Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bhaskara R Madina"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123441 (2015)
Adaptation and survival of Trypanosoma brucei requires editing of mitochondrial mRNA by uridylate (U) insertion and deletion. Hundreds of small guide RNAs (gRNAs) direct the mRNA editing at over 3,000 sites. RNA editing is controlled during the life
Externí odkaz:
https://doaj.org/article/f020b05da86d4f799d75b92de3e933e8
Autor:
Manisha Menon, Carolina Chiale, Bijan Almassian, Michael D. Robek, John K. Rose, Timur O. Yarovinsky, Stephen W. Mason, Marie M. Krady, Safiehkhatoon Moshkani, Bhaskara R. Madina, Valerian Nakaar, Anasuya Chattopadhyay Pal
Publikováno v:
Vaccines
Volume 8
Issue 2
Vaccines, Vol 8, Iss 279, p 279 (2020)
Volume 8
Issue 2
Vaccines, Vol 8, Iss 279, p 279 (2020)
Virus-like vesicles (VLV) are hybrid vectors based on an evolved Semliki Forest virus (SFV) RNA replicon and the envelope glycoprotein (G) from vesicular stomatitis virus (VSV). Previously, we showed that VLV can be used to express protein antigens a
Autor:
Valerian Nakaar, Ayesha B. Alvero, Bijan Almassian, Timur O. Yarovinsky, Marie M. Krady, Bhaskara R. Madina, Gil Mor, Alexandra Fox
Publikováno v:
Cancer Research. 81:1150-1150
Background: Ovarian cancer is the most lethal of all gynecologic malignancies with a grim 5-year survival rate of ~47%. Mortality occurs in the setting of recurrent disease wherein the co-presentation of chemoresistance and carcinomatosis limits the
Autor:
Bhaskara R. Madina, Kepeng Wang, Marie M. Krady, Ju Chen, Bijan Almassian, Xianyong Ma, Timur O. Yarovinsky, Valerian Nakaar
Publikováno v:
Journal of Clinical Oncology. 39:e14560-e14560
e14560 Background: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in humans. Treatment of late-stage CRC remains ineffective, even with the use of latest immunotherapies. Oncolytic viruses have shown limited use for the t
Autor:
Marie M. Krady, Carolina Chiale, Safiehkhatoon Moshkani, Anasuya Chattopadhyay Pal, Michael D. Robek, Stephen W. Mason, Maria Haslip, Bijan Almassian, Bhaskara R. Madina, Timur O. Yarovinsky, Valerian Nakaar, John K. Rose, Xianyong Ma, Manisha Menon
Publikováno v:
iScience, Vol 21, Iss, Pp 391-402 (2019)
iScience
iScience
Summary Infections with hepatitis B virus (HBV) can initiate chronic hepatitis and liver injury, causing more than 600,000 deaths each year worldwide. Current treatments for chronic hepatitis B are inadequate and leave an unmet need for immunotherape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9996b29b85ce18f05f69f328b818bda7
https://doi.org/10.1101/491985
https://doi.org/10.1101/491985
Autor:
Kepeng Wang, Bhaskara R. Madina, Xiaoyang Ye, Bijan Almassian, Marie M. Krady, Ju Chen, Timur O. Yarovinsky, Xianyong Ma, Valerian Nakaar, Stephen W. Mason
Publikováno v:
Journal of Clinical Oncology. 38:e15210-e15210
e15210 Background: Colorectal cancer is the third deadliest of all cancers causing more than 50,000 deaths per year in the U.S. Oncolytic viruses have seen limited use for the treatment of cancers, and further improvement of these methods with immune
Autor:
Richard P. Metz, Bhaskara R. Madina, Blaine H. M. Mooers, Jorge Cruz-Reyes, Ralf Bundschuh, Vikas Kumar
Publikováno v:
RNA. 20:1142-1152
Mitochondrial mRNAs in kinetoplastids require extensive U-insertion/deletion editing that progresses 3′-to-5′ in small blocks, each directed by a guide RNA (gRNA), and exhibits substrate and developmental stage-specificity by unsolved mechanisms.
Autor:
James A. Wohlschlegel, Gokulan Kuppan, Sing-Hoi Sze, Yu-He Liang, Xinhua Ji, Bhaskara R. Madina, Laurie K. Read, Kurtis M. Downey, Ajay A. Vashisht, James C. Sacchettini, Jorge Cruz-Reyes
Publikováno v:
RNA. 17:1821-1830
The mitochondrial genome of kinetoplastids, including species of Trypanosoma and Leishmania, is an unprecedented DNA structure of catenated maxicircles and minicircles. Maxicircles represent the typical mitochondrial genome encoding components of the
Autor:
Bhaskara R. Madina, Michael Kinter, Kevin Ro, Alfredo J. Hernandez, Belinda Willard, James A. Wohlschlegel, Jorge Cruz-Reyes
Publikováno v:
Journal of Biological Chemistry. 285:1220-1228
Regulation of gene expression in kinetoplastid mitochondria is largely post-transcriptional and involves the orchestration of polycistronic RNA processing, 3′-terminal maturation, RNA editing, turnover, and translation; however, these processes rem
Autor:
Bhaskara R. Madina, Pankaj Chaturvedi, Lokendra Kumar Sharma, Rakesh Tuli, Rajender S. Sangwan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1774:1199-1207
Sterol glycosyltransferases catalyze the synthesis of diverse glycosterols in plants. Withania somnifera is a medically important plant, known for a variety of pharmacologically important withanolides and their glycosides. In this study, a novel 27be