Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Bhupendra N. Singh"'
Autor:
Mohd Mustkim Ansari, Sariyah Akhtar, Kalyan Mitra, Devesh Pratap Verma, Bhupendra N. Singh, Jimut Kanti Ghosh, Garima Pant, Neeraj Verma, Jyotshana Saroj
Publikováno v:
Journal of Medicinal Chemistry. 64:15349-15366
To design novel antimicrobial peptides by utilizing the sequence of the human host defense protein, chemerin, a seven-residue amphipathic stretch located in the amino acid region, 109-115, was identified, which possesses the highest density of hydrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2abc51587ae48c649c898a3a76f895e
https://doi.org/10.1021/acs.jmedchem.1c01352
https://doi.org/10.1021/acs.jmedchem.1c01352
Publikováno v:
SAR and QSAR in Environmental Research. 32:191-205
Acetyl Coenzyme A Carboxylase (AccD6) is a homodimeric protein which is involved in the carboxylation of acetyl coenzyme A to produce malonyl coenzyme A, which plays an important role in the biosyn...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac937a99692d239a7868b27e7b943dcc
https://doi.org/10.1080/1062936x.2021.1882563
https://doi.org/10.1080/1062936x.2021.1882563
Autor:
Sandeep K. Sharma, Pintu Das, Arun K. Shaw, Bhupendra N. Singh, Somireddy Kundooru, Ravikant Pandole
Publikováno v:
Tetrahedron: Asymmetry. 27:101-106
The C -alkylated biologically important pyrrolidine iminosugars have been synthesized from commercially available d -mannose. The key step of this strategy involves the diastereoselective Grignard addition to d -mannose derived nitrone 7 . These unna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::943c0f4e7203c7afd444d3fb88a95dd0
https://doi.org/10.1016/j.tetasy.2015.12.003
https://doi.org/10.1016/j.tetasy.2015.12.003
Autor:
Jitendra Kuldeep, Mohammad Imran Siddiqi, Bhupendra N. Singh, Sandeep K. Sharma, Tanuj Sharma
Publikováno v:
Molecular Informatics. 40:2000211
Enoyl-acyl carrier protein reductase (InhA) of type II fatty acid synthase system is involved in the synthesis of mycolic acids which is a major component of the bacterial cell wall. Since they are the key enzymes playing a very significant role in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef2d9bfe8d71b62b585f5b4b71bb40a
https://doi.org/10.1002/minf.202000211
https://doi.org/10.1002/minf.202000211
Publikováno v:
Bioorganic Chemistry. 99:103775
We have designed and synthesized 2-methoxy-3-(thiophen-2-ylmethyl)quinoline containing amino carbinols as possible anti-tubercular agents to combat the disease. These molecules were synthesized by tethering amino ether linkage with hydroxyl group to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d78d3f24116b0ee29f1359740756ca0
https://doi.org/10.1016/j.bioorg.2020.103775
https://doi.org/10.1016/j.bioorg.2020.103775
Autor:
Sushil K. Dwivedi, Anil Kumar Tripathi, Sudhir Singh, Ashutosh Kumar Rai, Santosh Kumar, Amit Srivastava, Parul Pandey, Bhupendra N. Singh
Publikováno v:
Applied and Environmental Microbiology. 84
The genome of Azospirillum brasilense encodes five RpoH sigma factors: two OxyR transcription regulators and three catalases. The aim of this study was to understand the role they play during oxidative stress and their regulatory interconnection. Out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64af97edc3c41746dc84eef2137c7e19
https://doi.org/10.1128/aem.01787-18
https://doi.org/10.1128/aem.01787-18
Autor:
Bhupendra N. Singh, Vishal Srivastava, Anirudh K. Singh, Rajesh Kumar Biswas, Debashis Dutta, Vandana Singh
Publikováno v:
MicrobiologyOpen. 4:896-916
In Mycobacterium smegmatis, sigF is widely expressed during different growth stages and plays role in adaptation to stationary phase and oxidative stress. Using a sigF deletion mutant of M. smegmatis mc(2) 155, we demonstrate that SigF is not essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309aa4cff81e590669ebb97c1f31aeea
https://doi.org/10.1002/mbo3.288
https://doi.org/10.1002/mbo3.288
Autor:
Dinesh K. Dikshit, Sudhir Sinha, Kuldeep K. Roy, Bhupendra N. Singh, K.S. Anil Kumar, Dimpy Kalia, Shyam Singh, Anil K. Saxena, Vinita Chaturvedi, Ruchir Kant, Shaheb Raj Khan, Manju Yasodha Krishnan, Sandeep K. Sharma, Rohit Sharma, Priyanka Trivedi, Kashmir Prasad Sethi, Gajanand Meena, Ajay Singh Verma
Publikováno v:
MedChemComm. 6:1554-1563
One of the most significant breakthroughs in the battle against tuberculosis is the recent approval of the quinoline compound, TMC207, for the treatment of drug-resistant tuberculosis. To gain insight into the molecular determinants of the activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fc8d6c34e5c57edf3bf347ed64dea62
https://doi.org/10.1039/c5md00131e
https://doi.org/10.1039/c5md00131e
Autor:
Abhishek Arya, Sanjeev Kanojiya, Manish K. Chourasia, Anil K. Saxena, Pankaj Dwivedi, Bhupendra N. Singh, Shakti Deep Pachauri, Kiran Khandelwal, Anil Kumar Dwivedi, Komal Sharma, Vivek K. Pawar, Hafsa Ahmad, Trapti Joshi
Publikováno v:
RSC Advances. 5:39168-39176
S002-333, a novel anti-thrombotic agent, exhibits excellent platelet mediated antithrombotic action and subsequently has no effect on the coagulation cascade. However, its oral bioavailability is hampered due to inherent low aqueous solubility. In or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9103d2010793be7556a63b23a6ea150a
https://doi.org/10.1039/c5ra01543j
https://doi.org/10.1039/c5ra01543j