Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Bian-Sheng Ji"'
Autor:
Wei-wei Huang, Juan Cen, Chaojie Wang, Yuan-yuan Xie, Bian-Sheng Ji, Ying Gan, Na Zhao, Lu Liu
Publikováno v:
European Journal of Pharmacology. 844:165-174
Previous research showed N1-(quinolin-2-ylmethy) butane-1, 4-diamine (QMA), a polyamine analogue, was efficacious in the prevention of oxidative injury in models of cerebral ischemia. The present study manifested that pretreatment with QMA attenuated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb91b95c98d85c74a0563cda8be6b669
https://doi.org/10.1016/j.ejphar.2018.12.015
https://doi.org/10.1016/j.ejphar.2018.12.015
Autor:
Juan Cen, Fei Wang, Jinhua Li, Jianbin Li, Dahuan Zhang, Yong Man, Bian-Sheng Ji, Xiaoming Wang, Lu Liu, Ji Ma
Publikováno v:
Neuroscience. 369:314-324
Accumulated evidence displayed that transplantation of stem cells may be a promising approach for the treatment of neurological disorders. However, the underlying mechanisms remain to be well elucidated. Moreover, some investigators cannot reproduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d7b1b8e9b6c88a4410048c6abc590a
https://doi.org/10.1016/j.neuroscience.2017.11.027
https://doi.org/10.1016/j.neuroscience.2017.11.027
Publikováno v:
European Journal of Pharmacology. 880:173189
P-glycoprotein (P-gp) is located on the luminal surface of brain vascular endothelium and its status may determine the delivery of the agents into the brain tissues. Previous study showed that upregulation of P-gp at the blood-brain barrier (BBB) aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e955aab2266086f46f24121ed45345
https://doi.org/10.1016/j.ejphar.2020.173189
https://doi.org/10.1016/j.ejphar.2020.173189
Publikováno v:
Chemico-Biological Interactions. 239:139-145
P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) in tumor cells is still a main obstacle for the chemotherapeutic treatment of cancers. Thus, development of effective MDR reversing agents is an important approach in the clinic. The present s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daab0579f1556309461e5efb42cc687b
https://doi.org/10.1016/j.cbi.2015.07.003
https://doi.org/10.1016/j.cbi.2015.07.003
Publikováno v:
Journal of Chemotherapy. 25:347-354
Our previous study reported CJY, an isoflavone, can reverse P-glycoprotein (P-gp) efflux activity in rat brain microvessel endothelial cells (RBMECs). In the present report, by assessment of ATPase activity of RBMECs, we gained further insight into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3489f95192913a4d278d2414ff12adf7
https://doi.org/10.1179/1973947813y.0000000094
https://doi.org/10.1179/1973947813y.0000000094
Publikováno v:
International Journal of Developmental Neuroscience. 31:828-835
It has been commonly recognized that accumulated amyloid-β (Aβ) in the brain plays a crucial role in the pathogenesis of Alzheimer's disease (AD). Since the deficiency of the P-glycoprotein (P-gp) at the blood-brain barrier (BBB) in AD may aggravat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793bfc79a8a70d3ffae7d2fce536e576
https://doi.org/10.1016/j.ijdevneu.2013.10.005
https://doi.org/10.1016/j.ijdevneu.2013.10.005
Publikováno v:
Chemico-biological interactions. 262
There were accumulated evidences that agents may attenuate neurological disorders through a hormetic effect. This study was designed to investigate hormetic effect of BME on the oxygen-glucose deprivation (OGD)-induced mitochondrial apoptosis in NGF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2710aa98aca12913cafd3387cafa6e0f
https://pubmed.ncbi.nlm.nih.gov/27923643
https://pubmed.ncbi.nlm.nih.gov/27923643
Publikováno v:
Drug Development Research. 73:11-17
It is widely recognized that glutamate (Glu)-induced cytotoxicity, intracellular calcium overload and the excessive free radical production are key events in the development and progression of ischemic brain injury. dl-3-n-butylphthalide (NBP), an an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c1012eda266b729d56a170af281d0d
https://doi.org/10.1002/ddr.20444
https://doi.org/10.1002/ddr.20444
Publikováno v:
Journal of Organometallic Chemistry. 696:852-858
Four diorganotin(IV) complexes [(Me)2Sn(L1)(CH3COO)]·CH3CH2OH (1), [(Ph)2Sn(L1)(CH3COO)]·CH3CH2OH (2), [(Me)2Sn(L2)Cl] (3) and [(Ph)2Sn(L2)(CH3COO)] (4) where HL1 = 2-benzoylpyridine N(4)-phenylthiosemicarbazone and HL2 = 2-acetylpyrazine N(4)-phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f0ac8e2018d98e14a7f724975eb9af
https://doi.org/10.1016/j.jorganchem.2010.10.011
https://doi.org/10.1016/j.jorganchem.2010.10.011
Publikováno v:
Drug Development Research. 72:305-309
In the effort to inhibit P-glycoprotein (P-gp) efflux function with greater activity and less side effect, the combined effect of pair CJZ3 and verapamil (Ver) was evaluated isobolographically in numerous fixed-ratio combinations of 1:1, 1:2, 1:4, 1:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c49eacb587d5a367c9088e434d7fb0
https://doi.org/10.1002/ddr.20430
https://doi.org/10.1002/ddr.20430