Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Bhashyam S. Iyengar"'
Publikováno v:
Journal of Heterocyclic Chemistry. 52:136-141
Three types of compounds were synthesized from carbendazim (1), a benzimidazole derivative (Scheme 1). They included a group of esters at N1 prepared by treating carbendazim with isocyanates bearing ester groups (2a, 2b, 2c), carboxyalkyl-1,2,3,4-tet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e248705ee7dc0f27c63f94b1f2d4c4
https://doi.org/10.1002/jhet.1976
https://doi.org/10.1002/jhet.1976
Autor:
Surendra Gupta, William A. Remers, Aniko M Solyom, Bhumasamudram Jagadish, Robert T. Dorr, Bhashyam S. Iyengar, Eugene A. Mash, Jason Shin Yu
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 48:165-170
A four-step synthesis of [14C]-imexon is described, starting from [14C]-phosgene. The overall yield is 27% and the specific activity is 55 mCi/mmol. Copyright © 2005 John Wiley & Sons, Ltd.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f367a24f00b08f8bf466331f8fd274a0
https://doi.org/10.1002/jlcr.911
https://doi.org/10.1002/jlcr.911
Publikováno v:
Journal of Medicinal Chemistry. 47:218-223
Chemical aspects of mode of action of imexon and related cyanoaziridines were studied. These compounds do not alkylate DNA nor react with the epsilon-amino groups of l-lysine, despite the presence of an aziridine ring. They do react readily with biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa17356e8aa6442ceb5a82b49319f1b7
https://doi.org/10.1021/jm030225v
https://doi.org/10.1021/jm030225v
Autor:
William A. Remers, David S. Alberts, Robert T. Dorr, Bhashyam S. Iyengar, Aniko M Solyom, Mary Krutzsch
Publikováno v:
Journal of Medicinal Chemistry. 40:3734-3738
Three different types of 1,4-disubstituted anthracenes were synthesized, and their cytotoxicity in a panel of tumor cells was compared with that of the corresponding 9,10-disubstituted anthracenes. The panel contained human myeloma, melanoma, colon,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f603c424819221439e6edb5353616670
https://doi.org/10.1021/jm970308+
https://doi.org/10.1021/jm970308+
Publikováno v:
ChemInform. 22
Development of an efficient synthesis of the C-D ring portion of streptonigrin is a key operation in the synthesis of this antibiotic and its analogues. A new method for the synthesis of 3-cyano-5,6-dimethyl-4-(3,4,5-trimethoxyphenyl)-2-pyridone (14)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4bb71434b4dbc21f16fbbdeac7527e5
https://doi.org/10.1002/chin.199102365
https://doi.org/10.1002/chin.199102365
Publikováno v:
ChemInform. 22
Cytidine 5'-monophosphate and 5'-ara-CMP conjugates of 2,7-diaminomitosene, with the phosphate groups linked to C-1, were prepared by treating mitomycin C with the appropriate nucleotides. 5'-UMP conjugates were prepared from mitomycin A, 7 (M-83), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::626235b2dda151e7261e35002e3c5187
https://doi.org/10.1002/chin.199152309
https://doi.org/10.1002/chin.199152309
Autor:
Bhashyam S. Iyengar, Robert T. Dorr, David S. Alberts, William A. Remers, Sydney E. Salmon, Evan M. Hersh
Publikováno v:
ChemInform. 30
A set of 20 2-cyanoaziridine-1-carboxamides was synthesized from 2-cyanoaziridine and appropriate isocyanates. These compounds were active against a variety of solid and hematological tumor cells in culture, including strains resistant to doxorubicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10274a0b2b2b33f69239b164830586f7
https://doi.org/10.1002/chin.199923126
https://doi.org/10.1002/chin.199923126
Publikováno v:
Journal of Medicinal Chemistry. 34:1947-1951
Cytidine 5'-monophosphate and 5'-ara-CMP conjugates of 2,7-diaminomitosene, with the phosphate groups linked to C-1, were prepared by treating mitomycin C with the appropriate nucleotides. 5'-UMP conjugates were prepared from mitomycin A, 7 (M-83), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52985927bc064d593fc3de77f65b51bc
https://doi.org/10.1021/jm00111a004
https://doi.org/10.1021/jm00111a004
Publikováno v:
Journal of Heterocyclic Chemistry. 27:1437-1440
Development of an efficient synthesis of the C-D ring portion of streptonigrin is a key operation in the synthesis of this antibiotic and its analogues. A new method for the synthesis of 3-cyano-5,6-dimethyl-4-(3,4,5-trimethoxyphenyl)-2-pyridone (14)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd15ebe476329507bd304ae89d17aaf
https://doi.org/10.1002/jhet.5570270547
https://doi.org/10.1002/jhet.5570270547
Autor:
Evan M. Hersh, William A. Remers, Bhashyam S. Iyengar, Robert T. Dorr, David S. Alberts, Sydney E. Salmon
Publikováno v:
Journal of medicinal chemistry. 42(3)
A set of 20 2-cyanoaziridine-1-carboxamides was synthesized from 2-cyanoaziridine and appropriate isocyanates. These compounds were active against a variety of solid and hematological tumor cells in culture, including strains resistant to doxorubicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf19cf2234c7945b6ccd3762d738223
https://pubmed.ncbi.nlm.nih.gov/9986721
https://pubmed.ncbi.nlm.nih.gov/9986721