Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bi-yu Yuan"'
Publikováno v:
Peptides. 106:96-101
For clinical use, it is essential to develop potent endomorphin (EM) analogs with reduced antinociceptive tolerance. In the present study, the antinociceptive activities and tolerance development of four potent EM-1 analogs with C-terminal oligoargin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f8d9623ac703d767842e6b2ccb7a6a
https://doi.org/10.1016/j.peptides.2018.07.004
https://doi.org/10.1016/j.peptides.2018.07.004
Publikováno v:
Peptides. 99:128-133
Previously, we have demonstrated that endomorphins (EMs) analogs with C-terminal hydrazide modification retained the μ-opioid receptor affinity and selectivity, and exhibited potent antinociception after intracerebroventricular (i.c.v.) administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b96dfede4b8eb649d399c40c3ea47b4
https://doi.org/10.1016/j.peptides.2017.08.009
https://doi.org/10.1016/j.peptides.2017.08.009
Publikováno v:
Neuropharmacology. 116
C-terminal esterification of opioid peptides may change their opioid activities due to the modified physicochemical properties. In the present study, the pharmacological activities of C-terminal esterified endomorphin-2 (EM-2) analogs 1–3 were char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51018d6fe80960f6b3aad2afa22cc97d
https://pubmed.ncbi.nlm.nih.gov/28042019
https://pubmed.ncbi.nlm.nih.gov/28042019
Publikováno v:
Anesthesia & Analgesia; Dec2017, Vol. 125 Issue 6, p2123-2133, 11p