Microdomain-Specific Modulation of L-type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure

Autor: Sanchez-Alonso, JL, Bhargava, A, O'Hara, T, Glukhov, AV, Schobesberger, S, Bhogal, NK, Sikkel, MB, Mansfield, C, Korchev, YE, Lyon, AR, Punjabi, PP, Nikolaev, VO, Trayanova, NA, Gorelik, J

RATIONALE: Disruption in subcellular targeting of Ca(2+) signaling complexes secondary to changes in cardiac myocyte structure may contribute to the pathophysiology of a variety of cardiac diseases, including heart failure (HF) and certain arrhythmia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::79023285641cafed990e2c47cceca531
http://hdl.handle.net/10044/1/39657

Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β 2 AR-cAMP Responsiveness in Murine Hearts.

Autor: Wright PT; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK., Bhogal NK; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK., Diakonov I; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK., Pannell LMK; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK., Perera RK; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Bork NI; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Schobesberger S; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Lucarelli C; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; Department of Cardiac Surgery, University of Verona School of Medicine, Azienda Ospedalieria Universitaria Integrata, Borgo Trento Piazzale A. Stefani, 37126 Verona, Italy., Faggian G; Department of Cardiac Surgery, University of Verona School of Medicine, Azienda Ospedalieria Universitaria Integrata, Borgo Trento Piazzale A. Stefani, 37126 Verona, Italy., Alvarez-Laviada A; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK., Zaccolo M; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK., Kamp TJ; Department of Medicine, University of Wisconsin Madison, 1111 Highland Ave., Madison, WI 53705-2275, USA., Balijepalli RC; Department of Medicine, University of Wisconsin Madison, 1111 Highland Ave., Madison, WI 53705-2275, USA., Lyon AR; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London SW7 3AZ, UK., Harding SE; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK., Nikolaev VO; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Gorelik J; Myocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK. Electronic address: j.gorelik@imperial.ac.uk.

Publikováno v: Cell reports [Cell Rep] 2018 Apr 10; Vol. 23 (2), pp. 459-469.

Perioperative management of Takotsubo cardiomyopathy: an overview.

Autor: Pillitteri, Marta, Brogi, Etrusca, Piagnani, Chiara, Bozzetti, Giuseppe, Forfori, Francesco

Publikováno v: Journal of Anesthesia, Analgesia & Critical Care; 7/15/2024, Vol. 4 Issue 1, p1-15, 15p

Pathophysiology of Takotsubo syndrome – a joint scientific statement from the Heart Failure Association Takotsubo Syndrome Study Group and Myocardial Function Working Group of the European Society of Cardiology – Part 1: overview and the central role for catecholamines and sympathetic nervous system

Autor: Omerovic, Elmir¹ (AUTHOR) elmir@wlab.gu.se, Citro, Rodolfo² (AUTHOR), Bossone, Eduardo³ (AUTHOR), Redfors, Bjorn¹ (AUTHOR), Backs, Johannes^4,5 (AUTHOR), Bruns, Bastian^4,5,6 (AUTHOR), Ciccarelli, Michele⁷ (AUTHOR), Couch, Liam S.⁸ (AUTHOR), Dawson, Dana⁹ (AUTHOR), Grassi, Guido¹⁰ (AUTHOR), Iacoviello, Massimo¹¹ (AUTHOR), Parodi, Guido¹² (AUTHOR), Schneider, Birke¹³ (AUTHOR), Templin, Christian¹⁴ (AUTHOR), Ghadri, Jelena R.¹⁴ (AUTHOR), Thum, Thomas¹⁵ (AUTHOR), Chioncel, Ovidiu¹⁶ (AUTHOR), Tocchetti, C. Gabriele¹⁷ (AUTHOR), van der Velden, Jolanda¹⁸ (AUTHOR), Heymans, Stephane^19,20 (AUTHOR)

Publikováno v: European Journal of Heart Failure. Feb2022, Vol. 24 Issue 2, p257-273. 17p. 1 Color Photograph, 3 Charts, 3 Graphs.

Role of autonomic nervous system in BDE-209 maternal exposure induced immunotoxicity in female offspring.

Autor: Mao G; School of the Emergency Management, Jiangsu University, Zhenjiang, China.; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Tang J; School of the Emergency Management, Jiangsu University, Zhenjiang, China.; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Xu M; School of the Emergency Management, Jiangsu University, Zhenjiang, China.; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Okeke ES; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China.; Department of Biochemistry, Faculty of Biological Sciences & Natural Science Unit, School of General Studies, University of Nigeria, Enugu, Nigeria., Dong F; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Chen Y; School of the Emergency Management, Jiangsu University, Zhenjiang, China.; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Gao J; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Feng W; School of the Emergency Management, Jiangsu University, Zhenjiang, China.; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Zhao T; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China., Wu X; School of the Emergency Management, Jiangsu University, Zhenjiang, China.; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China., Yang L; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China.

Publikováno v: Environmental toxicology [Environ Toxicol] 2024 Sep; Vol. 39 (9), pp. 4397-4416. Date of Electronic Publication: 2024 May 29.