Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Bi-Tao Bu"'
Autor:
Dai-Shi Tian, Chuan Qin, Ming-Hao Dong, Michael Heming, Luo-Qi Zhou, Wen Wang, Song-Bai Cai, Yun-Fan You, Ke Shang, Jun Xiao, Di Wang, Chun-Rui Li, Min Zhang, Bi-Tao Bu, Gerd Meyer zu Hörste, Wei Wang
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 966-987 (2024)
Abstract B-cell maturation antigen (BCMA), expressed in plasmablasts and plasma cells, could serve as a promising therapeutic target for autoimmune diseases. We reported here chimeric antigen receptor (CAR) T cells targeting BCMA in two patients with
Externí odkaz:
https://doaj.org/article/bbc6bbd3f3864e94abcc50e72aa7cf93
Autor:
Chuan Qin, Dai-Shi Tian, Luo-Qi Zhou, Ke Shang, Liang Huang, Ming-Hao Dong, Yun-Fan You, Jun Xiao, Ying Xiong, Wen Wang, Hao Pang, Jing-Jing Guo, Song-Bai Cai, Di Wang, Chun-Rui Li, Min Zhang, Bi-Tao Bu, Wei Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Chimeric antigen receptor (CAR) T-cell therapy that targets B-cell maturation antigen (BCMA) have great potentials in autoimmune diseases and could be novel therapeutics for relapsed/refractory neuromyelitis optica spectrum disorder (NMOSD).
Externí odkaz:
https://doaj.org/article/1eb0bdae0281405d8d2cb3547cd24f23
Autor:
Xue Ma, Chuan Qin, Man Chen, Hai-Han Yu, Yun-Hui Chu, Ting-Jun Chen, Dale B. Bosco, Long-Jun Wu, Bi-Tao Bu, Wei Wang, Dai-Shi Tian
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background and purpose Neuromyelitis optica spectrum disorder (NMOSD) is mainly an anti-aquaporin 4 (anti-AQP4) autoantibodies-mediated idiopathic inflammatory demyelinating disease of the central nervous system. Systemic and local inflammat
Externí odkaz:
https://doaj.org/article/d6125d86adc2466b9cb065e8501a3213
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Purpose of reviewThis review aims to describe clinical and histological features, treatment, and prognosis in patients with anti-signal recognition particle (SRP) autoantibodies positive immune-mediated necrotizing myopathy (SRP-IMNM) based on previo
Externí odkaz:
https://doaj.org/article/c541ca259a074c078861cf5c1a5571d2
Autor:
Xue Ma, Hua-Jie Gao, Qing Zhang, Meng-Ge Yang, Zhua-Jin Bi, Su-Qiong Ji, Yue Li, Li Xu, Bi-Tao Bu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Objectives: Endoplasmic reticulum (ER) stress plays pivotal roles in the regulation of skeletal muscle damage and dysfunction in multiple disease conditions. We postulate the activation of ER stress in idiopathic inflammatory myopathies (IIM).Methods
Externí odkaz:
https://doaj.org/article/f9911fa9addf4857a92e02c596c57e7d
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundDemyelination diseases are complex puzzles that are not always straightforward to diagnose. Multiple sclerosis and neuromyelitis optica are two that are frequently encountered. Numerous autoantibodies newly discovered in recent years have s
Externí odkaz:
https://doaj.org/article/c069849c6ae64683992c4952a00ddb3a
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The changes in the serum levels of aquaporin-4-IgG (AQP4-IgG), immunoglobulins, and inflammatory mediators in neuromyelitis optica spectrum disorder (NMOSD) cases treated with immunoadsorption have been rarely described in detail. Here we report a 29
Externí odkaz:
https://doaj.org/article/1e3fc6100f074ea3a301263d196e0729
Autor:
Chuan Qin, Ran Tao, Shuo-Qi Zhang, Bo Chen, Man Chen, Hai-Han Yu, Yun-Hui Chu, Ke Shang, Long-Jun Wu, Bi-Tao Bu, Dai-Shi Tian
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
High-dose steroids, the first-line therapy for acute attacks in neuromyelitis optica spectrum disorder (NMOSD), were ineffective in a proportion of NMOSD attacks. This study aimed to explore possible predictors of high-dose steroid resistance. Demogr
Externí odkaz:
https://doaj.org/article/ab11ce1a382745f595373110596eeaef
Autor:
Wei Qiu, De-Hui Huang, Shi-Fang Hou, Mei-Ni Zhang, Tao Jin, Hui-Qing Dong, Hua Peng, Chao-Dong Zhang, Gang Zhao, Yi-Ning Huang, Dong Zhou, Wei-Ping Wu, Bao-Jun Wang, Ji-Mei Li, Xing-Hu Zhang, Yan Cheng, Hai-Feng Li, Ling Li, Chuan-Zhen Lu, Xu Zhang, Bi-Tao Bu, Wan-Li Dong, Dong-Sheng Fan, Xue-Qiang Hu, Xian-Hao Xu, for the TOWER Trial Chinese Group
Publikováno v:
Chinese Medical Journal, Vol 131, Iss 23, Pp 2776-2784 (2018)
Background: Disease-modifying therapy is the standard treatment for patients with multiple sclerosis (MS) in remission. The primary objective of the current analysis was to assess the efficacy and safety of two teriflunomide doses (7 mg and 14 mg) in
Externí odkaz:
https://doaj.org/article/0ff180c0736a4dd69098cf0ab51b4796
Publikováno v:
Brain Sciences, Vol 12, Iss 1, p 69 (2021)
As the oligoclonal band in the cerebrospinal fluid (CSF-OCB) in predicting relapsing-remitting multiple sclerosis (RRMS) is less sensitive in Asian populations than that in westerners, it remains elusive whether the IgG index could serve as an altern
Externí odkaz:
https://doaj.org/article/ad6ec972afc14ec2864c2e6b0fcfe8bc