NAT1 genetic variation increases asthma risk in children with secondhand smoke exposure.

Autor: Brooks CC; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Martin LJ; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA., Pilipenko V, He H; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., LeMasters GK; Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA., Lockey JE; Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA., Bernstein DI; Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA., Ryan PH; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA., Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA., Biagini Myers JM; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.

Publikováno v: The Journal of asthma : official journal of the Association for the Care of Asthma [J Asthma] 2021 Mar; Vol. 58 (3), pp. 284-292. Date of Electronic Publication: 2019 Dec 06.

Weighing in on asthma: Insights on BMI, magnesium, and hospitalizations from the Ohio Pediatric Asthma Repository.

Autor: Schuler CL; Division of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Biagini Myers JM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Kercsmar CM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Pilipenko VV; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Kroner JW; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Simmons JM; Division of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Austin SR; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Gunkelman SM; Division of Pediatric Hospital Medicine, Akron Children's Hospital, Akron, OH, USA., Ross KR; Department of Pediatrics-Pulmonary, Rainbow Babies and Children's Hospital, Cleveland, OH, USA., McCoy KS; Division of Pediatric Pulmonology, Nationwide Children's Hospital, Columbus, OH, USA., Kalra M; Department of Pulmonary Medicine, Dayton Children's Hospital, Dayton, OH, USA., Ruddy JR; Department of Pediatric Pulmonary Medicine, ProMedica Toledo Children's Hospital, Toledo, OH, USA., Martin LJ; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Khurana Hershey GK; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Publikováno v: The Journal of asthma : official journal of the Association for the Care of Asthma [J Asthma] 2020 Dec; Vol. 57 (12), pp. 1280-1287. Date of Electronic Publication: 2019 Aug 14.

Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk.

Autor: Stevens ML; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Zhang Z; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Johansson E; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Ray S; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Jagpal A; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Ruff BP; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Kothari A; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., He H; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Martin LJ; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Ji H; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Wikenheiser-Brokamp K; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA.; Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Weirauch MT; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA.; Division of Center for Autoimmune Genomics and Etiology, , Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Supp DM; Research Department, Shriners Hospitals for Children, Cincinnati, OH, 45229, USA.; Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, 45221, USA., Biagini Myers JM; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA. Gurjit.Hershey@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA. Gurjit.Hershey@cchmc.org.

Publikováno v: Nature communications [Nat Commun] 2020 Aug 14; Vol. 11 (1), pp. 4092. Date of Electronic Publication: 2020 Aug 14.

Use of the Pediatric Asthma Risk Score to predict allergic and nonallergic asthma.

Autor: Schauberger E; Division of Pediatric Allergy, Immunology, and Rheumatology, University of Wisconsin, Madison, Wisconsin., Biagini Myers JM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Asthma Research, Cincinnati Children's Hospital, Cincinnati, Ohio., He H; Division of Human Genetics, Cincinnati Children's Hospital, Cincinnati, Ohio., Martin LJ; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Human Genetics, Cincinnati Children's Hospital, Cincinnati, Ohio., Arshad SH; David Hide Asthma & Allergy Research Centre, St. Mary's Hospital NHS Trust, Newport, United Kingdom., Kurukulaaratchy R; David Hide Asthma & Allergy Research Centre, St. Mary's Hospital NHS Trust, Newport, United Kingdom., Khurana Hershey GK; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Asthma Research, Cincinnati Children's Hospital, Cincinnati, Ohio. Electronic address: gurjit.hershey@cchmc.org.

Publikováno v: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2020 Jun; Vol. 124 (6), pp. 629-631.e2. Date of Electronic Publication: 2020 Mar 20.

Age and early maternal smoking contribute to epithelial cell IL-13 responsiveness in a pediatric asthma population.

Autor: McAlees JW; The Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Baker T; The Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Kaur D; The Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., McKnight C; The Division of Allergy, Immunology and Rheumatology, University of Cincinnati, Cincinnati, Ohio.; Medical Service, Cincinnati Veteran's Administration, Cincinnati, Ohio., Lindsley A; The Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; The Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio., Strait RT; The Department of Emergency Medicine, Dayton Children's Hospital, Dayton, Ohio., Zhang X; The Department of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Biagini Myers JM; The Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; The Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio., Butsch Kovacic M; The Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; The Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio.; The College of Allied Health Sciences, University of Cincinnati, Cincinnati, Ohio., Lewkowich IP; The Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; The Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio.

Publikováno v: Allergy [Allergy] 2019 Dec; Vol. 74 (12), pp. 2485-2487. Date of Electronic Publication: 2019 Jul 02.