Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bhavana Muralidharan"'
Autor:
Varun Suresh, Bhavana Muralidharan, Saurabh J Pradhan, Mahima Bose, Leora D'Souza, Arpan Parichha, Puli Chandramouli Reddy, Sanjeev Galande, Shubha Tole
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010874 (2023)
In the mammalian cerebral cortex, the hippocampal primordium (Hcp) occupies a discrete position in the dorsal telencephalic neuroepithelium adjacent to the neocortical primordium (Ncp). We examined transcriptomic and chromatin-level features that dis
Externí odkaz:
https://doaj.org/article/a858fe0190774b5489ca95fc089e40fb
Publikováno v:
Journal of Experimental Neuroscience, Vol 12 (2018)
We established an efficient cell culture assay that permits combinatorial genetic perturbations in hippocampal progenitors to examine cell-autonomous mechanisms of fate specification. The procedure begins with ex vivo electroporation of isolated, int
Externí odkaz:
https://doaj.org/article/0c8bbc1d7fa14882816d006300fb6bb2
Autor:
Bhavana Muralidharan
Publikováno v:
Int J Dev Biol
The brain is the seat of all higher-order functions in the body. Brain development and the vast array of neurons and glia it produces is a baffling mystery to be studied. Neuroscientists using a vast number of model systems have been able to crack ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846a7afefc70e5ca4dd7eaffcf0416ba
https://doi.org/10.1387/ijdb.190204bm
https://doi.org/10.1387/ijdb.190204bm
Autor:
Bhavana Muralidharan
Mouse model systems of human neurological disorders though useful are not always accurate because mouse and human brains have considerable differences in development, genetics, and physiology. They vary considerably in their embryonic brain developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b5fec90f866522b51dc15fc38c03afe
https://doi.org/10.1016/b978-0-12-821972-0.00013-7
https://doi.org/10.1016/b978-0-12-821972-0.00013-7
Autor:
Ravichandran Vijaya Abinaya, Vidhu Aeri, Gunjan Arora, Kriti Arora, Rajkumar Chakraborty, Suresh Kumar Chalapareddy, Nitin Chaudhary, Munish Chhabra, Ravindresh Chhabra, Debika Datta, Pawan Dhar, Nitu Dogra, Rajan Guha, Debleena Guin, Yasha Hasija, Deepshikha Pande Katare, Ritushree Kukreti, Yatender Kumar, Priyanka Majumder, Ruchi Jakhmola Mani, Siddharth Manvati, Savita Mishra, Bhavana Muralidharan, Richa Nayak, Ajit Kumar Rai, S. Ramachandran, Srividhya Ravichandran, Apu Kumar Saha, Samvedna Saini, Andaleeb Sajid, Neeraj Kumar Satija, Mritunjay Saxena, Vidhu Sharma, Pooja Singh, Sarita Thakran, Sindhuri Upadrasta, Gaurav Verma, Neeraj Verma, Pragasam Viswanathan, Vikas Yadav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::011b53235b9bcbb7b92b770599b7e2d2
https://doi.org/10.1016/b978-0-12-821972-0.00023-x
https://doi.org/10.1016/b978-0-12-821972-0.00023-x
Autor:
Bhavana Muralidharan, Zeba Khatri, Hari Padmanabhan, Archana Iyer, Shubha Tole, Geeta Godbole, Upasana Maheshwari, Veena Kinare, Tooba Khan
Protein cofactor Ldb1 regulates cell fate specification by interacting with LIM-homeodomain (LIM-HD) proteins in a tetrameric complex consisting of an LDB:LDB dimer that bridges two LIM-HD molecules, a mechanism first demonstrated in theDrosophilawin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6acc069367d49c8f687370252bc7903
https://doi.org/10.1101/2020.08.24.265207
https://doi.org/10.1101/2020.08.24.265207
Publikováno v:
Neuron
Hexanucleotide GGGGCC repeat expansion in C9ORF72 is the most prevalent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). One pathogenic mechanism is the aberrant accumulation of dipeptide repeat (DPR) proteins p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f8e8807d574c866782c3a3c3c8b2a0
https://pubmed.ncbi.nlm.nih.gov/31587919
https://pubmed.ncbi.nlm.nih.gov/31587919
Publikováno v:
Neurochem Int
The diverse number of neurons in the cerebral cortex are generated during development by neural stem cells lining the ventricle, and they continue maturing postnatally. Dynamic chromatin regulation in these neural stem cells is a fundamental determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5c9463088a9abd125cf2db2e751809
https://doi.org/10.1016/j.neuint.2021.105055
https://doi.org/10.1016/j.neuint.2021.105055
Autor:
Bhavana Muralidharan, Agasthya Suresh, Basabdatta Roy, Sanjeev Galande, Shubha Tole, Saurabh J. Pradhan, Eric Bellefroid, Veena Kinare, Leora D'Souza, Marc Keruzore, Ashwin S. Shetty, Krishanpal Karmodiya, Upasana Maheshwari
Publikováno v:
The Journal of neuroscience, 37 (46
The Journal of Neuroscience
The Journal of Neuroscience
Regulation of the neuron-glia cell-fate switch is a critical step in the development of the CNS. Previously, we demonstrated that Lhx2 is a necessary and sufficient regulator of this process in the mouse hippocampal primordium, such that Lhx2 overexp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abeac8bef6b29783a328a0536237f29
https://doi.org/10.1523/jneurosci.1535-17.2017
https://doi.org/10.1523/jneurosci.1535-17.2017