Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Bi-Ing Chang"'
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-16 (2022)
Abstract Background Tumor vascular mimicry is an emerging issue that affects patient survival while having no treatment at the current moment. Despite several factors implicated in vascular mimicry, little is known about stromal factors that modulate
Externí odkaz:
https://doaj.org/article/6ba5ba649f974c239476698f730da5da
Autor:
Chao-Han Lai, Kuan-Chieh Wang, Fang-Tzu Lee, Hung-Wen Tsai, Chih-Yuan Ma, Tsung-Lin Cheng, Bi-Ing Chang, Yu-Jen Yang, Guey-Yueh Shi, Hua-Lin Wu
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146565 (2016)
Toll-like receptor (TLR) family plays a key role in innate immunity and various inflammatory responses. TLR4, one of the well-characterized pattern-recognition receptors, can be activated by endogenous damage-associated molecular pattern molecules su
Externí odkaz:
https://doaj.org/article/03e2820578674d28b5f8c1549945456c
Autor:
Tsung-Lin Cheng, Chao-Han Lai, Shinn-Jong Jiang, Jui-Hsiang Hung, Shi-Kai Liu, Bi-Ing Chang, Guey-Yueh Shi, Hua-Lin Wu
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Anoikis resistance allows metastatic tumor cells to survive in a homeless environment. Activation of epithelial growth factor receptor (EGFR) signaling is one of the key mechanisms for metastatic tumor cells to resist anoikis, yet the regulation mech
Externí odkaz:
https://doaj.org/article/435b8a5c33964d7c8a28b5aaff3963a5
Autor:
Yuan-Chung Kao, Shinn-Jong Jiang, Wen-An Pan, Kuan-Chieh Wang, Po-Ku Chen, Hsi-Ju Wei, Wei-Sheng Chen, Bi-Ing Chang, Guey-Yueh Shi, Hua-Lin Wu
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51647 (2012)
Human CD93, an epidermal growth factor (EGF)-like domain containing transmembrane protein, is predominantly expressed in the vascular endothelium. Studies have shown that AA4, the homolog of CD93 in mice, may mediate cell migration and angiogenesis i
Externí odkaz:
https://doaj.org/article/d8c9d25ec265409f97edcccd349f3627
Autor:
Yi-Kai Hong, Tsung-Lin Cheng, Chao-Kai Hsu, Fang-Tzu Lee, Bi-Ing Chang, Kuan-Chieh Wang, Lan-Yun Chang, Hua-Lin Wu, Chao-Han Lai
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 21 Issue 10, p3691-3709, 19p
Autor:
Shang-En Huang, Cheng-Hsiang Kuo, Si-Yu Shiao, Chia-Rui Shen, Fang-Tzu Lee, Bi-Ing Chang, Jong-Hau Hsu, Hua-Lin Wu, Jwu-Lai Yeh, Chao-Han Lai
Publikováno v:
Theranostics; 2023, Vol. 13 Issue 12, p4059-4078, 20p
Publikováno v:
Journal of periodontologyREFERENCES. 92(11)
Background Evidence demonstrates that the thrombomodulin (TM) lectin domain (TMD1) exerts anti-inflammatory functions. Lipopolysaccharides derived from Porphyromonas gingivalis (Pg-LPS) are considered a major pathogenic factor for chronic periodontit
Autor:
Cheng Hsiang Kuo, Tai Tzu Hsieh, Guey Yueh Shi, Yu Ching Huang, Hua Lin Wu, Meng Chen Sung, Po Ku Chen, Chia Fong Cho, Fang Tzu Lee, Yi-Heng Li, Chwan Yau Luo, Bi Ing Chang
Publikováno v:
Cardiovascular Research. 105:107-117
Aims The recombinant epidermal growth factor-like domain plus the serine/threonine-rich domain of thrombomodulin (rTMD23) promotes angiogenesis and accelerates the generation of activated protein C (APC), which facilitates angiogenesis. The aim of th
Autor:
Tsung Lin Cheng, Cheng Hsiang Kuo, Yi Kai Hong, Guey Yueh Shi, Yun Yan Hsu, Hua Lin Wu, Chao Kai Hsu, Jui Ting Li, Kuan Chieh Wang, Chih Yuan Ma, Yao Chou Lee, Chao Han Lai, Bi Ing Chang, Shu-Wha Lin
Publikováno v:
Journal of Investigative Dermatology. 139:2204-2214.e7
Tumor endothelial marker 1 (TEM1), also known as endosialin or CD248, is a type I transmembrane glycoprotein containing a C-type lectin-like domain. It is highly expressed in pericytes and fibroblasts. Dermal fibroblasts play a pivotal role during cu
Autor:
Tsung Lin Cheng, Chih Yuan Ma, Hua Lin Wu, Yu Jen Yang, Cheng Hsiang Kuo, Chao Han Lai, Bi Ing Chang, Fu Chih Hsu, Fang Tzu Lee, Guey Yueh Shi
Publikováno v:
Annals of Surgery. 258:1103-1110
To investigate whether recombinant thrombomodulin containing all the extracellular domains (rTMD123) has therapeutic potential against aneurysm development.The pathogenesis of abdominal aortic aneurysm (AAA) is characterized by chronic inflammation a