Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bhupesh K. Thakur"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1177-1197 (2021)
Inflammatory bowel disease (IBD) patients have an increased risk of developing colitis-associated colon cancer (CAC); however, the basis for inflammation-induced genetic damage requisite for neoplasia is unclear. Several studies have shown that IBD p
Externí odkaz:
https://doaj.org/article/df9372db18f54415b3dd1c0b95453e41
Autor:
Thergiory Irrazabal, Bhupesh K. Thakur, Mingsong Kang, Yann Malaise, Catherine Streutker, Erin O. Y. Wong, Julia Copeland, Robert Gryfe, David S. Guttman, William W. Navarre, Alberto Martin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
It is unclear how microbial-induced inflammation promotes neoplastic transformation in colitis-associated cancer (CAC). Here, the authors use models of CAC to show that inflammation induces 8-oxoguanine lesions in DNA, and that antioxidants can reduc
Externí odkaz:
https://doaj.org/article/526a67a99acf4d7686fe026f8f5cd7e5