Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bhaskar Kandagatla"'
Autor:
Christopher J. Cobley, Martin E. Fox, Vilas Hareshwar Dahanukar, Armando Carlone, Bhaskar Kandagatla, Ada Martinelli, Riccardo Carbone, Srinivas Oruganti, Luca Bernardi, Mariafrancesca Fochi
Publikováno v:
Chemistry – A European Journal. 21:19208-19222
In the context of a programme directed at the manufacture of telaprevir, eight possible approaches to its bicyclic α-amino acid core, based on organocatalytic enantioselective conjugate additions to cyclopent-1-enecarbaldehyde, were identified and p
Autor:
Vikas Gajare, Michael C. Lloyd, Martin E. Fox, Rashid Abdul Rehman Khan, Moses Babu Janagili, Veerabhadra Pratap Tadikonda, Bhaskar Kandagatla, Manpreet Singh, Rajesh Kumar Rapolu, Javed Iqbal, Malavika Banda, Sandip R. Khobare, Srinivasa Reddy Kallam, Rajender Datrika, Vilas Hareshwar Dahanukar, Siddaiah Vidavalur, Saikat Sen, Vishnuvardhan Reddy Eda, Srinivas Oruganti
Publikováno v:
Tetrahedron. 73:4285-4294
An efficient multi-gram synthesis of (1R,2S,5S)-methyl 6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate, a key chiral bicyclic proline fragment employed in the construction of the potent anti-HCV drug boceprevir, has been presented. The synthetic
Autor:
Rajesh Kumar Rapolu, Javed Iqbal, Narasimha Rao Nevuluri, Saikat Sen, Vilas Hareshwar Dahanukar, Bhaskar Kandagatla, Srinivas Oruganti
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 148:1477-1482
A convergent synthesis of the anti-coagulant drug apixaban has been efficiently demonstrated on a multi-gram scale. The synthetic route is noteworthy for its brevity and fact that it completely avoids the use of morpholine, a toxic and flammable reag
Autor:
Jakeer Pasha, Srinivas Oruganti, Saikat Sen, Sushmitha Bujji, Devyani Haldar, Bhaskar Kandagatla, Guru Pavan Kumar Seerapu, Srinivas Nanduri
Publikováno v:
Tetrahedron Letters. 56:2289-2292
Amberlyst® 15(H) has been shown for the first time to be effective as a greener catalyst in promoting the Povarov reaction between an imine, derived from the aryl/heteroaryl aldehydes and 1H-indazol-6-amine, and indole/5-bromo-1H-indole. Representat
Autor:
Srinivas Oruganti, Pallavi Rao, Manojit Pal, Rajesh Kumar Rapolu, Kottur Mohan Kumar, Ismail, Naveen Mulakayala, Bhaskar Kandagatla
Publikováno v:
Tetrahedron Letters. 53:6004-6007
A clean process has been developed for the ipso-hydroxylation of aryl and heteroaryl boronic acids to the corresponding phenols using commercially available and recyclable Amberlite IR-120 resin and aqueous hydrogen peroxide as an oxidizing agent. Th
Autor:
Anupama T. Row, Manika Pal Bhadra, Shasi V. Kalivendi, Debabrata Chowdhury, Swetha Pavani Rao, Partha P. Ghosh, Suman Asalla, Bhaskar Kandagatla, Prasenjit Mitra, Ramya S. Kuna, Utpal Bhadra, Ahamed Ibrahim, Srinivas Oruganti, Shravan Babu Girada
Publikováno v:
Scientific Reports
Dyslipidemia, particularly the elevated serum cholesterol levels, aggravate the pathophysiology of type 2 diabetes. In the present study we explored the relationship between fasting blood sugar and serum lipid parameters in human volunteers which rev
Autor:
Pallavi Rao, Chaitanya Mulakayala, Javed Iqbal, Chitta Suresh Kumar, Ismail, Naveen Mulakayala, Rajesh Kumar Rapolu, Bhaskar Kandagatla, Srinivas Oruganti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:5063-5066
A convenient and practical methodology for the synthesis of 2-aryl quinazolin-4(3H)-ones by the condensation of o-aminobenzamides with aromatic aldehydes under mild conditions using catalytic InCl3 with good yields and high selectivities. This method
Autor:
Srinivas Oruganti, Sushmitha Bujji, Guru Pavan Kumar Seerapu, Srinivas Nanduri, Devyani Haldar, Bhaskar Kandagatla, Jakeer Pasha, Saikat Sen
Publikováno v:
ChemInform. 46
Interestingly, compounds (IV) derived from 5-bromoindole (II) exhibit a higher degree of Sir-2 inhibition as compared to their counterparts, derived from indole.
Autor:
Vetukuri Venkata Naga Kali Vara Prasada Raju, Srinivas Oruganti, Sirigiri Chandrakanth Rao, Rakeshwar Bandichhor, Javed Iqbal, Bhaskar Kandagatla, Ganta Madhusudhan Reddy
Publikováno v:
Tetrahedron Letters. 53:7125-7127
Agomelatine was synthesized from 8-aminonaphthalen-2-ol by diazotization-iodination, formylation, C–C bond formation by nitroaldol and Pd/C hydrogenation of β-nitrovinylnaphthalene followed by N-acetylation. The route reported employs readily and
Autor:
Kottur Mohan Kumar, Srinivas Oruganti, Pallavi Rao, Ismail Ismail, Bhaskar Kandagatla, Naveen Mulakayala, Rajesh Kumar Rapolu, Manojit Pal
Publikováno v:
ChemInform. 44
Hydroxylation of arylboronic acids in the presence of recyclable, strongly acidic cross-linked Amberlite results in formation of the corresponding phenols in good to excellent yields within a short time.