Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bhuvaneshwari D/O Shunmuganathan"'
Autor:
Nikhil Kumar Tulsian, Raghuvamsi Venkata Palur, Xinlei Qian, Yue Gu, Bhuvaneshwari D/O Shunmuganathan, Firdaus Samsudin, Yee Hwa Wong, Jianqing Lin, Kiren Purushotorman, Mary McQueen Kozma, Bei Wang, Julien Lescar, Cheng-I Wang, Ravindra Kumar Gupta, Peter John Bond, Paul Anthony MacAry
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract The changing landscape of SARS-CoV-2 Spike protein is linked to the emergence of variants, immune-escape and reduced efficacy of the existing repertoire of anti-viral antibodies. The functional activity of neutralizing antibodies is linked t
Externí odkaz:
https://doaj.org/article/54f52c1fa0c948c5b812e8554189a002
Autor:
Saket Jhajharia, Fritz Lai, Heng Boon Low, Kiren Purushotorman, Bhuvaneshwari D/O Shunmuganathan, Conrad En Zuo Chan, Rachel Hammond, Hans-Jürgen Netter, Qingfeng Chen, Seng Gee Lim, Paul A. MacAry
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Hepatitis B Virus (HBV) is a hepadnavirus that is the principal pathogen underlying viral liver disease in human populations. In this study, we describe the isolation and characterization of a fully human monoclonal antibody for HBV. This Hu
Externí odkaz:
https://doaj.org/article/fb283a36a7c34a808b9658dccca347d5
Autor:
Patthara Kongsuphol, Huan Jia, Hoi Lok Cheng, Yue Gu, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Sing Mei Lim, Say Yong Ng, Paul Ananth Tambyah, Haziq Nasir, Xiaohong Gao, Dousabel Tay, Seunghyeon Kim, Rashi Gupta, Xinlei Qian, Mary M. Kozma, Kiren Purushotorman, Megan E. McBee, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-12 (2021)
Kongsuphol et al. develop a paper-based, vertical flow assay to detect SARS-CoV-2 neutralizing antibodies. The point-of-care assay has comparable performance to lab-based tests and provides results in 10 min.
Externí odkaz:
https://doaj.org/article/663f8b27aead4a418e60988c13e46a00
Autor:
Jia Ming Low, Yue Gu, Melissa Shu Feng Ng, Zubair Amin, Le Ye Lee, Yvonne Peng Mei Ng, Bhuvaneshwari D/O Shunmuganathan, Yuxi Niu, Rashi Gupta, Paul Anantharajah Tambyah, Paul A. MacAry, Liang Wei Wang, Youjia Zhong
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-8 (2021)
Abstract Lactating women can produce protective antibodies in their milk after vaccination, which has informed antenatal vaccination programs for diseases such as influenza and pertussis. However, whether SARS-CoV-2-specific antibodies are produced i
Externí odkaz:
https://doaj.org/article/749b499ea3534b56a5678b0ba67e1df9
Autor:
Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P. Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Megan E. McBee, Barnaby E. Young, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract There is clinical need for a quantifiable point‐of‐care (PoC) SARS‐CoV‐2 neutralizing antibody (nAb) test that is adaptable with the pandemic's changing landscape. Here, we present a rapid and semi‐quantitative nAb test that uses f
Externí odkaz:
https://doaj.org/article/d63c818224ae4a54916797daab64c017
Autor:
Nikhil Tulsian, Palur Raghuvamsi, Xinlei Qian, Yue Gu, Bhuvaneshwari D/O Shunmuganathan, Firdaus Samsudin, Yee Hwa Wong, Jianqing Lin, Kiren Purushotorman, Mary Kozma, BEI WANG, Julien Lescar, Cheng-I Wang, Ravindra Gupta, Peter Bond, Paul MacAry
The changing landscape of mutations in the SARS-CoV-2 Spike protein is linked to the emergence of variants, immune-escape and reduced efficacy of the existing repertoire of anti-viral antibodies. A major factor that contributes to the functional acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd2e04aa582f3a355e27b325f33512af
https://doi.org/10.21203/rs.3.rs-2465199/v1
https://doi.org/10.21203/rs.3.rs-2465199/v1
Autor:
Yue Gu, Jia Ming Low, Jolene S.Y. Tan, Melissa Shu Feng Ng, Lisa F.P. Ng, Bhuvaneshwari D/O Shunmuganathan, Rashi Gupta, Paul A. MacAry, Zubair Amin, Le Ye Lee, Derrick W.Q. Lian, Lynette Pei-Chi Shek, Youjia Zhong, Liang Wei Wang
BackgroundCOVID-19 has been a major public health threat for the past two years, with disproportionate effects on the elderly, immunocompromised, and pregnant women. While much has been done in delineating immune dysfunctions and pathogenesis in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::698f426b4c5d7dc49cd7ad3a0da307e7
https://doi.org/10.1101/2022.04.19.22273864
https://doi.org/10.1101/2022.04.19.22273864
Autor:
Nikhil K. Tulsian, Palur V. Raghuvamsi, Xinlei Qian, Gu Yue, Bhuvaneshwari D/O Shunmuganathan, Firdaus Samsudin, Wong Yee Hwa, Lin Jianqing, Kiren Purushotorman, Mary M. Kozma, Bei Wang, Julien Lescar, Cheng-I Wang, Ganesh S. Anand, Peter J. Bond, Paul A. MacAry
Previous studies on the structural relationship between human antibodies and SARS-CoV-2 have focused on generating static snapshots of antibody complexes with the Spike trimer. However, antibody-antigen interactions are dynamic, with significant bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5f52b056b592f4e77e5529cd1f6e3f8
https://doi.org/10.1101/2021.12.27.474251
https://doi.org/10.1101/2021.12.27.474251
Autor:
Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P. Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Megan E. McBee, Barnaby E. Young, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Bioengineeringtranslational medicine. 7(2)
There is clinical need for a quantifiable point-of-care (PoC) SARS-CoV-2 neutralizing antibody (nAb) test that is adaptable with the pandemic's changing landscape. Here, we present a rapid and semi-quantitative nAb test that uses finger stick or veno