Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Bhav Harshad Parikh"'
Autor:
Kakkad Regha, Mayuri Bhargava, Abdurrahmaan Al-Mubaarak, Chou Chai, Bhav Harshad Parikh, Zengping Liu, Claudine See Wei Wong, Walter Hunziker, Kah Leong Lim, Xinyi Su
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Retinal pigment epithelial (RPE) cell dysfunction and death are characteristics of age-related macular degeneration. A promising therapeutic option is RPE cell transplantation. Development of clinical grade stem-cell derived RPE requires eff
Externí odkaz:
https://doaj.org/article/3bd7339aa071480992c9732da3df4a0f
Autor:
Bhav Harshad Parikh, Zengping Liu, Paul Blakeley, Qianyu Lin, Malay Singh, Jun Yi Ong, Kim Han Ho, Joel Weijia Lai, Hanumakumar Bogireddi, Kim Chi Tran, Jason Y. C. Lim, Kun Xue, Abdurrahmaan Al-Mubaarak, Binxia Yang, Sowmiya R, Kakkad Regha, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Zhongxing Zhang, Anand D. Jeyasekharan, Veluchamy Amutha Barathi, Weimiao Yu, Kang Hao Cheong, Timothy A. Blenkinsop, Walter Hunziker, Gopal Lingam, Xian Jun Loh, Xinyi Su
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
One common cause of vision loss after retinal detachment surgery is retinal scarring. Here the authors demonstrate that a bio-functional polymer can prevent retinal scarring by suppression of epithelial-mesenchymal transition and hyper-proliferation
Externí odkaz:
https://doaj.org/article/29658a3e9704480d80f0623a65432050
Autor:
Pradeep Gautam, Kiyofumi Hamashima, Ying Chen, Yingying Zeng, Bar Makovoz, Bhav Harshad Parikh, Hsin Yee Lee, Katherine Anne Lau, Xinyi Su, Raymond C. B. Wong, Woon-Khiong Chan, Hu Li, Timothy A. Blenkinsop, Yuin-Han Loh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
A comprehensive analysis of the ocular networks among various tissues is necessary to understand eye physiology in health and disease. Here the authors present a multi-species single-cell transcriptomic atlas consisting of cells of the cornea, iris,
Externí odkaz:
https://doaj.org/article/90aabc87256046d2ac0a0db19b2e943e
Autor:
Swathi Lingam, Zengping Liu, Binxia Yang, Wendy Wong, Bhav Harshad Parikh, Jun Yi Ong, Debbie Goh, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Gavin S. W. Tan, Graham E. Holder, Kakkad Regha, Veluchamy Amutha Barathi, Walter Hunziker, Gopal Lingam, Xianmin Zeng, Xinyi Su
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Retinal regenerative therapies hold great promise for the treatment of inherited retinal degenerations (IRDs). Studies in preclinical lower mammal models of IRDs have suggested visual improvement following retinal photoreceptor pr
Externí odkaz:
https://doaj.org/article/ebb00a72f8324335bf6cabbb07433c97
Autor:
Raji Rajesh Lenin, Yi Hui Koh, Zheting Zhang, Yan Zhuang Yeo, Bhav Harshad Parikh, Ivan Seah, Wendy Wong, Xinyi Su
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8763 (2023)
Retinal pigment epithelial (RPE) cell dysfunction is a key driving force of AMD. RPE cells form a metabolic interface between photoreceptors and choriocapillaris, performing essential functions for retinal homeostasis. Through their multiple function
Externí odkaz:
https://doaj.org/article/f4ba54a70ba5444c8daed748c7c8560b
Autor:
Siew Yin Chan, Benjamin Qi Yu Chan, Zengping Liu, Bhav Harshad Parikh, Kangyi Zhang, Qianyu Lin, Xinyi Su, Dan Kai, Wee Sim Choo, David James Young, Xian Jun Loh
Publikováno v:
ACS Omega, Vol 2, Iss 12, Pp 8959-8968 (2017)
Externí odkaz:
https://doaj.org/article/337fdceae3a64688866204c9225f7d57
Autor:
Rebekah Pei Ting Tan, Jayce Jian Wei Cheng, Bhav Harshad Parikh, Joey Hui Min Wong, Beatrice W. Soh, Jun Jie Chang, Kim Chi Tran, Yuan Lee, Pei Lin Chee, Yi Jian Boo, Qianyu Lin, Lu Jiang, Xinyi Su, Jason Y.C. Lim, Xian Jun Loh, Kun Xue
Publikováno v:
ACS Applied Polymer Materials. 4:5091-5102
Autor:
Valerie Ow, Jun Jie Chang, Wai Hon Chooi, Yi Jian Boo, Rebekah P.T. Tan, Joey H.M. Wong, Bhav Harshad Parikh, Xinyi Su, Shi Yan Ng, Xian Jun Loh, Kun Xue
Publikováno v:
Carbohydrate polymers. 302
Hydrogels with more than one mode of crosslinking have gained interest due to improved control over hydrogel properties such as mechanical strength using multiple stimuli. In this work, sodium alginate was covalently conjugated onto thermoresponsive
Autor:
Zengping Liu, Bhav Harshad Parikh, Xinyi Su, Karen Yuanting Tang, Kun Xue, Soo Lin Wong, Qianyu Lin, Jason Y. C. Lim, Xian Jun Loh
Publikováno v:
ACS Applied Bio Materials. 3:9043-9053
Polymeric hydrogels are promising biomaterials to be used as vitreous tamponade in the eye. However, while the clinical need and the required attributes of a vitreous replacement hydrogel are clear, there is a major gap in understanding the various p
Autor:
Bhav Harshad Parikh, Zengping Liu, Paul Blakeley, Qianyu Lin, Malay Singh, Jun Yi Ong, Kim Han Ho, Joel Weijia Lai, Hanumakumar Bogireddi, Kim Chi Tran, Jason Y. C. Lim, Kun Xue, Abdurrahmaan Al-Mubaarak, Binxia Yang, Sowmiya R, Kakkad Regha, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Zhongxing Zhang, Anand D. Jeyasekharan, Veluchamy Amutha Barathi, Weimiao Yu, Kang Hao Cheong, Timothy A. Blenkinsop, Walter Hunziker, Gopal Lingam, Xian Jun Loh, Xinyi Su
Publikováno v:
Nature communications. 13(1)
One common cause of vision loss after retinal detachment surgery is the formation of proliferative and contractile fibrocellular membranes. This aberrant wound healing process is mediated by epithelial-mesenchymal transition (EMT) and hyper-prolifera