Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bhavini Kumari"'
Autor:
Bhavini Kumari, Alaa Huwaidi, Gabriel Robert, Pierre Cloutier, Andrew D. Bass, Léon Sanche, J. Richard Wagner
Publikováno v:
The Journal of Physical Chemistry B. 126:5175-5184
Understanding the details of DNA damage caused by high-energy particles or photons is complicated by the multitude of reactive species, arising from the ionization and dissociation of H
Autor:
Léon Sanche, Alaa Huwaidi, Gabriel Robert, Brigitte Guérin, J. Richard Wagner, Bhavini Kumari
Publikováno v:
The Journal of Physical Chemistry Letters. 12:9947-9954
The presence of gold nanoparticles (AuNPs) greatly enhances the formation of DNA damage when exposed to therapeutic X-rays. Three types of DNA damage are assessed in irradiated DNA by enzymatic digestion coupled to liquid chromatography tandem mass s
Autor:
Bhavini Kumari, Prolay Das, Kaki Raveendra Babu, Topi Ghosh, Faiz Ahmed Khan, Richa Nigam, Roy Anindya
Publikováno v:
Chemical biologydrug designREFERENCES. 97(6)
DNA alkylation damage, emanating from the exposure to environmental alkylating agents or produced by certain endogenous metabolic processes, affects cell viability and genomic stability. Fe(II)/2-oxoglutarate-dependent dioxygenase enzymes, such as Es
Autor:
Bhavini Kumari, Roy Anindya, Faiz Ahmed Khan, Deepa Akula, Topi Ghosh, Richa Nigam, Subha Narayan Rath, Kaki Raveendra Babu, Prolay Das
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:4100-4112
The mammalian AlkB homologue-3 (AlkBH3) is a member of the dioxygenase family of enzymes that in humans is involved in DNA dealkylation repair. Because of its role in promoting tumor cell proliferation and metastasis of cancer, extensive efforts are
Publikováno v:
Journal of Biosciences. 43:575-583
5,6-Dihydroxy-5,6-dihydrothymine (thymine glycol) and 7,8-dihydro-8-oxo-20-deoxyguanosine (8-oxodG) are major DNA damage lesions produced by endogenous oxidative stress, as well as inflicted by carcinogens and ionizing radiation. The processing of Tg
Publikováno v:
RSC Advances. 8:17921-17926
The occurrence of 7,8-dihydro-8-oxo-2'deoxyguanosine (8-oxodG), thymine glycol:guanine (Tg:G) mismatch and abasic site DNA damage lesions in close proximity induce repair refractive multicomponent clustered DNA damage. Herein, the influence of abasic
Autor:
Abhishek Mandal, Priyanka H. Mazire, Prolay Das, Amit Roy, Bhavini Kumari, Sachidananda Behera, Pradeep Das, Payel Ghosh, Bidyut Purkait
Publikováno v:
Parasitology International. 82:102287
The global prevalence of HIV is a major challenge for the control of visceral leishmaniasis. Although the effectiveness and usefulness of amprenavir (APV) are well studied in anti-retroviral regimens, very little is known on HIV/VL-co-infected patien
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 157
G-quadruplexes are secondary DNA structures frequently found in telomeres and DNA sequences related to gene regulation, etc. Herein, we report a label free, sensitive and visually detectable fluorescence based biosensing platform for the detection of
Publikováno v:
RSC Advances. 5:23691-23698
Closely located multiple abasic sites or clustered abasic sites are highly mutagenic and potentially cytotoxic. They have been found to be repair resistant in several in vitro studies. We studied the efficiency of the repair of clustered abasic sites
Autor:
Nirmalendu Biswas, Shamba Chatterjee, Prolay Das, Tapas Ghosh, Nayim Sepay, Debashis Patra, Bhavini Kumari, Michael G. B. Drew
Publikováno v:
RSC Advances. 5:92456-92472
A new series of mixed-ligand oxidovanadium(V) complexes [VVO(HL1–4)(hq)] (1–4) have been synthesized using 2-hydroxybenzoylhydrazones of 2-hydroxyacetophenone and its 5-substituted derivatives (H3L1–4) along with 8-hydroxyquinoline (Hhq) as co-