An inhibitor of RORγ for chronic pulmonary obstructive disease treatment

Autor: Harshada Desai, Megha Marathe, Varada Potdar, Prabhakar Tiwari, Ashwini Joshi, Sheetal R. Kadam, Arti Rajesh Joshi, Abhay Kulkarni, Vikram Bhosale, Avinash Hadambar, Bhavik Lodhiya, Venkatesha Udupa, Dayanidhi Behera, Sachin S. Chaudhari, Sanjib Das, Malini Bajpai, Nagaraj Gowda, Pravin S. Iyer

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract The role of RORγ as a transcription factor for Th17 cell differentiation and thereby regulation of IL-17 levels is well known. Increased RORγ expression along with IL-17A levels was observed in animal models, immune cells and BAL fluid of

Externí odkaz: https://doaj.org/article/a7d1fc806fe64770a823646dd30ddaee

An inhibitor of RORγ for chronic pulmonary obstructive disease treatment.

Autor: Desai, Harshada¹ (AUTHOR), Marathe, Megha¹ (AUTHOR), Potdar, Varada¹ (AUTHOR), Tiwari, Prabhakar¹ (AUTHOR), Joshi, Ashwini¹ (AUTHOR), Kadam, Sheetal R.¹ (AUTHOR), Joshi, Arti Rajesh¹ (AUTHOR), Kulkarni, Abhay¹ (AUTHOR), Bhosale, Vikram¹ (AUTHOR), Hadambar, Avinash¹ (AUTHOR), Lodhiya, Bhavik¹ (AUTHOR), Udupa, Venkatesha² (AUTHOR), Behera, Dayanidhi³ (AUTHOR), Chaudhari, Sachin S.⁴ (AUTHOR), Das, Sanjib⁴ (AUTHOR), Bajpai, Malini¹ (AUTHOR) malini.bajpai@glenmarkpharma.com, Gowda, Nagaraj^1,3 (AUTHOR), Iyer, Pravin S.⁵ (AUTHOR)

Publikováno v: Scientific Reports. 5/24/2022, Vol. 12 Issue 1, p1-15. 15p.