Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bhoomika Sherkhane"'
Autor:
Chayanika Gundu, Vijay Kumar Arruri, Bhoomika Sherkhane, Dharmendra Kumar Khatri, Shashi Bala Singh
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 3, Iss , Pp 100087- (2022)
Neuronal dysfunction and subsequent apoptosis under high glucose conditions during diabetes contribute majorly to the manifestation of diabetic peripheral neuropathy (DPN). PERK (protein kinase RNA (PKR)-like ER kinase) one among the three canonical
Externí odkaz:
https://doaj.org/article/25083657042d4500a2005f08a2f27fe0
Autor:
Jain Siddhi, Bhoomika Sherkhane, Anil Kumar Kalavala, Vijay Arruri, Ravichandiran Velayutham, Ashutosh Kumar
Publikováno v:
Cell biology internationalREFERENCES. 46(12)
Impaired nutrient sensing mechanisms such as AMPK/silent information regulator type 1 (SIRT1) axis and autophagy in renal cells upon chronic diabetic condition accelerate renal injury and upregulating these mechanisms has been reported to prevent ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a5c53a8b914873d5aebf4b52febbe7
https://pubmed.ncbi.nlm.nih.gov/36086947
https://pubmed.ncbi.nlm.nih.gov/36086947
Autor:
Chayanika Gundu, Shashi Bala Singh, Anil Kumar Kalvala, Dharmendra Kumar Khatri, Bhoomika Sherkhane, Vijay Kumar Arruri
Publikováno v:
Nutritional Neuroscience. 25:1731-1746
Objectives: We aimed to evaluate the effect of carvacrol (CRC), a phenolic monoterpene with high nutritional value on NLRP3 activation against chronic constriction injury (CCI) of sciatic nerve induced neuropathic pain (NP) in rats and in lipopolysac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02c453b2cb2af82f57e4bd8afc62859
https://doi.org/10.1080/1028415x.2021.1892985
https://doi.org/10.1080/1028415x.2021.1892985
Autor:
Chayanika Gundu, Vijay Kumar Arruri, Bhoomika Sherkhane, Dharmendra Kumar Khatri, Shashi Bala Singh
Publikováno v:
Archives of physiology and biochemistry.
We aimed to evaluate the neuroprotective effect of Indole-3-propionic acid (IPA) against streptozotocin (STZ) induced diabetic peripheral neuropathy (DPN) in rats and in high glucose (HG) induced neurotoxicity in neuro2a (N2A) cells.Diabetes was indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dfee4e6027bc58b5df4cfb5566be13
https://pubmed.ncbi.nlm.nih.gov/35015592
https://pubmed.ncbi.nlm.nih.gov/35015592
Publikováno v:
Molecular Biology Reports.
Diabetes mellitus (DM) is a chronic, metabolic condition characterized by excessive blood glucose that causes perturbations in physiological functioning of almost all the organs of human body. This devastating metabolic disease has its implications i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989b8c15e9bde59ec258fa03c9866f87
https://doi.org/10.1007/s11033-021-06408-8
https://doi.org/10.1007/s11033-021-06408-8
Autor:
Bhoomika, Sherkhane, Gundu, Chayanika, Anika, Sood, Dharmendra Kumar, Khatri, Shashi Bala, Singh
Publikováno v:
Molecular biology reports. 48(5)
Diabetes mellitus (DM) is a chronic, metabolic condition characterized by excessive blood glucose that causes perturbations in physiological functioning of almost all the organs of human body. This devastating metabolic disease has its implications i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::369f7c1c6fc0d8ce05fbe6966b2e1dc5
https://pubmed.ncbi.nlm.nih.gov/34023988
https://pubmed.ncbi.nlm.nih.gov/34023988
Autor:
Bhoomika Sherkhane, Ashutosh Kumar, Rajesh Kumar, Anil Kumar Kalvala, Vijay Kumar Arruri, Chayanika Gundu
Publikováno v:
Molecular neurobiology. 57(8)
Bardoxolone methyl (Bard), a nuclear factor erythroid 2-related factor 2 (Nrf2) activator regulates multiple oxidative and inflammatory diseases. However, the role of Bard in painful diabetic neuropathy (DN) remains unknown. Bard administration at tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9610b58fbccc36f38714d04c7494e940
https://pubmed.ncbi.nlm.nih.gov/32556916
https://pubmed.ncbi.nlm.nih.gov/32556916
Autor:
Chayanika Gundu, Bhoomika Sherkhane, Anil Kumar Kalvala, Ashutosh Kumar, Veera Ganesh Yerra, Rajesh Kumar, Vijay Kumar Arruri
Publikováno v:
Pharmacological reports : PR. 72(6)
Disturbed mitochondrial homeostasis has been identified to contribute to the pathogenesis of diabetic neuropathy (DN). However, the role of Mitochondrial Lon peptidase 1 (Lonp1) and Heat shock proteins (HSP’s) in DN remains elusive. Here we studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b65dbb773e2303942066b7cf3aab7fa
https://pubmed.ncbi.nlm.nih.gov/32720218
https://pubmed.ncbi.nlm.nih.gov/32720218
Autor:
Anil Kumar Kalvala, Ashutosh Kumar, Bhoomika Sherkhane, Veera Ganesh Yerra, Preethi Bheereddy
Publikováno v:
Cellular and molecular neurobiology. 41(7)
Mitochondrial dysfunction has been implicated as a one of the major factors linked to the development of painful diabetic neuropathy (DN). Several studies have demonstrated that sirtuin (SIRT1) activation recuperates nerve function by activating mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8d3d8e3f4b7496afa0ccffd53a913b
https://pubmed.ncbi.nlm.nih.gov/32683581
https://pubmed.ncbi.nlm.nih.gov/32683581
Publikováno v:
Neuropharmacology. 131
Adenosine monophosphate-activated protein kinase (AMPK) has been studied for its myriad metabolic and mitochondrial benefits in several chronic diseases. Recent studies have uncovered its therapeutic potential against mitochondrial dysfunction in cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f283ebf6e426951baa10dbebd1cc01f
https://pubmed.ncbi.nlm.nih.gov/29273519
https://pubmed.ncbi.nlm.nih.gov/29273519