Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bhaumik A. Pandya"'
Autor:
Stephen J. Wood, Bhaumik A. Pandya
Publikováno v:
2020 Medicinal Chemistry Reviews ISBN: 9781734427400
2020 Medicinal Chemistry Reviews
2020 Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c73f136cea4fbe01b42d63fa5d4a1f1f
https://doi.org/10.29200/acsmedchemrev-v55.ch18
https://doi.org/10.29200/acsmedchemrev-v55.ch18
Publikováno v:
The Journal of Immunology. 204:240.7-240.7
Heat Shock Factor 1 (HSF1) is transcriptionally activated in response to a variety of environmental stressors. Data from our laboratory indicates that genetic inactivation of HSF1 significantly delays tumorigenesis in various tumor models. Increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7566d8632af61c8b540c6ac0b38be78b
https://doi.org/10.4049/jimmunol.204.supp.240.7
https://doi.org/10.4049/jimmunol.204.supp.240.7
Autor:
Vasu Chandrasekaran, Bernd Becker, Michael F. Mesleh, Johannes Zuegg, Christopher M. Liu, Mary Conrad, Craig Muldoon, Wim Meutermans, Bhaumik A. Pandya, Peter T. Rye, Terence Moy, Premraj Rajaratnam, You Seok Hwang
Publikováno v:
Chemical Biology & Drug Design. 87:190-199
Synthesis of bacterial cell wall peptidoglycan requires glycosyltransferase enzymes that transfer the disaccharide-peptide from lipid II onto the growing glycan chain. The polymerization of the glycan chain precedes cross-linking by penicillin-bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7651ab8e2766bdb0b82aaf66249fd280
https://doi.org/10.1111/cbdd.12662
https://doi.org/10.1111/cbdd.12662
Publikováno v:
Cancer Research. 79:1830-1830
Heat shock transcription factor 1 (HSF1) is normally activated in response to a variety of environmental stressors. Higher levels of HSF1 expression has been shown in many tumor types and this is associated with poor prognosis. Previous data from our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8361388a1b36e9d9d9e2603eaa908fa7
https://doi.org/10.1158/1538-7445.am2019-1830
https://doi.org/10.1158/1538-7445.am2019-1830
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(3)
Daptomycin is a highly effective lipopeptide antibiotic against Gram-positive pathogens. The presence of (2S, 3R) 3-methyl glutamic acid (mGlu) in daptomycin has been found to be important to the antibacterial activity. However the role of (2S, 3R) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ed5557f69fe00ba01a363ed6c1f9e7
https://pubmed.ncbi.nlm.nih.gov/28038833
https://pubmed.ncbi.nlm.nih.gov/28038833
Autor:
Katherine M. Poutsiaka, Lippa Blaise S, Haoqun Chandonnet, Timothy Hopper, Jing Zhang, Mustafa Varoglu, Jan Antoinette C. Romero, Sabrina Stucka, Jennifer Goss, Audrey Chan, Christian Baber, Brian Chamberlain, Bhaumik A. Pandya, Xin Zhang
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(14)
Irritable bowel diseases (IBD) such as Crohn's disease (CD) and ulcerative colitis (UC) are serious chronic diseases affecting millions of patients worldwide. Studies of human chemokine biology has suggested C-C chemokine receptor 9 (CCR9) may be a k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f76c35dc2c76efddca9b68935442f6c
https://pubmed.ncbi.nlm.nih.gov/27256913
https://pubmed.ncbi.nlm.nih.gov/27256913
Publikováno v:
Drug Repositioning: Bringing New Life to Shelved Assets and Existing Drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97579e82a47817037722c37ce5429d3b
https://doi.org/10.1002/9781118274408.ch10
https://doi.org/10.1002/9781118274408.ch10
Autor:
Haibo Liu, Patrick W. Faloon, Baudouin Gerard, Bridget K. Wagner, Erin Forbeck, Jeremy R. Duvall, Danny Hung-Chieh Chou, Bhaumik A. Pandya, Byung-Chul Suh, Lisa A. Marcaurelle
Publikováno v:
ACS Medicinal Chemistry Letters. 2:698-702
The synthesis of a stereochemically diverse library of medium-sized rings accessible via a 'build/couple/pair' strategy is described. Key aspects of the synthesis include S(N)Ar cycloetherification of a linear amine template to afford eight stereoiso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eb79c9ac69be710a461668f85cd568
https://doi.org/10.1021/ml200120m
https://doi.org/10.1021/ml200120m
Autor:
Maurice D. Lee, Bhaumik A. Pandya, Jean-Charles Marie, Haibo Liu, Baudouin Gerard, Lisa A. Marcaurelle
Publikováno v:
The Journal of Organic Chemistry. 76:1898-1901
All stereoisomers of a highly functionalized 2,3-unsaturated C-glycoside can be accessed in 10-100 g quantities from readily available starting materials and reagents in 3-7 steps. These chiral scaffolds contain three stereogenic centers along with o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db5a682dae9af5b56eca689b5d0b6fd
https://doi.org/10.1021/jo1022926
https://doi.org/10.1021/jo1022926