Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bhaskar Halami"'
Autor:
Shahien Shahsavari, Dhananjani N. A. M. Eriyagama, Bhaskar Halami, Vagarshak Begoyan, Marina Tanasova, Jinsen Chen, Shiyue Fang
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1116-1128 (2019)
Solid-phase synthesis of electrophilic oligodeoxynucleotides (ODNs) was achieved using dimethyl-Dmoc (dM-Dmoc) as amino protecting group. Due to the high steric hindrance of the 2-(propan-2-ylidene)-1,3-dithiane side product from deprotection, the us
Externí odkaz:
https://doaj.org/article/0d61f2ae608848a0ae9c57fb9906b479
Autor:
Komal Chillar, Adikari M. D. N. Eriyagama, Yipeng Yin, Shahien Shahsavari, Bhaskar Halami, Alexander Apostle, Shiyue Fang
Publikováno v:
New Journal of Chemistry. 47:8714-8722
The use of novel protecting groups makes it possible to incorporate sensitive epigenetically modified nucleosides such as N4-acetylcytidine into oligonucleotides.
Autor:
Komal Chillar, Adikari Eriyagama, Yipeng Yin, Shahien Shahsavari, Bhaskar Halami, Alexander Apostle, Shiyue Fang
Over a hundred non-canonical nucleotides have been found in DNA and RNA. Many of these modified nucleotides are sensitive toward nucleophiles and bases. Because known solid phase DNA and RNA synthesis technologies require strongly nucleophilic and ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b474924f51aa6ca5f53609654306cc6
https://doi.org/10.26434/chemrxiv-2022-z1s7c
https://doi.org/10.26434/chemrxiv-2022-z1s7c
Autor:
Emma K Pippenger, Kai Chang, Sanaz Nourmohammadi Abadchi, Albert Leng, Bhaskar Halami, Xiaoyong Lu, Christopher R Johnson, John M Abraham, Jinny Ha, John W Harmon
Publikováno v:
Journal of the American College of Surgeons. 235:S250-S250
Autor:
Shiyue Fang, Shahien Shahsavari, Yipeng Yin, Dhananjani N. A. M. Eriyagama, Jinsen Chen, Komal Chillar, Bhaskar Halami
Publikováno v:
J Org Chem
In traditional oligodeoxynucleotide (ODN) synthesis, phosphate groups are protected with the 2-cyanoethyl group, and amino groups are protected with acyl groups. At the end of ODN synthesis, deprotection is achieved with strong bases and nucleophiles
Autor:
Vagarshak V. Begoyan, Marina Tanasova, Shiyue Fang, Bhaskar Halami, Dhananjani N. A. M. Eriyagama, Jinsen Chen, Shahien Shahsavari
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1116-1128 (2019)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Solid-phase synthesis of electrophilic oligodeoxynucleotides (ODNs) was achieved using dimethyl-Dmoc (dM-Dmoc) as amino protecting group. Due to the high steric hindrance of the 2-(propan-2-ylidene)-1,3-dithiane side product from deprotection, the us
Autor:
Xi Lin, Bhaskar Halami, Dhananjani N. A. M. Eriyagama, Shahien Shahsavari, Jinsen Chen, Yinan Yuan, Shiyue Fang
Publikováno v:
Curr Protoc Nucleic Acid Chem
This protocol provides details for the preparation of nucleoside phosphoramidites with 1,3-dithian-2-yl-methyl (Dim) and 1,3-dithian-2-yl-methoxycarbonyl (Dmoc) as protecting groups, and a linker with Dmoc as the cleavable function, then using them f
Autor:
Komal Chillar, Bao-Yuan Lu, Bhaskar Halami, Zack Nelson, Shiyue Fang, Liam Haggerty, Yipeng Yin, Brett Otto, Dhananjani N. A. M. Eriyagama, Lucas Prehoda
Publikováno v:
Tetrahedron Lett
Synthesis of three linear oligosulfoxides containing up to six sulfoxide groups was achieved by multiple SN2 reactions between an alkanethiol and alkyl tosylate to give a linear oligosulfide followed by oxidation of the oligosulfide with sodium perio
Autor:
Shahien Shahsavari, Fengping Wei, Shiyue Fang, Bhaskar Halami, Dhananjani N. A. M. Eriyagama, Bao-Yuan Lu
The catching by polymerization synthetic oligodeoxynucleotide (ODN) purification technique was shown to be potentially suitable for high-throughput purification by the purification of 12 ODNs simultaneously, to be convenient for large-scale purificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652476035689cdf2aa5995cd308ada84
https://europepmc.org/articles/PMC6428204/
https://europepmc.org/articles/PMC6428204/