Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bhavinkumar B, Patel"'
Autor:
Alfred Knudson, Levy Kopelovich, James A. Crowell, Peggy Conrad, Eric A. Ross, Samuel Litwin, Tao Zhang, Bruce M. Boman, Alfonso Bellacosa, Harry S. Cooper, Renata A. Coudry, Steven H. Seeholzer, Xin-Ming Li, Bhavinkumar B. Patel, Anthony T. Yeung
Supplementary Data 1-13 from One-Hit Effects in Cancer: Altered Proteome of Morphologically Normal Colon Crypts in Familial Adenomatous Polyposis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8036fad90b6d98393b0d621841857a7b
https://doi.org/10.1158/0008-5472.22377081.v1
https://doi.org/10.1158/0008-5472.22377081.v1
Autor:
Derrick J. Swinton, John D. Leszyk, Randall W. Burt, Todd E. Fox, Anne Stanley, Phillip D. Kim, Anthony T. Yeung, Scott A. Shaffer, Kelly A. Jones, Christopher D. South, Philip R. Gafken, John M. Neveu, Bhavinkumar B. Patel, Steven G. Kelsen, Lisa A. Jones, David A. Jones, Levy Kopelovich, William S. Lane, Bruce A. Stanley, Michael J. Hall, Heather Hampel, Alan S. Braverman, Hon Chiu Eastwood Leung, Albert de la Chapelle
Publikováno v:
Journal of Proteome Research. 12:4351-4365
Plasma proteomic experiments performed rapidly and economically using several of the latest high-resolution mass spectrometers were compared. Four quantitative hyperfractionated plasma proteomics experiments were analyzed in replicates by two AB SCIE
Autor:
Alfred G. Knudson, Harry S. Cooper, Yin A. He, Anthony T. Yeung, Steven H. Seeholzer, Renata A. Coudry, James A. Crowell, David Cheng, Bruce M. Boman, Sharon Howard, Levy Kopelovich, Elena L. Blagoi, Alfonso Bellacosa, Dawn M. Riddle, Emmanuelle Nicolas, Bhavinkumar B. Patel, Xin-Ming Li, Maketa P. Dixon, Peggy Conrad
Publikováno v:
Oncotarget
Here we compared the proteomes of primary fibroblast cultures derived from morphologically normal colonic mucosa of familial adenomatous polyposis (FAP) patients with those obtained from unaffected controls. The expression signature of about 19% of t
Autor:
Eileen Ke, Anthony T. Yeung, James A. Crowell, and Alfred Knudson, Xin-Ming Li, Joan Xie, Harry Cooper, Alfonso Bellacosa, Peggy Conrad, Samuel Litwin, Mazell Tetruashvily, Bruce M. Boman, Yibai Chen, Yin A. He, Margie L. Clapper, C. Glenn Miller, Eric A. Ross, Maketa P. Dixon, Bhavinkumar B. Patel, Anam H. Chaudhry, Levy Kopelovich, Steven H. Seeholzer, Tao Zhang, Elena L. Blagoi
Publikováno v:
Journal of Proteome Research. 6:2232-2238
We seek alterations in protein patterns at the earliest possible step on the path to cancer, namely, in cells of the target tissue from normal persons versus the corresponding normally appearing cells from persons who are heterozygous for mutation in
Autor:
Xin-Ming, Li, Bhavinkumar B, Patel, Elena L, Blagoi, Maketa D, Patterson, Steven H, Seeholzer, Steven H, Seehozer, Tao, Zhang, Shirish, Damle, Zhenqiang, Gao, Bruce, Boman, Anthony T, Yeung
Publikováno v:
Journal of Proteome Research. 3:821-833
Normal human colon crypt protein extract was resolved by two-dimensional gel electrophoresis using pH 6-11 immobilized pH gradient strips in the first dimension. The optimized isoelectric focusing protocol includes cup-loading sample application at t
Autor:
Hormoz Ehya, Phillip D. Kim, Min Huang, James C. Watson, Bhavinkumar B. Patel, Kelly A. Jones, Anthony T. Yeung, John P. Hoffman, Jeffrey L. Tokar, Karthik Devarajan, Kathryn T. Chen
Considerable effort has been made to identify biomarkers of interest in pancreatic cancer for diagnosis and prognosis. Pancreatic cancer is a deadly malignancy and the mainstay of treatment remains complete surgical resection. Unfortunately, most pan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32657ef8c831b33a770ad939ecf16b94
https://europepmc.org/articles/PMC3859961/
https://europepmc.org/articles/PMC3859961/
Autor:
Steven G. Kelsen, Phillip D. Kim, Kelly A. Jones, Alan S. Braverman, Salim Merali, Russell P. Bowler, Carlos A. Barrero, Dian Er Chen, Bhavinkumar B. Patel, Anthony T. Yeung
Immunodepletion of abundant plasma proteins increases the depth of proteome penetration by mass spectrometry. However, the nature and extent of immunodepletion and the effect of off-target depletion on the quantitative comparison of the residual prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42844936da2da09246af9af7f8e146e
https://europepmc.org/articles/PMC3518753/
https://europepmc.org/articles/PMC3518753/
Isobaric multiplexed quantitative proteomics can complement high-resolution sample isolation techniques. Here, we report a simple workflow exponentially modified protein abundance index (emPAI)-MW deconvolution (EMMOL) for normalizing isobaric report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fbf630aab0438562a55efad536ceba
https://europepmc.org/articles/PMC3313697/
https://europepmc.org/articles/PMC3313697/
Autor:
Eileen Ke, James C. Watson, Xin Ming Li, Nancy A. Young, Minhhuyen Nguyen, Oleh Haluszka, Steven J. Cohen, David S. Weinberg, John P. Hoffman, Tiffany Liu, Bhavinkumar B. Patel, Samuel Litwin, Anthony T. Yeung, Hormoz Ehya, Jeffrey L. Tokar, Neal J. Meropol
There are currently no diagnostic indicators that are consistently reliable, obtainable, and conclusive for diagnosing and risk-stratifying pancreatic cysts. Proteomic analyses were performed to explore pancreatic cyst fluids to yield effective diagn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf0360f1555c427bd0f5ea0ad1a1e80
https://europepmc.org/articles/PMC2681236/
https://europepmc.org/articles/PMC2681236/
Autor:
Bhavinkumar B, Patel, Yin A, He, Xin-Ming, Li, Andrey, Frolov, Lisa, Vanderveer, Carolyn, Slater, Russell J, Schilder, Margaret, von Mehren, Andrew K, Godwin, Anthony T, Yeung
Publikováno v:
Cancer genomicsproteomics. 5(3-4)
Imatinib mesylate (Gleevec, Novartis, Basel, Switzerland) is a small-molecule tyrosine kinase inhibitor with activity against ABL, BCR-ABL, c-KIT, and PDGFR alpha. Several clinical trials have evaluated the efficacy and safety of imatinib in patients