Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bhavik Chouhan"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 211-221 (2020)
A structurally identifiable micro‐rate constant mechanistic model was used to describe the interaction between pitavastatin and eltrombopag, with improved goodness‐of‐fit values through comeasurement of pitavastatin and eltrombopag. Transporter
Externí odkaz:
https://doaj.org/article/a5f53b308f794671b966c68b6dd7040b
Autor:
Bhavik Chouhan, Dominic P. Williams, Magnus Söderberg, James W. Dear, Catherine C. Bell, Håkan Andersson, Linda C. Andersson
Publikováno v:
Archives of Toxicology
Bell, C C, Chouhan, B, Andersson, L C, Andersson, H, Dear, J, Williams, D P & Soderberg, M 2020, ' Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity. ', Archives of toxicology . https://doi.org/10.1007/s00204-020-02682-w)
Bell, C C, Chouhan, B, Andersson, L C, Andersson, H, Dear, J, Williams, D P & Soderberg, M 2020, ' Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity. ', Archives of toxicology . https://doi.org/10.1007/s00204-020-02682-w)
In addition to hepatocytes, the liver comprises a host of specialised non-parenchymal cells which are important to consider in the development of in vitro models which are both physiologically and toxicologically relevant. We have characterized a 3D
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 211-221 (2020)
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 211-221 (2020)
A structurally identifiable micro‐rate constant mechanistic model was used to describe the interaction between pitavastatin and eltrombopag, with improved goodness‐of‐fit values through comeasurement of pitavastatin and eltrombopag. Transporter
Autor:
Stanley E. Lazic, Linda C. Andersson, Alison J. Foster, Helen Rollison, Sophie L. Regan, Geraldine A. Hamilton, Malin Darnell, Bhavik Chouhan, Jonathan Cairns, Dominic P. Williams, Abhishek Srivastava, Lorna Ewart, Paul Morgan, Kyung-Jin Jang, Sara Amberntsson, Jonathan E. Rubins, Konstantia Kodella, Debora B. Petropolis
Publikováno v:
Archives of toxicology. 93(4)
Drug-induced liver injury remains a frequent reason for drug withdrawal. Accordingly, more predictive and translational models are required to assess human hepatotoxicity risk. This study presents a comprehensive evaluation of two promising models to
Autor:
Paul Morgan, Malin Darnell, Geraldine A. Hamilton, Sara Amberntsson, Helen Rollison, Lorna Ewart, Alison J. Foster, Dominic P. Williams, Kyung-Jin Jang, Sophie L. Regan, Linda C. Andersson, Jonathan E. Rubins, Abhishek Srivastava, Bhavik Chouhan, Konstantia Kodella, Debora B. Petropolis
Publikováno v:
Toxicology Letters. 295:S66