Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Bhaskar C Das"'
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 11, Pp 1880-1892 (2019)
All retinoids, which can be natural and synthetic, are chemically related to vitamin A. Both natural and synthetic retinoids use specific nuclear receptors such as retinoic acid receptors and retinoid X receptors to activate specific signaling pathwa
Externí odkaz:
https://doaj.org/article/3e604c9061b94cee8ed01448c465d5f1
Autor:
Karen Mendelson, Suveg Pandey, Yu Hisano, Frank Carellini, Bhaskar C Das, Timothy Hla, Todd Evans
Publikováno v:
eLife, Vol 6 (2017)
Sphingosine-1-phosphate (S1P) is generated through phosphorylation of sphingosine by sphingosine kinases (Sphk1 and Sphk2). We show that sphk2 maternal-zygotic mutant zebrafish embryos (sphk2MZ) display early developmental phenotypes, including a del
Externí odkaz:
https://doaj.org/article/ad842b585d4f43c18c5d212ab4468be7
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10004 (2010)
Retinoids regulate key developmental pathways throughout life, and have potential uses for differentiation therapy. It should be possible to identify novel retinoids by coupling new chemical reactions with screens using the zebrafish embryonic model.
Externí odkaz:
https://doaj.org/article/55adfa2f4a4f47b4a4cef17c2a5cec91
Autor:
Amine Zorgani, Bhaskar C. Das
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
Externí odkaz:
https://doaj.org/article/4da9e4bad8be47e68d9c8f8ec7b27ddc
Autor:
Mariko Saito, Shivakumar Subbanna, Xiuli Zhang, Stefanie Canals-Baker, John F. Smiley, Donald A. Wilson, Bhaskar C. Das
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Ethanol exposure in neonatal mice induces acute neurodegeneration followed by long-lasting glial activation and GABAergic cell deficits along with behavioral abnormalities, providing a third trimester model of fetal alcohol spectrum disorders (FASD).
Externí odkaz:
https://doaj.org/article/66f6ef13dcbc424e839d900254987a98
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2757 (2023)
Drug delivery systems, which use components at the nanoscale level as diagnostic tools or to release therapeutic drugs to particular target areas in a regulated manner, are a fast-evolving field of science. The active pharmaceutical substance can be
Externí odkaz:
https://doaj.org/article/48b01e7b48f644fbb9845f520ad6b371
Publikováno v:
Molecules, Vol 28, Iss 3, p 1052 (2023)
Dearomative borylation of coumarins and chromenes via conjugate addition represents a relatively unexplored and challenging task. To address this issue, herein, we report a new and general copper (I) catalyzed dearomative borylation process to synthe
Externí odkaz:
https://doaj.org/article/5eb5181aea1f46509c11a895dbc88202
Publikováno v:
Inorganics, Vol 11, Iss 1, p 34 (2023)
Benzo[c][1,2,5]oxadiazoles and benzo[c][1,2,5]thiadiazoles are recognized to possess potent pharmacological activities including anticancer potential. In continuation of our research endeavors in the development of boron-based heterocycles as potenti
Externí odkaz:
https://doaj.org/article/5c4f14986eb1453cbacf9d1f90e42549
Publikováno v:
Adipocyte, Vol 8, Iss 1, Pp 240-253 (2019)
Adipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis and have potential anti-obesity effect. However, impairment i
Externí odkaz:
https://doaj.org/article/4e423ed13fc748fc999d4a83c087a79e
Autor:
Varsha Nandwana, Nitesh K. Nandwana, Yogarupa Das, Mariko Saito, Tanisha Panda, Sasmita Das, Frankis Almaguel, Narayan S. Hosmane, Bhaskar C. Das
Publikováno v:
Molecules, Vol 27, Iss 11, p 3402 (2022)
Hundreds of billions of commensal microorganisms live in and on our bodies, most of which colonize the gut shortly after birth and stay there for the rest of our lives. In animal models, bidirectional communications between the central nervous system
Externí odkaz:
https://doaj.org/article/fd34e150c7cd49f3a5f841ba2ed6155c