Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bhupinder P.S. Vohra"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Axon degeneration is a prominent feature of various neurodegenerative diseases, such as Parkinson’s and Alzheimer’s, and is often characterized by aberrant mitochondrial dynamics. Mitochondrial fission, fusion, and motility have been shown to be
Externí odkaz:
https://doaj.org/article/0a387cdceab946f1868f8f117d6de193
Autor:
Bhupinder P.S. Vohra, Jason S. Groshong, Roberto Zayas, Robert L. Wollmann, Christopher M. Gomez
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 2, Pp 462-470 (2006)
In the slow-channel syndrome (SCS) mutant acetylcholine receptors elicit calcium overload and myonuclear degeneration at the neuromuscular junction (NMJ), without muscle fiber death. Activated caspases are present at SCS motor endplates. We hypothesi
Externí odkaz:
https://doaj.org/article/15d370629a8b4762bd00c087599455cd
Publikováno v:
Molecular and Cellular Neuroscience. 125:103853
Autor:
Bhupinder P.S. Vohra, Paul D. Klawinski, Jesse Rose, Clayton Mansel, Emily Dema, Shaneann Fross, Haley Hart, Alexis Mann
Publikováno v:
Neurotoxicology and Teratology. 72:58-70
Lead (Pb) is a teratogen that poses health risks after acute and chronic exposure. Lead is deposited in the bones of adults and is continuously leached into the blood for decades. While this chronic lead exposure can have detrimental effects on adult
Publikováno v:
Neurochemistry International. 121:86-97
Golgi fragmentation and loss of Nicotinamide Mononucleotide Adenylyltransferase 2 (NMNAT2) are the early key features of many neurodegenerative disorders. We investigated the link between NMNAT2 loss, Golgi fragmentation and axon degeneration. Golgi
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 180(2)
Tributyltin (TBT) remains a global health concern. The primary route of human exposure to TBT is either through ingestion or skin absorption, but TBT’s effects on the peripheral nervous system have still not been investigated. Therefore, we exposed
Publikováno v:
Neurochemical Research. 43:2288-2303
Gut motility malfunction and pathological changes in the enteric nervous system (ENS) are observed in the early stages of Parkinson's disease (PD). In many cases disturbances in the autonomous functions such as gut motility precedes the observed loss
Publikováno v:
Journal of Biological Chemistry. 286:28011-28018
Axon degeneration is an active, evolutionarily conserved self-destruction program by which compromised axons fragment in response to varied insults. Unlike programmed cell death, axon degeneration is poorly understood. We have combined robotic liquid
Publikováno v:
Neurochemistry international. 63(8)
Depending upon the stimulus, neuronal cell death can either be triggered from the cell body (soma) or the axon. We investigated the origin of the degeneration signal in amyloid β (Aβ) induced neuronal cell death in cultured in vitro hippocampal neu
Autor:
Bhupinder P.S. Vohra, William Planer, Jennifer Armon, Ming Fu, Sanjay Jain, Robert O. Heuckeroth
Publikováno v:
Developmental Dynamics; Jan2007, Vol. 236 Issue 1, p106-117, 12p