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of 20
pro vyhledávání: '"Bhavna Tanna"'
Autor:
ALAN J WILLIAMS, BHAVNA TANNA
Publikováno v:
Biological Research, Vol 37, Iss 4, Pp 527-538 (2004)
Ryanodine binds with high affinity and specificity to a class of Ca2+-release channels known as ryanodine receptors (RyR). The interaction with RyR results in a dramatic alteration in function with open probability (Po) increasing markedly and rates
Externí odkaz:
https://doaj.org/article/64517df1c12140508c597c112f50e7ee
Autor:
Yan Lu, Aaron W. Gehr, Ifedioranma Anikpo, Rachel J. Meadows, Kevin J. Craten, Rim Bannout, Kalyani Narra, Anuradha Lingam, Bhavna Tanna, Bassam Ghabach, Rohit P. Ojha
Publikováno v:
Cancer Research. 82:P5-14
Background Current knowledge of cardiotoxicity risk after breast cancer treatment with anthracyclines or trastuzumab is largely derived from cohorts that under-represent socioeconomically disadvantaged patients. Cardiotoxicity risk among socioeconomi
Autor:
Yan Lu, Aaron W. Gehr, Ifedioranma Anikpo, Rachel J. Meadows, Kevin J. Craten, Kalyani Narra, Anuradha Lingam, Sandeep Kamath, Bhavna Tanna, Bassam Ghabach, Rohit P. Ojha
Publikováno v:
Breast cancer research and treatment. 195(3)
Purpose Evidence of cardiotoxicity risk related to anthracycline or trastuzumab exposure is largely derived from breast cancer cohorts that under-represent socioeconomically marginalized women, who may be at increased risk of cardiotoxicity because o
Autor:
Bhavna Tanna, Aaron W. Gehr, Tara M. Brinkman, Kalyani Narra, Yan Lu, Margaret M. Lubas, Bassam Ghabach, Rohit P. Ojha
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Limited information is available about the representativeness of survivors engaging in patient-centered research, despite the potential for threats to generalizability. We thus aimed to assess the representativeness of survivors engaged o
Autor:
Bhavna Tanna, Rohit P. Ojha, Yan Lu, Aaron W. Gehr, Bradford E. Jackson, Deanna Cross, Latha Neerukonda, Bassam Ghabach
Publikováno v:
Preventive medicine. 126
The Patient Protection and Affordable Care Act (ACA) has increased insurance coverage among underserved individuals, but the effect of ACA on cancer diagnosis is currently debated, particularly in Medicaid non-expansion states. Therefore, we aimed to
Autor:
Bassam Ghabach, Rohit P. Ojha, Latha Neerukonda, Deanna Cross, Bhavna Tanna, Yan Lu, Bradford E. Jackson
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:B079-B079
Background: The Patient Protection and Affordable Care Act (ACA), particularly provisions enacted in 2014 including the health insurance exchange and Medicaid expansion, aimed to reduce the number of uninsured individuals in the United States. The AC
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:A095-A095
Background: Several cancer organizations have emphasized the need for etiologic and prognostic research targeting underserved populations. Most studies have operationalized the term underserved as uninsured or impoverished, but unknown is whether the
Publikováno v:
Journal of Clinical Oncology. 38:e19041-e19041
e19041 Background: Patient-reported outcomes (PROs) are extensively described for cancer patients with access to care, but little information is available about PROs for socioeconomically disadvantaged cancer patients with barriers to care. Therefore
Autor:
S.R. Wayne Chen, Alan J. Williams, William Welch, Bhavna Tanna-Topan, Ruiwu Wang, Fiona C. Mead-Savery
Publikováno v:
Biophysical Journal. 96:1374-1387
We have tested the hypothesis that a high density of negative charge at the luminal mouth of the RyR2 pore plays a pivotal role in the high cation conductance and limited selectivity observed in this channel by introducing into each monomer a double
Autor:
Luc Ruest, Ruiwu Wang, Bhavna Tanna, Kishani M. Ranatunga, S.R. Wayne Chen, William Welch, Tracy M. Moreno-King, Alan J. Williams
Publikováno v:
Molecular Pharmacology. 68:840-846
The specific, high-affinity interaction of the plant toxin ryanodine with its molecular target the ryanodine receptor channel (RyR) has been instrumental in RyR research. Alanine scanning of putative pore regions of mouse RyR2 has highlighted the ami