvater"'
Autor:
Silke Jamitzky, Bianca Altvater, Carolin Krekeler, Laura Hoen, Caroline Brandes, Julia Ebbinghaus, Lisa Richter, Lisa Kosel, Laurin Ochs, Nicole Farwick, Katja Urban, Lena Kluge, Lara Bücker, Dennis Görlich, Ian C. D. Johnston, Rita Pfeifer, Wolfgang Hartmann, Claudia Rossig, Sareetha Kailayangiri
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Carbohydrate markers of immature cells during prenatal human development can be aberrantly expressed in cancers and deserve evaluation as immune targets. A candidate target in Ewing sarcoma is the globo-series ganglioside stage-specific embr
Externí odkaz:
https://doaj.org/article/c7a03da52b4a4a629ef2068b60b10500
Autor:
Sareetha Kailayangiri, Bianca Altvater, Nicole Farwick, Jutta Meltzer, Wolfgang Hartmann, Claudia Rossig
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103199- (2024)
Summary: The detection of disialoganglioside GD2 on tumor biopsies, especially in paraffin-embedded tissues, has been challenging due to the glycolipid structure of GD2 and its membrane anchorage. Here, we present an immunofluorescence protocol for t
Externí odkaz:
https://doaj.org/article/6e27c866a2b14a24a2b2706fc20cf9d4
Autor:
Wolfgang Glienke, Anna Christina Dragon, Katharina Zimmermann, Alexandra Martyniszyn-Eiben, Mira Mertens, Hinrich Abken, Claudia Rossig, Bianca Altvater, Krasimira Aleksandrova, Lubomir Arseniev, Christina Kloth, Andriana Stamopoulou, Thomas Moritz, Holger N. Lode, Nikolai Siebert, Rainer Blasczyk, Lilia Goudeva, Axel Schambach, Ulrike Köhl, Britta Eiz-Vesper, Ruth Esser
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chimeric antigen receptor (CAR)-engineered T cells can be highly effective in the treatment of hematological malignancies, but mostly fail in the treatment of solid tumors. Thus, approaches using 4th advanced CAR T cells secreting immunomodulatory cy
Externí odkaz:
https://doaj.org/article/0a0e47512e424a90ba1c2e5115780b13
Autor:
Loreen Sophie Rudek, Katharina Zimmermann, Melanie Galla, Johann Meyer, Johannes Kuehle, Andriana Stamopoulou, Daniel Brand, I. Erol Sandalcioglu, Belal Neyazi, Thomas Moritz, Claudia Rossig, Bianca Altvater, Christine S. Falk, Hinrich Abken, Michael Alexander Morgan, Axel Schambach
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immune cell therapeutics are increasingly applied in oncology. Especially chimeric antigen receptor (CAR) T cells are successfully used to treat several B cell malignancies. Efforts to engineer CAR T cells for improved activity against solid tumors i
Externí odkaz:
https://doaj.org/article/2a54408c3f4a4724be8b0023202931c6
Autor:
Malena Wiebel, Sareetha Kailayangiri, Bianca Altvater, Jutta Meltzer, Kay Grobe, Sabine Kupich, Claudia Rossig
Publikováno v:
Cancer Reports, Vol 4, Iss 5, Pp n/a-n/a (2021)
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy of pediatric sarcomas is challenged by the paucity of targetable cell surface antigens. A candidate target in osteosarcoma (OS) is the ganglioside GD2, but heterogeneous expression
Externí odkaz:
https://doaj.org/article/782e6053cd61477eb41e9f9928394a21
Autor:
Marcel Trautmann, Ya‐Yun Cheng, Patrizia Jensen, Ninel Azoitei, Ines Brunner, Jennifer Hüllein, Mikolaj Slabicki, Ilka Isfort, Magdalene Cyra, Ruth Berthold, Eva Wardelmann, Sebastian Huss, Bianca Altvater, Claudia Rossig, Susanne Hafner, Thomas Simmet, Anders Ståhlberg, Pierre Åman, Thorsten Zenz, Undine Lange, Thomas Kindler, Claudia Scholl, Wolfgang Hartmann, Stefan Fröhling
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 5, Pp 1-15 (2019)
Abstract Myxoid liposarcomas (MLS), malignant tumors of adipocyte origin, are driven by the FUS‐DDIT3 fusion gene encoding an aberrant transcription factor. The mechanisms whereby FUS‐DDIT3 mediates sarcomagenesis are incompletely understood, and
Externí odkaz:
https://doaj.org/article/f108c740f7c147e7996dd3f7e34308ef
Autor:
Wolfgang Hartmann, Sebastian Huss, Eva Wardelmann, Pierre Åman, Jessica Becker, Thomas Simmet, Susanne Hafner, Claudia Rossig, Bianca Altvater, Konrad Steinestel, Inga Grünewald, Arne Krüger, Birte Jeiler, Ilka Isfort, Magdalene Cyra, Marcel Trautmann
Myxoid liposarcoma (MLS) is an aggressive soft-tissue tumor characterized by a specific reciprocal t(12;16) translocation resulting in expression of the chimeric FUS–DDIT3 fusion protein, an oncogenic transcription factor. Similar to other transloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e2be92ae79f97e822effef90988d24b
https://doi.org/10.1158/1535-7163.c.6537922.v1
https://doi.org/10.1158/1535-7163.c.6537922.v1
Autor:
Wolfgang Hartmann, Sebastian Huss, Eva Wardelmann, Pierre Åman, Jessica Becker, Thomas Simmet, Susanne Hafner, Claudia Rossig, Bianca Altvater, Konrad Steinestel, Inga Grünewald, Arne Krüger, Birte Jeiler, Ilka Isfort, Magdalene Cyra, Marcel Trautmann
Supplementary Table S1: Clinicopathological characteristics of patients with myxoid liposarcoma (n=56) including semi-quantitative immunohistochemistry and mutational analyses results. Supplemental Table S2: Gene list. Supplementary Table S3: In sili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28395882e925867546c8eef441fd1d0c
https://doi.org/10.1158/1535-7163.22504987.v1
https://doi.org/10.1158/1535-7163.22504987.v1
Autor:
Wolfgang Hartmann, Sebastian Huss, Eva Wardelmann, Pierre Åman, Jessica Becker, Thomas Simmet, Susanne Hafner, Claudia Rossig, Bianca Altvater, Konrad Steinestel, Inga Grünewald, Arne Krüger, Birte Jeiler, Ilka Isfort, Magdalene Cyra, Marcel Trautmann
Supplementary Figure S1: In vitro and in vivo evaluation of PI3K suppression (LY294002) in myxoid liposarcoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c5f6c811e6ff156e3fe58abe446ae2
https://doi.org/10.1158/1535-7163.22504996.v1
https://doi.org/10.1158/1535-7163.22504996.v1
Autor:
Claudia Rossig, Martin Pule, Heribert Juergens, Dario Campana, Sareetha Kailayangiri, Katharina Schweer, Jaane Temme, Sibylle Pscherer, Silke Landmeier, Bianca Altvater
CCR Translation for the Article from 2B4 (CD244) Signaling by Recombinant Antigen-specific Chimeric Receptors Costimulates Natural Killer Cell Activation to Leukemia and Neuroblastoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d83124e7a6c5fef56d9a13eee7173e4
https://doi.org/10.1158/1078-0432.22441602.v1
https://doi.org/10.1158/1078-0432.22441602.v1