Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bhushan N. Dave"'
Autor:
Krishnarup Ghoshdastidar, Jeevan Kumar, Jogeswar Mahapatra, Ranjit C. Desai, Dipam Patel, Debdutta Bandyopadhyay, S. Sachchidanand, Purvi Vyas, Rajesh Bahekar, Radhika Funde, Abhijit Chatterjee, Poonam Giri, Shubhangi S. Soman, Bhushan N. Dave, Rajendra Chopade
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:1313-1319
PI3Kδ is implicated in various inflammatory and autoimmune diseases. For the effective treatment of chronic immunological disorders such as rheumatoid arthritis, it is essential to develop isoform selective PI3Kδ inhibitors. Structure guided optimi
Autor:
Dipam Patel, Ranjit C. Desai, Darshan A. Joshi, Amitgiri D. Goswami, Sameer Agarwal, Jignesh P. Pethani, Pradip Jadav, Rajesh Bahekar, Hardik A. Shah, Bhushan N. Dave
Publikováno v:
Organic Process Research & Development. 21:266-272
Hexahydrocyclopentapyrrolone derivatives constitute an important class of bicycles, and it represents an essential pharmacophore for diversified pharmacological activities. A highly efficient process for the synthesis of tert-butyl(3aR,6aS)-5-oxohexa