Role of cardiopulmonary interactions in development of ventilator-induced lung injury—Experimental evidence and clinical Implications

Autor: Neel Shah, Bhushan H. Katira

Publikováno v: Frontiers in Physiology, Vol 14 (2023)

Ventilator-induced lung injury (VILI) impacts outcomes in ARDS and optimization of ventilatory strategies improves survival. Decades of research has identified various mechanisms of VILI, largely focusing on airspace forces of plateau pressure, tidal

Externí odkaz: https://doaj.org/article/100b32b123d145d4be6bb2e9164a1108

Mechanical Ventilation in ARDS With an Automatic Resuscitator

Autor: Mayson L A, Sousa, Bhushan H, Katira, Doreen, Engelberts, Vanessa, Hsing, Annia, Schreiber, Annemijn H, Jonkman, Martin, Post, Paul, Dorian, Laurent J, Brochard

Publikováno v: Sousa, M L A, Katira, B H, Engelberts, D, Hsing, V, Schreiber, A, Jonkman, A H, Post, M, Dorian, P & Brochard, L J 2023, ' Mechanical Ventilation in ARDS With an Automatic Resuscitator ', Respiratory care, vol. 68, no. 5, pp. 611-619 . https://doi.org/10.4187/respcare.10389
Respiratory care, 68(5), 611-619. Daedalus Enterprises Inc.

BACKGROUND: The Oxylator is an automatic resuscitator, powered only by an oxygen cylinder with no electricity required, that could be used in acute respiratory failure in situations in which standard mechanical ventilation is not available or feasibl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed7ecc178d26524a283990a2879c6a0
https://research.vumc.nl/en/publications/90a386b8-0518-498a-a21b-d8262e7b2966

Understanding clinical and biological heterogeneity to advance precision medicine in paediatric acute respiratory distress syndrome

Autor: Martin C J Kneyber, Robinder G Khemani, Anoopindar Bhalla, Robert G T Blokpoel, Pablo Cruces, Mary K Dahmer, Guillaume Emeriaud, Jocelyn Grunwell, Stavroula Ilia, Bhushan H Katira, Yolanda M Lopez-Fernandez, Prakadeshwari Rajapreyar, L Nelson Sanchez-Pinto, Peter C Rimensberger

Publikováno v: The Lancet. Respiratory medicine.

Paediatric acute respiratory distress syndrome (PARDS) is a heterogeneous clinical syndrome that is associated with high rates of mortality and long-term morbidity. Factors that distinguish PARDS from adult acute respiratory distress syndrome (ARDS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc7653a78810f8beda03a5f8943de59
https://pubmed.ncbi.nlm.nih.gov/36566767

Role of Positive End-Expiratory Pressure and Regional Transpulmonary Pressure in Asymmetrical Lung Injury

Autor: Lu Chen, Marcelo B. P. Amato, Martin Post, Brian P. Kavanagh, Bhushan H. Katira, Doreen Engelberts, Niall D. Ferguson, L. Bastia, L. Felipe Damiani, Takeshi Yoshida, Laurent Brochard, K. Osada

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 203:969-976

Rationale: Asymmetrical lung injury is a frequent clinical presentation. Regional distribution of Vt and positive end-expiratory pressure (PEEP) could result in hyperinflation of the less-injured l...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4943200e689bcca0b8f29a7a6f963035
https://doi.org/10.1164/rccm.202005-1556oc

Impact of Reverse Triggering Dyssynchrony during Lung-Protective Ventilation on Diaphragm Function: An Experimental Model

Autor: L. Felipe Damiani, Doreen Engelberts, Luca Bastia, Kohei Osada, Bhushan H. Katira, Gail Otulakowski, Ewan C. Goligher, W. Darlene Reid, Sebastián Dubo, Alejandro Bruhn, Martin Post, Brian P. Kavanagh, Laurent J. Brochard

Publikováno v: American journal of respiratory and critical care medicine. 205(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cf55f09f5c9d75f72ae4bda587f10b
https://pubmed.ncbi.nlm.nih.gov/35139008