Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bhavana Nayer"'
Autor:
Bhavana Nayer, Jean L. Tan, Yasmin K. Alshoubaki, Yen-Zhen Lu, Julien M. D. Legrand, Sinnee Lau, Nan Hu, Anthony J. Park, Xiao-Nong Wang, Daniela Amann-Zalcenstein, Peter F. Hickey, Trevor Wilson, Gisela A. Kuhn, Ralph Müller, Ajithkumar Vasanthakumar, Shizuo Akira, Mikaël M. Martino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Regulatory T cells (Tregs) are crucial immune cells for tissue repair and regeneration. However, their potential as a cell-based regenerative therapy is not yet fully understood. Here, we show that local delivery of exogenous Tregs into inju
Externí odkaz:
https://doaj.org/article/f42f79ea96ac4536ad48ec4b75f69576
Autor:
Yasmin K. Alshoubaki, Bhavana Nayer, Yen-Zhen Lu, Ekaterina Salimova, Sin Nee Lau, Jean L. Tan, Daniela Amann-Zalcenstein, Peter F. Hickey, Gonzalo del Monte-Nieto, Ajithkumar Vasanthakumar, Mikaël M. Martino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Regulatory T cells (Tregs) are key immune regulators that have shown promise in enhancing cardiac repair post-MI, although the mechanisms remain elusive. Here, we show that rapidly increasing Treg number in the circulation post-MI via system
Externí odkaz:
https://doaj.org/article/a905ba98718746ceb7e2cdf602aafd25
Autor:
Jean L. Tan, Blake Lash, Rezvan Karami, Bhavana Nayer, Yen-Zhen Lu, Celeste Piotto, Ziad Julier, Mikaël M. Martino
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Tan, Lash et al. show that blocking the Interleukin-1 receptor promotes rapid wound closure in diabetic mice. They engineered a matrix binding form of Interleukin-1 receptor antagonist (IL-1Ra) that has the ability of precise localisation and retenti
Externí odkaz:
https://doaj.org/article/d69e7e9bda4641d3aec93935b49ff999
Autor:
Pradeep A. Subramani, Neha Vartak-Sharma, Seetha Sreekumar, Pallavi Mathur, Bhavana Nayer, Sushrut Dakhore, Sowmya K. Basavanna, Devaiah M. Kalappa, Ramya V. Krishnamurthy, Benudhar Mukhi, Priyasha Mishra, Noriko Yoshida, Susanta Kumar Ghosh, Radhakrishan Shandil, Shridhar Narayanan, Brice Campo, Kouichi Hasegawa, Anupkumar R. Anvikar, Neena Valecha, Varadharajan Sundaramurthy
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Abstract Background Vivax malaria is associated with significant morbidity and economic loss, and constitutes the bulk of malaria cases in large parts of Asia and South America as well as recent case reports in Africa. The widespread prevalence of vi
Externí odkaz:
https://doaj.org/article/dbb1ab7ecd984ef1a6242523f8b7cfcd
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Over the past two decades, human embryonic stem cells (hESCs) have gained attention due to their pluripotent and proliferative ability which enables production of almost all cell types in the human body in vitro and makes them an excellent tool to st
Externí odkaz:
https://doaj.org/article/115260f1e9b64a408c76716023f98cf3
Publikováno v:
Stem cells translational medicine. 11(3)
Numerous components of the immune system, including inflammatory mediators, immune cells and cytokines, have a profound modulatory effect on the homeostatic regulation and regenerative activity of endogenous stem cells and progenitor cells. Thus, und
Autor:
Bhavana Nayer, Kouichi Hasegawa, Jonathan C. Li, Subhanwita Sakar-Dey, Winita Hardikar, Kevin X. Lau, Karl Trounson, Alison Farley, David R. Braxton, Tatsuhiko Ikeda, Martin F. Pera
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
The Sialyl Lewis A antigen, or CA 19-9, is the prototype serum biomarker for adenocarcinoma of the pancreas. Despite extensive clinical study of CA 19-9 in gastrointestinal malignancies, surprisingly little is known concerning the specific cell types
Autor:
Mikaël M. Martino, Blake Lash, Bhavana Nayer, Ziad Julier, Celeste Piotto, Rezvan Karami, Jean Tan, Yen-Zhen Lu
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Chronic wounds are a major clinical problem where wound closure is prevented by pathologic factors, including immune dysregulation. To design efficient immunotherapies, an understanding of the key molecular pathways by which immunity impairs wound he
Autor:
Anthony Park, Mikaël M. Martino, Kenta Maruyama, Shizuo Akira, Rezvan Karami, Yen-Zhen Lu, Bhavana Nayer, Ziad Julier, Gisela A. Kuhn, Ralph Müller
Publikováno v:
Science Advances, 6 (24)
Science Advances
Science Advances
A novel engineered form of interleukin-1 receptor antagonist augments the regenerative activity of recombinant growth factors.
Although growth factors (GFs) are key molecules for regenerative medicine, their use has been limited by issues associ
Although growth factors (GFs) are key molecules for regenerative medicine, their use has been limited by issues associ
Autor:
Shridhar Narayanan, Neena Valecha, Kouichi Hasegawa, Priyasha Mishra, Anupkumar R. Anvikar, Seetha Sreekumar, Radhakrishan Shandil, Neha Vartak-Sharma, Pallavi Mathur, Benudhar Mukhi, Pradeep Annamalai Subramani, Bhavana Nayer, Sowmya Kanchanahalli Basavanna, Noriko Yoshida, Sushrut Dakhore, Brice Campo, Ramya Vadageri Krishnamurthy, Varadharajan Sundaramurthy, Susanta Kumar Ghosh, Devaiah Monnanda Kalappa
Publikováno v:
Malaria Journal
Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Background Vivax malaria is associated with significant morbidity and economic loss, and constitutes the bulk of malaria cases in large parts of Asia and South America as well as recent case reports in Africa. The widespread prevalence of vivax is a