Hypertrophic Chondrocytes Have a Limited Capacity to Cope with Increases in Endoplasmic Reticulum Stress without Triggering the Unfolded Protein Response

Autor: M. Helen Rajpar, Louise H. W. Kung, Raymond P. Boot-Handford, Michael D. Briggs

Publikováno v: Journal of Histochemistry and Cytochemistry

Mutations causing metaphyseal chondrodysplasia type Schmid (MCDS) (e.g., Col10a1p.N617K) induce the pathology by a mechanism involving increased endoplasmic reticulum (ER) stress triggering an unfolded protein response (UPR) in hypertrophic chondrocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28050073abc402eac52d90c543a5aca8
https://doi.org/10.1369/0022155412458436

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Glucose-regulated protein 78 regulates the subunit-folding of the CCT complex by modulating gene expression and protein interaction in the microsporidian Nosema bombycis.

Autor: Xu S; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China., Xiao S; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China., Qi J; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China., Yao M; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China., He P; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China., Wang R; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China., Wei E; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China., Wang Q; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China; Sericulture Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang, People's Republic of China., Zhang Y; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China; Sericulture Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang, People's Republic of China., Tang X; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China; Sericulture Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang, People's Republic of China., Shen Z; Jiangsu University of Science and Technology, Zhenjiang, People's Republic of China; Sericulture Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang, People's Republic of China. Electronic address: szysri@163.com.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2024 Dec 19; Vol. 290, pp. 138971. Date of Electronic Publication: 2024 Dec 19.

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