Targeting ketone body metabolism in mitigating gemcitabine resistance.

Autor: Rohena-Rivera K; Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, United States of America., You S; Department of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, United States of America., Kim M; Department of Urology, Cedars-Sinai Medical Center, Los Angeles, United States of America., Billet S; Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, United States of America., Ten Hoeve J; UCLA Metabolomics Center, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, United States of America., Gonzales G; Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, United States of America., Huang C; Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, United States of America., Heard A; Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, United States of America., Chan KS; Department of Urology and Neal Cancer Center, Houston Methodist Research Institute, Houston, United States of America., Bhowmick NA; Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, United States of America.

Publikováno v: JCI insight [JCI Insight] 2024 Nov 07. Date of Electronic Publication: 2024 Nov 07.

Glutamine Supplementation as an Anticancer Strategy: A Potential Therapeutic Alternative to the Convention.

Autor: Muranaka H; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Akinsola R; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Billet S; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Pandol SJ; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Hendifar AE; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Bhowmick NA; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Research, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA., Gong J; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Publikováno v: Cancers [Cancers (Basel)] 2024 Mar 05; Vol. 16 (5). Date of Electronic Publication: 2024 Mar 05.

Clinical Utility of Olaparib in the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Review of Current Evidence and Patient Selection

Autor: LeVee A, Lin CY, Posadas E, Figlin R, Bhowmick NA, Di Vizio D, Ellis L, Rosser CJ, Freeman MR, Theodorescu D, Freedland SJ, Gong J

Publikováno v: OncoTargets and Therapy, Vol Volume 14, Pp 4819-4832 (2021)

Alexis LeVee,1 Ching Ying Lin,1 Edwin Posadas,1 Robert Figlin,1 Neil A Bhowmick,1 Dolores Di Vizio,2 Leigh Ellis,1 Charlos J Rosser,3 Michael R Freeman,2 Dan Theodorescu,2 Stephen J Freedland,3,4 Jun Gong1 1Department of Medicine, Division of Hematol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::0cad9a0636987be6e84293522a08a033
https://www.dovepress.com/clinical-utility-of-olaparib-in-the-treatment-of-metastatic-castration-peer-reviewed-fulltext-article-OTT

Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment.

Autor: Wang Z; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China., Kim SY; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Tu W; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Division of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 China., Kim J; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Xu A; Division of Hematology and Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Yang YM; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Pharmacy, Kangwon National University, Chuncheon 24341, South Korea., Matsuda M; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Reolizo L; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Tsuchiya T; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Billet S; Division of Hematology and Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Gangi A; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Noureddin M; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Houston Methodist Hospital, Houston Research Institute, Houston, TX 77030, USA., Falk BA; Division of Hematology and Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Kim S; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Fan W; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Tighiouart M; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., You S; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Lewis MS; Division of Hematology and Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Pathology, Veterans Affairs Greater Los Angeles Health Care System, Los Angeles, CA 90073, USA., Pandol SJ; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Di Vizio D; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Merchant A; Division of Hematology and Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Posadas EM; Division of Hematology and Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Bhowmick NA; Division of Hematology and Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Lu SC; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Seki E; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address: ekihiro.seki@cshs.org.

Publikováno v: Cell metabolism [Cell Metab] 2023 Jul 11; Vol. 35 (7), pp. 1209-1226.e13. Date of Electronic Publication: 2023 May 11.

Corrigendum to "Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism" [Mitochondrion 71 (2023) 40-49].

Autor: Borah S; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles 90048, CA, USA., Mishra R; Department of Life Sciences, CSJM University, Kanpur, Uttar Pradesh 208012, India., Dey S; Department of Physiology, University of Gour Banga, Malda 732103, India., Suchanti S; Department of Biosciences, Manipal University Jaipur, Rajasthan 303007, India., Bhowmick NA; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles 90048, CA, USA; Department of Research, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA., Giri B; Department of Physiology, University of Gour Banga, Malda 732103, India. Electronic address: bgiri.emscrl@gmail.com., Haldar S; Department of Biochemistry, Bose Institute, Kolkata 700091, India. Electronic address: subhash.haldar@jcbose.ac.in.

Publikováno v: Mitochondrion [Mitochondrion] 2023 Jul; Vol. 71, pp. 63. Date of Electronic Publication: 2023 Jun 03.