Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Bhaskar Kallakury"'
Autor:
Danyal Daneshdoust, Mingjue Luo, Zaibo Li, Xiaokui Mo, Sahar Alothman, Bhaskar Kallakury, Richard Schlegel, Junran Zhang, Deliang Guo, Priscilla A. Furth, Xuefeng Liu, Jenny Li
Publikováno v:
Cells, Vol 12, Iss 19, p 2388 (2023)
Preclinical in vitro models play an important role in studying cancer cell biology and facilitating translational research, especially in the identification of drug targets and drug discovery studies. This is particularly relevant in breast cancer, w
Externí odkaz:
https://doaj.org/article/47684bde3c824ba0915d04da340bc0b9
Autor:
Jedson R. Liggett, Jiman Kang, Suman Ranjit, Olga Rodriguez, Katrina Loh, Digvijay Patil, Yuki Cui, Anju Duttargi, Sang Nguyen, Britney He, Yichien Lee, Kesha Oza, Brett S. Frank, DongHyang Kwon, Heng-Hong Li, Bhaskar Kallakury, Andrew Libby, Moshe Levi, Simon C. Robson, Thomas M. Fishbein, Wanxing Cui, Chris Albanese, Khalid Khan, Alexander Kroemer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type 1 Natural Killer T-cells (NKT1 cells) play a critical role in mediating hepatic ischemia-reperfusion injury (IRI). Although hepatic steatosis is a major risk factor for preservation type injury, how NKT cells impact this is understudied. Given N
Externí odkaz:
https://doaj.org/article/2dba904857b84f9d8242e4172fdade09
Autor:
Jiman Kang, Jedson R. Liggett, Digvijay Patil, Suman Ranjit, Katrina Loh, Anju Duttargi, Yuki Cui, Kesha Oza, Brett S. Frank, DongHyang Kwon, Bhaskar Kallakury, Simon C. Robson, Thomas M. Fishbein, Wanxing Cui, Khalid Khan, Alexander Kroemer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Innate lymphoid cells (ILCs), the most recently described family of lymphoid cells, play fundamental roles in tissue homeostasis through the production of key cytokine. Group 1 ILCs, comprised of conventional natural killer cells (cNKs) and type 1 IL
Externí odkaz:
https://doaj.org/article/b91eca92093c475fb1db88d01be3bdd4
Autor:
Xiaoliang Zhao, In‐Kyu Kim, Bhaskar Kallakury, Joeffrey J. Chahine, Eiji Iwama, Mariaelena Pierobon, Emanuel Petricoin, Justine N. McCutcheon, Yu‐Wen Zhang, Shigeki Umemura, Vincent Chen, Changli Wang, Giuseppe Giaccone
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 1130-1145 (2021)
Platinum‐based chemotherapy has been the cornerstone treatment for small cell lung cancer (SCLC) for decades, but no major progress has been made in the past 20 years with regard to overcoming chemoresistance. As the cell cycle checkpoint kinase 1
Externí odkaz:
https://doaj.org/article/e995781752ad4beab13c6c3af65e4fac
Autor:
Narayan Shivapurkar, Martha D. Gay, Aiwu (Ruth) He, Wenqiang Chen, Shermineh Golnazar, Hong Cao, Tetyana Duka, Bhaskar Kallakury, Sona Vasudevan, Jill P. Smith
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3625 (2023)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-associated deaths worldwide. Treatment with immune checkpoint antibodies has shown promise in advanced HCC, but the response is only 15–20%. We discovered a potential target for th
Externí odkaz:
https://doaj.org/article/19a37e1903aa4685bf1c0db5270a6405
Autor:
Alexander Y. Kim, Joseph H. Yacoub, David H. Field, Byoung Uk Park, Bhaskar Kallakury, Kyle E. Korolowicz, Stephan Menne
Publikováno v:
Animal Models and Experimental Medicine, Vol 3, Iss 1, Pp 98-102 (2020)
Abstract The most commonly used preclinical models of hepatocellular carcinoma (HCC) are limited for use in testing of intra‐arterial therapies such as transarterial chemoembolization and radioembolization. Issues encountered with the more commonly
Externí odkaz:
https://doaj.org/article/da05137630c74e90b7d7a17d767d294f
Autor:
Jill P. Smith, Wenqiang Chen, Narayan Shivapurkar, Monica Gerber, Robin D. Tucker, Bhaskar Kallakury, Siva Sai Krishna Dasa, Ruvanthi N. Kularatne, Stephan T. Stern
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 752 (2023)
Survival from pancreatic cancer is poor because most cancers are diagnosed in the late stages and there are no therapies to prevent the progression of precancerous pancreatic intraepithelial neoplasms (PanINs). Inhibiting mutant KRASG12D, the primary
Externí odkaz:
https://doaj.org/article/1a838750f15e4ec4a8e43ea0fe2a32b3
Autor:
Irfan Khan, Marcel O. Schmidt, Bhaskar Kallakury, Sidharth Jain, Shaunt Mehdikhani, Moshe Levi, Margarida Mendonca, William Welch, Anna T. Riegel, Christopher S. Wilcox, Anton Wellstein
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Angiotensin II can cause oxidative stress and increased blood pressure that result in long term cardiovascular pathologies. Here we evaluated the contribution of cellular senescence to the effect of chronic exposure to low dose angiotensin II in a mo
Externí odkaz:
https://doaj.org/article/d41988e59090480dbfe41577baebf916
Autor:
Monika Aggarwal, Rahul Saxena, Nasir Asif, Elizabeth Sinclair, Judy Tan, Idalia Cruz, Deborah Berry, Bhaskar Kallakury, Quynhchi Pham, Thomas T. Y. Wang, Fung-Lung Chung
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-17 (2019)
Abstract Background We reported previously that phenethyl isothiocyanate (PEITC), a dietary compound, can reactivate p53R175H mutant in vitro and in SK-BR-3 (p53R175H) breast xenograft model resulting in tumor inhibition. Because of the diversity of
Externí odkaz:
https://doaj.org/article/c91771e176b14c2fb4eb4af8e5ab9093
Autor:
Bruna M. Sugita, Yara Rodriguez, Aline S. Fonseca, Emanuelle Nunes Souza, Bhaskar Kallakury, Iglenir J. Cavalli, Enilze M. S. F. Ribeiro, Ritu Aneja, Luciane R. Cavalli
Publikováno v:
Cancers, Vol 14, Iss 9, p 2156 (2022)
MiR-150-5p is frequently deregulated in cancer, with expression and mode of action varying according to the tumor type. Here, we investigated the expression levels and role of miR-150-5p in the aggressive breast cancer subtype triple-negative breast
Externí odkaz:
https://doaj.org/article/5d153fe0c06248ae956ec701d7728b7b