Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Bhaumik B, Patel"'
Autor:
Pavani Pingali, Y. Jeffrey Wu, Rio Boothello, Chetna Sharon, Howard Li, Srinivas Sistla, Nehru Viji Sankaranarayanan, Umesh R. Desai, Anh T. Le, Robert C. Doebele, Leslie L. Muldoon, Bhaumik B. Patel, Alexander Neuwelt
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 3, Pp 348-359 (2021)
High-dose acetaminophen (AAP) with delayed rescue using n-acetylcysteine (NAC), the FDA-approved antidote to AAP overdose, has demonstrated promising antitumor efficacy in early phase clinical trials. However, the mechanism of action (MOA) of AAP's a
Externí odkaz:
https://doaj.org/article/a566ac75bb6b41de905d39f86be028a1
Autor:
Shravan Morla, Ongolu Ravikumar, Connor O’Hara, Rio Boothello, Alberto Vera, Elsamani I. Abdelfadiel, Rawan Fayyad, Daniel K. Afosah, Chetna Sharon, Leopoldo Fernandez, Syed Ammer Shah, Bhaumik B. Patel, Umesh R. Desai
Publikováno v:
Journal of Medicinal Chemistry. 66:1321-1338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e61143d660717d1e22ab43b710273bd
https://doi.org/10.1021/acs.jmedchem.2c01511
https://doi.org/10.1021/acs.jmedchem.2c01511
Autor:
Bhaumik B. Patel, Umesh R. Desai, H. Robert Lippman, Donald F. Brophy, Shravan Morla, Elsamani I. Abdelfadiel, Chetna Sharon, Nirmita J. Patel, Rio S. Boothello
The 16 page composite document outlines supplemental methods as well as Figures. Fig S1: a- In vivo tumor formation assay with subcutaneous injections of (2,000) Dual hi HT-29 cells show high tumor forming efficiency of Dual hi cells compared to unso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb7fdafd2a3267268ec88591383c8dd
https://doi.org/10.1158/1535-7163.22509093.v1
https://doi.org/10.1158/1535-7163.22509093.v1
Autor:
Adhip P.N. Majumdar, Ramzi M. Mohammad, Arun K. Rishi, Fazlul H. Sarkar, Bhaumik B. Patel, Jianhua Du, Jayanta K. Das, Shailender S. Kanwar, Amro Aboukameel, Yingjie Yu, Jyoti Nautiyal
Many solid tumors, including breast cancer, show increased activation of several growth factor receptors, specifically epidermal growth factor receptor (EGFR) and its family members as well as c-Src, a nonreceptor tyrosine kinase that promotes prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeada2741b34d1bebdca566b877512a
https://doi.org/10.1158/1535-7163.c.6531651
https://doi.org/10.1158/1535-7163.c.6531651
Autor:
Adhip P.N. Majumdar, Ramzi M. Mohammad, Arun K. Rishi, Fazlul H. Sarkar, Bhaumik B. Patel, Jianhua Du, Jayanta K. Das, Shailender S. Kanwar, Amro Aboukameel, Yingjie Yu, Jyoti Nautiyal
Supplementary Data from ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b21d86fb2f776f5e5ff160715180e7
https://doi.org/10.1158/1535-7163.22484913
https://doi.org/10.1158/1535-7163.22484913
Publikováno v:
Indian Journal of Horticulture. 79:99-108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f8b4f6f890d898e0745348abd85a587
https://doi.org/10.5958/0974-0112.2022.00015.9
https://doi.org/10.5958/0974-0112.2022.00015.9
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171619 (2017)
Glycosaminoglycans (GAGs) are key natural biopolymers that exhibit a range of biological functions including growth and differentiation. Despite this multiplicity of function, natural GAG sequences have not yielded drugs because of problems of hetero
Externí odkaz:
https://doaj.org/article/a817105fbb7b46249a7bfc0a491725be
Autor:
Rio S. Boothello, Nehru Viji Sankaranarayanan, Jyothi C. Sistla, Balaji Nagarajan, Chetna Sharon, John E. Chittum, Rabiya Y. Niyaz, Swarnali Roy, Aditi Nandi, Connor P. O'Hara, Rahaman Navaz Gangji, Daniel K. Afosah, Ravikumar Ongolu, Bhaumik B. Patel, Umesh R. Desai
Publikováno v:
Angewandte Chemie (International ed. in English). 61(49)
The insulin-like growth factor-1 receptor (IGF-1R) is a receptor tyrosine kinase (RTK) that plays critical roles in cancer. Microarray, computational, thermodynamic, and cellular imaging studies reveal that activation of IGF-1R by its cognate ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec96f729639d008b57578e382f710ff
https://pubmed.ncbi.nlm.nih.gov/36205924
https://pubmed.ncbi.nlm.nih.gov/36205924
Autor:
Umesh R. Desai, Anh T. Le, Howard Li, Leslie L. Muldoon, Chetna Sharon, Bhaumik B. Patel, Srinivas Sistla, Nehru Viji Sankaranarayanan, Y. Jeffrey Wu, Pavani Pingali, Alexander J. Neuwelt, Rio S. Boothello, Robert C. Doebele
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 3, Pp 348-359 (2021)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
High-dose acetaminophen (AAP) with delayed rescue using n-acetylcysteine (NAC), the FDA-approved antidote to AAP overdose, has demonstrated promising antitumor efficacy in early phase clinical trials. However, the mechanism of action (MOA) of AAP's a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e22dc1951d05ebf530d300603e7d238
http://www.sciencedirect.com/science/article/pii/S1476558621000075
http://www.sciencedirect.com/science/article/pii/S1476558621000075
Publikováno v:
Cancer Research. 83:1808-1808
Background: Immune-modulating therapies have limited efficacy in colorectal cancers (CRC). This resistance to treatment is attributed to low neoantigen expression, and the inability of T cells to kill HLA-I negative tumor cells, especially cancer ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f471ebb4b30a88d89712cb7ed47b3a11
https://doi.org/10.1158/1538-7445.am2023-1808
https://doi.org/10.1158/1538-7445.am2023-1808