Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Bhlhe40"'
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Nuclear-enriched abundant transcript 1 (NEAT1), a long noncoding RNA (lncRNA), has been implicated in the colorectal cancer (CRC) progression. However, its upstream mechanism has not been well studied. In the present study, the fu
Externí odkaz:
https://doaj.org/article/c4b267643af3463b8aff9de76e2af49d
Publikováno v:
Patologìâ, Vol 21, Iss 1, Pp 23-27 (2024)
In modern medical science great attention is paid to the clarification of the molecular mechanisms, which are the basis of adaptation to environmental factors of unusual origin and/or extraordinary strength. The aim of the study is to determine th
Externí odkaz:
https://doaj.org/article/1344080d03214266b804dfd84a333858
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Vitamin A and retinoic acid (RA, a metabolite of vitamin A), are inextricably involved to the development of skeletal muscle in animals. However, the mechanisms regulating skeletal muscle development by vitamin A remain poorly rep
Externí odkaz:
https://doaj.org/article/69b1f27deb3d42fe9abe5bc7e2e4c034
Bhlhe40 deficiency attenuates LPS-induced acute lung injury through preventing macrophage pyroptosis
Autor:
Xingxing Hu, Menglin Zou, Weishuai Zheng, Minghui Zhu, Qinhui Hou, Han Gao, Xin Zhang, Yuan Liu, Zhenshun Cheng
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) as common life-threatening lung diseases with high mortality rates are mostly associated with acute and severe inflammation in lungs. Rec
Externí odkaz:
https://doaj.org/article/f586f7bb603f446ba607e97c49c4d083
Autor:
Yizhi Cao, Xuelong Wang, Yang Liu, Pengyi Liu, Jiejie Qin, Youwei Zhu, Shuyu Zhai, Yongsheng Jiang, Yihao Liu, Lijie Han, Jiaxin Luo, Ronghao Zhang, Minmin Shi, Liwen Wang, Xiaomei Tang, Meilin Xue, Jia Liu, Weishen Wang, Chenlei Wen, Xiaxing Deng, Chenghong Peng, Hao Chen, Dongfeng Cheng, Lingxi Jiang, Baiyong Shen
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Pancreatic cancer (PCa) is one of the most fatal human malignancies. The enhanced infiltration of stromal tissue into the PCa tumor microenvironment limits the identification of key tumor‐specific transcription factors and epigenomic abnor
Externí odkaz:
https://doaj.org/article/6df9a584624746ff8b1a120d7f95f5e7
Akademický článek
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Autor:
Bárbara Acosta-Iborra, Ana Isabel Gil-Acero, Marta Sanz-Gómez, Yosra Berrouayel, Laura Puente-Santamaría, Maria Alieva, Luis del Peso, Benilde Jiménez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7669 (2024)
Knowledge of the molecular mechanisms that underlie the regulation of major adaptive responses to an unbalanced oxygen tension is central to understanding tissue homeostasis and disease. Hypoxia-inducible transcription factors (HIFs) coordinate chang
Externí odkaz:
https://doaj.org/article/b1cdc4ee54224204a50efcda67cf1cbd
Autor:
Matthew J. Butcher, Rama Krishna Gurram, Xiaoliang Zhu, Xi Chen, Gangqing Hu, Vanja Lazarevic, Keji Zhao, Jinfang Zhu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
T-bet-expressing Th17 (T-bet+RORγt+) cells are associated with the induction of pathology during experimental autoimmune encephalomyelitis (EAE) and the encephalitic nature of these Th17 cells can be explained by their ability to produce GM-CSF. How
Externí odkaz:
https://doaj.org/article/8cd88d59ed244387b8829fc53ebf8205
Autor:
Chao Liu, Jiang Du, Jianwei Zheng, Ruizhe Zhang, Jialin Zhu, Bofan Xing, Lin Dong, Qianqian Zhou, Xiaofeng Yao, Song Gao, Yu Wang, Yu Ren, Xuan Zhou
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is the leading cause of cancer-related mortality, primarily due to the abundance of cancer-associated fibroblasts (CAFs), depleted effector T cells, and increased tumor cell stemness; hence, there is an urgent
Externí odkaz:
https://doaj.org/article/7dd6cd81d6fb4c88b06fc3bb463e45a5
Autor:
Yufeng Zhang, Min Yang, Sheng Zhang, Zhiqiang Yang, Yufan Zhu, Yi Wang, Zhe Chen, Xuan Lv, Zan Huang, Yuanlong Xie, Lin Cai
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Background Dysregulated osteoclast activity due to altered osteoclast differentiation causes multiple bone diseases. Osteoclasts are multinucleated giant cells derived from hematopoietic stem cells and play a major role in bone absorption. H
Externí odkaz:
https://doaj.org/article/8f0abeefd45c4a4289c8cfd68578ed21